chemokine (C-C motif) ligand 3

詳細情報を見る

同義遺伝子名

PAT 464.1, G0S19-1, chemokine (C-C motif) ligand 3, Tonsillar lymphocyte LD78 alpha protein, SCYA3, G0S19-1 protein, SIS-beta, G0/G1 switch regulatory protein 19-1, LD78ALPHA, MIP-1-alpha, MIP1A, CCL3, Small inducible cytokine A3 precursor, Macrophage inflammatory protein 1-alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:2.40 小脳:- 脳幹:- 脳梁:- 松果体:148.30 末梢神経:- 脊柱:- 網膜:- 目:41.10 動脈:- 静脈:- リンパ節:182 末梢血:419 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:9.60
GeneChip 大脳:4.76 小脳:4.55 脳幹:4.96 脳梁:6.51 松果体:- 末梢神経:5.49 脊柱:8.47 網膜:- 目:- 動脈:5.87 静脈:5.41 リンパ節:6.45 末梢血:- 脾臓:9.13 胸腺:4.77 骨髄:6.36 脂肪:6.29 骨:- 皮膚:4.87
CAGE 大脳:0.67 小脳:- 脳幹:1.22 脳梁:2.85 松果体:0 末梢神経:- 脊柱:0.42 網膜:- 目:- 動脈:2.53 静脈:1.92 リンパ節:1.78 末梢血:- 脾臓:3.14 胸腺:1.26 骨髄:- 脂肪:2.05 骨:- 皮膚:-
RNA-seq 大脳:2.87 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.26 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.35 骨:- 皮膚:-
EST 子宮:- 胎盤:40.10 前立腺:33.80 卵巣:37.30 精巣:- 心臓:25.50 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:34.20    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:17.80 乳腺:- 唾液腺:-
GeneChip 子宮:5.02 胎盤:6.84 前立腺:5.38 卵巣:5.21 精巣:4.49 心臓:4.66 骨格筋:4.46 食道:4.50 胃:5.04 腸:4.88 結腸:4.97 肝臓:6.71 肺:6.85 膀胱:- 腎臓:4.72 下垂体:4.63 甲状腺:4.80 副腎:5.16 膵臓:4.35 乳腺:5.17 唾液腺:4.79
CAGE 子宮:1.04 胎盤:2.13 前立腺:0.74 卵巣:1.37 精巣:1.44 心臓:1.25 骨格筋:0.61 食道:0.86 胃:- 腸:0.93 結腸:0.90     肝臓:2.25    肺:3.00 膀胱:1.52 腎臓:0.33 下垂体:0.26 甲状腺:0.41 副腎:- 膵臓:0.58 乳腺:1.53 唾液腺:0.62
RNA-seq 子宮:- 胎盤:- 前立腺:1.09 卵巣:1.85 精巣:1.28 心臓:0.17 骨格筋:0.26 食道:- 胃:- 腸:- 結腸:0.09     肝臓:1.09        肺:5.17    膀胱:- 腎臓:0.47 下垂体:- 甲状腺:0.34 副腎:3.49 膵臓:- 乳腺:2.70 唾液腺:-

IDs

Refseq ID NM_002983
Gene ID 6348
Unigene ID Hs.514107
Probe set ID 205114_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000006075
GTEx ID ENSG00000006075

オーソログ対応遺伝子

マウス[1]  NM_011337
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1004873
1296815
1694014
1972563
2271120
2521882
3058856
3086300
3279154
7537510
7545673
7594543
7695626
8077676
8460127
8525373
8541527
8568261
8573157
8613703
8687429
8699119
8898753
8906795
9092555
9175116
9207199
9359702
9366434
9405404
9407497
9420238
9520456
9576751
9653130
9658081
9885903
9973507
10072545
10089882
10198043
10201982
10202040
10347159
10446313
10470075
10477718
10490959
10602409
10644351
10660125
10679098
10706735
10734056
10751368
10820198
10841574
10843431
10857861
10925302
10964543
10985253
11023526
11086082
11278300
11461120
11602715
11700073
11751963
11861262
12032188
12070155
12089333
12186702
12200385
12218153
12370346
12370381
12377943
12393595
12393716
12401480
12408680
12413001
12445801
12447751
12477932
12506012
12543931
12560229
12574335
12603824
12651610
12651617
12771199
12960275
14680814
14733721
15001559
15067078
15077296
15142381
15481145
15489334
15531890
15585099
15588341
15602730
15638726
15728180
15764707
15780175
15817944
16160188
16234357
16354571
16379602
16393999
16427155
16439481
16507178
16697675
16712957
16849642
17005260
17270460
17330138
17357337
17572013
17625600
17656823
17765942
17914560
18070228
18076643
18164590
18196935
18242850
18346864
18559339
18619972
18678243
18689282
18762952
18802359
18818748
18945465
18991615
19019335
19055602
19074730
19234184
19436054
19463769
19494336
19523456
19527514
19587705
19841187
19917679
20015995
20041127
20042585
20056178
20124101
20368576
20380698
20403075
20420712
20482449
20518837
20650649
20702408
20725607
20817073
20959807
21030011
21082024
21115978
21118814
21368236
21403648
21756796
21784977
21890375
22042700
22085486
22118025
22146622
22156348
22187158
22295852
22307528
22407921
22691208
22727097
22987449
23029252
23151487
23152559
23223135
23233369
23295355
23334651
23383108
23554973
23692808
23711864
23748193
23760235
23818986
23898208
24047437
24116893
24370436
24413563

遺伝子オントロジー  (GO ID)

Biological Process

GO:0043615  astrocyte cell migration
GO:0007610  behavior
GO:0006816  calcium ion transport
GO:0019722  calcium-mediated signaling
GO:0001775  cell activation
GO:0007267  cell-cell signaling
GO:0006874  cellular calcium ion homeostasis
GO:0071346  cellular response to interferon-gamma
GO:0071347  cellular response to interleukin-1
GO:0071407  cellular response to organic cyclic substance
GO:0071356  cellular response to tumor necrosis factor
GO:0006935  chemotaxis
GO:0007010  cytoskeleton organization
GO:0048245  eosinophil chemotaxis
GO:0043308  eosinophil degranulation
GO:0006887  exocytosis
GO:0006954  inflammatory response
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0048247  lymphocyte chemotaxis
GO:0048246  macrophage chemotaxis
GO:0000165  MAPKKK cascade
GO:0002548  monocyte chemotaxis
GO:0043922  negative regulation by host of viral transcription
GO:0030502  negative regulation of bone mineralization
GO:0010629  negative regulation of gene expression
GO:0045671  negative regulation of osteoclast differentiation
GO:0030593  neutrophil chemotaxis
GO:0001649  osteoblast differentiation
GO:0016310  phosphorylation
GO:0050918  positive chemotaxis
GO:0051928  positive regulation of calcium ion transport
GO:0050850  positive regulation of calcium-mediated signaling
GO:0030335  positive regulation of cell migration
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0010628  positive regulation of gene expression
GO:0050729  positive regulation of inflammatory response
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0043525  positive regulation of neuron apoptosis
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0032760  positive regulation of tumor necrosis factor production
GO:0006468  protein amino acid phosphorylation
GO:0043491  protein kinase B signaling cascade
GO:0008360  regulation of cell shape
GO:0051930  regulation of sensory perception of pain
GO:0014808  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0070723  response to cholesterol
GO:0009636  response to toxin
GO:0010818  T cell chemotaxis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005622  intracellular

Molecular Function

GO:0004698  calcium-dependent protein kinase C activity
GO:0031726  CCR1 chemokine receptor binding
GO:0031730  CCR5 chemokine receptor binding
GO:0042056  chemoattractant activity
GO:0008009  chemokine activity
GO:0016301  kinase activity
GO:0016004  phospholipase activator activity
GO:0005515  protein binding
GO:0004672  protein kinase activity