chemokine (C-C motif) ligand 5

同義遺伝子名

T cell-specific protein P228, TCP228, Small inducible cytokine A5 precursor, D17S136E, chemokine (C-C motif) ligand 5, SISd, SIS-delta, small inducible cytokine A5 (RANTES), MGC17164, T-cell-specific RANTES protein, SCYA5, CCL5, RANTES

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:30.30

末梢血:72.90

脾臓:18.90

胸腺:-

骨髄:98.40

脂肪:40.30

骨:25.60

皮膚:57.60

GeneChip

大脳:4.50

小脳:4.68

脳幹:4.47

脳梁:4.62

松果体:-

末梢神経:5.17

脊柱:5.18

網膜:-

目:-

動脈:6.35

静脈:5.42

リンパ節:7.50

末梢血:-

脾臓:9.45

胸腺:6.08

骨髄:7.18

脂肪:6.11

骨:-

皮膚:5.68

CAGE

大脳:1.26

小脳:-

脳幹:2.35

脳梁:2.25

松果体:1.77

末梢神経:-

脊柱:2.71

網膜:-

目:-

動脈:4.31

静脈:4.97

リンパ節:4.94

末梢血:-

脾臓:5.14

胸腺:3.90

骨髄:-

脂肪:3.05

骨:-

皮膚:-

RNA-seq

大脳:0.37

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:5.83

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.45

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:45.60

胎盤:-

前立腺:45.10

卵巣:-

精巣:-

心臓:-

骨格筋:20.10

食道:-

胃:127.50

腸:64.80

結腸:8.50

肝臓:-

肺:48.90

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:6.06

胎盤:5.54

前立腺:5.69

卵巣:6.11

精巣:4.48

心臓:5.41

骨格筋:4.51

食道:5.85

胃:7.12

腸:6.60

結腸:7.16

肝臓:6.93

肺:7.71

膀胱:-

腎臓:5.04

下垂体:4.74

甲状腺:5.85

副腎:5.62

膵臓:5.02

乳腺:6.04

唾液腺:5.71

CAGE

子宮:3.47

胎盤:3.19

前立腺:3.73

卵巣:3.41

精巣:2.38

心臓:2.72

骨格筋:2.14

食道:3.34

胃:-

腸:5.16

結腸:4.10

肝臓:3.03

肺:5.19

膀胱:4.02

腎臓:2.73

下垂体:1.55

甲状腺:2.38

副腎:-

膵臓:2.66

乳腺:2.41

唾液腺:3.22

RNA-seq

子宮:-

胎盤:-

前立腺:2.99

卵巣:2.75

精巣:1.68

心臓:1.10

骨格筋:0.78

食道:-

胃:-

腸:-

結腸:2.49

肝臓:1.81

肺:6.00

膀胱:-

腎臓:0.84

下垂体:-

甲状腺:0.98

副腎:5.31

膵臓:-

乳腺:2.56

唾液腺:-

IDs

Refseq ID	NM_002985
Gene ID	6352
Unigene ID	Hs.514821
Probe set ID	204655_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000161570
GTEx ID	ENSG00000161570

オーソログ対応遺伝子

マウス[1]	NM_013653
ラット [0]

染色体

17q12 [34,198,495 - 34,207,797]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001811

Small chemokine, interleukin-8-like

遺伝子オントロジー (GO ID)

Biological Process

GO:0031584	activation of phospholipase D activity
GO:0006816	calcium ion transport
GO:0007267	cell-cell signaling
GO:0006874	cellular calcium ion homeostasis
GO:0043623	cellular protein complex assembly
GO:0071346	cellular response to interferon-gamma
GO:0071347	cellular response to interleukin-1
GO:0071407	cellular response to organic cyclic substance
GO:0071356	cellular response to tumor necrosis factor
GO:0070098	chemokine-mediated signaling pathway
GO:0006935	chemotaxis
GO:0002407	dendritic cell chemotaxis
GO:0048245	eosinophil chemotaxis
GO:0006887	exocytosis
GO:0006954	inflammatory response
GO:0007159	leukocyte adhesion
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0048246	macrophage chemotaxis
GO:0000165	MAPKKK cascade
GO:0002548	monocyte chemotaxis
GO:0043922	negative regulation by host of viral transcription
GO:0070100	negative regulation of chemokine-mediated signaling pathway
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
GO:0070233	negative regulation of T cell apoptosis
GO:0045071	negative regulation of viral genome replication
GO:0042119	neutrophil activation
GO:0050918	positive chemotaxis
GO:0010535	positive regulation of activation of JAK2 kinase activity
GO:0051928	positive regulation of calcium ion transport
GO:0045785	positive regulation of cell adhesion
GO:0030335	positive regulation of cell migration
GO:0033634	positive regulation of cell-cell adhesion mediated by integrin
GO:0031328	positive regulation of cellular biosynthetic process
GO:0034112	positive regulation of homotypic cell-cell adhesion
GO:0045089	positive regulation of innate immune response
GO:0046427	positive regulation of JAK-STAT cascade
GO:0010759	positive regulation of macrophage chemotaxis
GO:0090026	positive regulation of monocyte chemotaxis
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0042327	positive regulation of phosphorylation
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0070234	positive regulation of T cell apoptosis
GO:0010820	positive regulation of T cell chemotaxis
GO:0042102	positive regulation of T cell proliferation
GO:0045948	positive regulation of translational initiation
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
GO:0045070	positive regulation of viral genome replication
GO:0006468	protein amino acid phosphorylation
GO:0043491	protein kinase B signaling cascade
GO:0051262	protein tetramerization
GO:0002676	regulation of chronic inflammatory response
GO:0050863	regulation of T cell activation
GO:0009636	response to toxin
GO:0009615	response to virus

Cellular Component

GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space

Molecular Function

GO:0031726	CCR1 chemokine receptor binding
GO:0031729	CCR4 chemokine receptor binding
GO:0031730	CCR5 chemokine receptor binding
GO:0042056	chemoattractant activity
GO:0008009	chemokine activity
GO:0046817	chemokine receptor antagonist activity
GO:0042379	chemokine receptor binding
GO:0004435	phosphoinositide phospholipase C activity
GO:0016004	phospholipase activator activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0043621	protein self-association
GO:0030298	receptor signaling protein tyrosine kinase activator activity

chemokine (C-C motif) ligand 5

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function