secreted frizzled-related protein 1

同義遺伝子名

FRP1, FrzA, FRP-1, Secreted frizzled-related protein 1 precursor, Frizzled-related protein 1, SARP-2, secreted frizzled-related protein 1, SFRP1, sFRP-1, SARP2, Secreted apoptosis-related protein 2

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:6.25

小脳:7.64

脳幹:6.46

脳梁:7.32

松果体:-

末梢神経:7.25

脊柱:5.94

網膜:-

目:-

動脈:8.37

静脈:8.58

リンパ節:5.86

末梢血:-

脾臓:6.93

胸腺:5.19

骨髄:5.46

脂肪:8.39

骨:-

皮膚:8.32

CAGE

大脳:2.81

小脳:-

脳幹:3.16

脳梁:4.12

松果体:0.79

末梢神経:-

脊柱:2.31

網膜:-

目:-

動脈:4.73

静脈:3.77

リンパ節:2.08

末梢血:-

脾臓:2.86

胸腺:0.50

骨髄:-

脂肪:3.49

骨:-

皮膚:-

RNA-seq

大脳:3.44

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:4.49

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:3.82

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:10.31

胎盤:7.41

前立腺:8.50

卵巣:8.98

精巣:7.69

心臓:8.89

骨格筋:5.60

食道:7.24

胃:8.06

腸:7.37

結腸:7.64

肝臓:5.34

肺:5.30

膀胱:-

腎臓:8.96

下垂体:4.79

甲状腺:6.70

副腎:6.57

膵臓:5.11

乳腺:10.08

唾液腺:10.52

CAGE

子宮:5.14

胎盤:3.64

前立腺:4.00

卵巣:3.92

精巣:4.01

心臓:4.18

骨格筋:1.13

食道:3.64

胃:-

腸:2.94

結腸:3.32

肝臓:1.44

肺:1.82

膀胱:3.71

腎臓:4.71

下垂体:1.03

甲状腺:2.32

副腎:-

膵臓:1.21

乳腺:4.75

唾液腺:5.32

RNA-seq

子宮:-

胎盤:-

前立腺:5.00

卵巣:5.02

精巣:5.83

心臓:3.67

骨格筋:1.43

食道:-

胃:-

腸:-

結腸:5.01

肝臓:1.04

肺:2.37

膀胱:-

腎臓:6.16

下垂体:-

甲状腺:2.95

副腎:3.20

膵臓:-

乳腺:6.67

唾液腺:-

IDs

Refseq ID	NM_003012
Gene ID	6422
Unigene ID	-
Probe set ID	202037_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000104332
GTEx ID	ENSG00000104332

オーソログ対応遺伝子

マウス[3]	NM_013834
ラット[3]	NM_013834

染色体

8p11.21 [41,119,481 - 41,167,016]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR020067	Frizzled-like domain
IPR001134	Netrin domain
IPR018933	Netrin module, non-TIMP type
IPR008993	TIMP-like, OB-fold

遺伝子オントロジー (GO ID)

Biological Process

GO:0060346	bone trabecula formation
GO:0007420	brain development
GO:0071392	cellular response to estradiol stimulus
GO:0071391	cellular response to estrogen stimulus
GO:0071363	cellular response to growth factor stimulus
GO:0071504	cellular response to heparin
GO:0071456	cellular response to hypoxia
GO:0071347	cellular response to interleukin-1
GO:0071380	cellular response to prostaglandin E stimulus
GO:0009267	cellular response to starvation
GO:0071356	cellular response to tumor necrosis factor
GO:0071305	cellular response to vitamin D
GO:0071481	cellular response to X-ray
GO:0048546	digestive tract morphogenesis
GO:0006309	DNA fragmentation involved in apoptosis
GO:0009950	dorsal/ventral axis specification
GO:0009790	embryonic development
GO:0008585	female gonad development
GO:0008406	gonad development
GO:0002244	hemopoietic progenitor cell differentiation
GO:0060218	hemopoietic stem cell differentiation
GO:0008584	male gonad development
GO:0022601	menstrual cycle phase
GO:0060766	negative regulation of androgen receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0045578	negative regulation of B cell differentiation
GO:0030514	negative regulation of BMP signaling pathway
GO:0046851	negative regulation of bone remodeling
GO:0030308	negative regulation of cell growth
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0010719	negative regulation of epithelial to mesenchymal transition
GO:0048147	negative regulation of fibroblast proliferation
GO:0010629	negative regulation of gene expression
GO:0046676	negative regulation of insulin secretion
GO:0043508	negative regulation of JUN kinase activity
GO:0030279	negative regulation of ossification
GO:0045668	negative regulation of osteoblast differentiation
GO:0033689	negative regulation of osteoblast proliferation
GO:0045671	negative regulation of osteoclast differentiation
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0030178	negative regulation of Wnt receptor signaling pathway
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0014034	neural crest cell fate commitment
GO:0001843	neural tube closure
GO:0001649	osteoblast differentiation
GO:0090179	planar cell polarity pathway involved in neural tube closure
GO:0043065	positive regulation of apoptosis
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0001954	positive regulation of cell-matrix adhesion
GO:0050679	positive regulation of epithelial cell proliferation
GO:0045600	positive regulation of fat cell differentiation
GO:0051894	positive regulation of focal adhesion formation
GO:0032855	positive regulation of Rac GTPase activity
GO:0045880	positive regulation of smoothened signaling pathway
GO:0051496	positive regulation of stress fiber formation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0045765	regulation of angiogenesis
GO:0060687	regulation of branching involved in prostate gland morphogenesis
GO:0010564	regulation of cell cycle process
GO:0042493	response to drug
GO:0014070	response to organic cyclic substance
GO:0035019	somatic stem cell maintenance
GO:0001657	ureteric bud development
GO:0001944	vasculature development
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0042995	cell projection
GO:0009986	cell surface
GO:0005829	cytosol
GO:0031012	extracellular matrix
GO:0005615	extracellular space
GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0004197	cysteine-type endopeptidase activity
GO:0008144	drug binding
GO:0005109	frizzled binding
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0030165	PDZ domain binding
GO:0042813	Wnt receptor activity
GO:0017147	Wnt-protein binding

secreted frizzled-related protein 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function