SRY (sex determining region Y)-box 17

 詳細情報を見る

同義遺伝子名

SRY (sex determining region Y)-box 17, FLJ22252, SOX17, Transcription factor SOX-17

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:5.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:5.90 動脈:60 静脈:- リンパ節:- 末梢血:- 脾臓:37.80 胸腺:12.90 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.50 小脳:3.43 脳幹:3.63 脳梁:3.42 松果体:- 末梢神経:4.52 脊柱:3.71 網膜:- 目:- 動脈:5.06 静脈:6.12 リンパ節:3.72 末梢血:- 脾臓:5.27 胸腺:3.22 骨髄:3.69 脂肪:5.68 骨:- 皮膚:4.60
CAGE 大脳:1.35 小脳:- 脳幹:1.85 脳梁:1.73 松果体:1.70 末梢神経:- 脊柱:1.37 網膜:- 目:- 動脈:2.74 静脈:3.21 リンパ節:1.64 末梢血:- 脾臓:3.53 胸腺:1.26 骨髄:- 脂肪:4.11 骨:- 皮膚:-
RNA-seq 大脳:0.41 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.17 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.61 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:27.30 胎盤:- 前立腺:22.50 卵巣:37.30 精巣:8.70 心臓:- 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:-     肝臓:-        肺:14.70    膀胱:- 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:- 唾液腺:-
GeneChip 子宮:5.95 胎盤:4.19 前立腺:3.76 卵巣:5.27 精巣:3.90 心臓:5.77 骨格筋:4.09 食道:4.24 胃:4.32 腸:4.30 結腸:4.82 肝臓:3.63 肺:4.49 膀胱:- 腎臓:3.91 下垂体:3.67 甲状腺:3.86 副腎:4.12 膵臓:3.52 乳腺:4.70 唾液腺:3.34
CAGE 子宮:3.82 胎盤:3.05 前立腺:2.97 卵巣:3.40 精巣:2.27 心臓:3.19 骨格筋:3.05 食道:3.29 胃:- 腸:1.63 結腸:2.38     肝臓:1.37    肺:3.20 膀胱:3.35 腎臓:2.05 下垂体:0.72 甲状腺:2.06 副腎:- 膵臓:1.42 乳腺:4.30 唾液腺:1.00
RNA-seq 子宮:- 胎盤:- 前立腺:3.31 卵巣:1.98 精巣:2.46 心臓:1.99 骨格筋:2.15 食道:- 胃:- 腸:- 結腸:2.33     肝臓:0.97        肺:3.21    膀胱:- 腎臓:1.70 下垂体:- 甲状腺:0.86 副腎:2.96 膵臓:- 乳腺:2.97 唾液腺:-

詳細情報

IDs

Refseq ID NM_022454
Gene ID 64321
Unigene ID Hs.98367
Probe set ID 219993_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164736
GTEx ID ENSG00000164736

オーソログ対応遺伝子

マウス[2]  NM_011441
ラット[1]  NM_001107902

染色体

8q11.23  [55,370,495  -  55,373,448]

遺伝子ファミリー (Interpro ID)

IPR000910  High mobility group, HMG1/HMG2
IPR009071  High mobility group, superfamily

Link to Pubmed  (Pubmed ID)

11786926
12100890
12194848
12477932
14702039
15163629
16344560
17875931
18413743
18523156
18564921
18682240
18940723
18997786
19301122
19369635
19549530
19736317
20364137
20716954
20960469
21305474
21362573
21457403
21514720
21760905
21957254
22161215
22348788
22846201
22921431
22961961
23044318
23061670
23136251
23169777
23241958
23403728
23474492
23813959
23918253
23999170
24097068

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060913  cardiac cell fate determination
GO:0003142  cardiogenic plate morphogenesis
GO:0042074  cell migration involved in gastrulation
GO:0048617  embryonic foregut morphogenesis
GO:0035050  embryonic heart tube development
GO:0003143  embryonic heart tube morphogenesis
GO:0060956  endocardial cell differentiation
GO:0060214  endocardium formation
GO:0001706  endoderm formation
GO:0007493  endodermal cell fate determination
GO:0060914  heart formation
GO:0001947  heart looping
GO:0001828  inner cell mass cellular morphogenesis
GO:0042789  mRNA transcription from RNA polymerase II promoter
GO:0030308  negative regulation of cell growth
GO:0042662  negative regulation of mesodermal cell fate specification
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0003308  negative regulation of Wnt receptor signaling pathway involved in heart development
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0003151  outflow tract morphogenesis
GO:0045597  positive regulation of cell differentiation
GO:0045732  positive regulation of protein catabolic process
GO:0048643  positive regulation of skeletal muscle tissue development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0031648  protein destabilization
GO:0050821  protein stabilization
GO:0045995  regulation of embryonic development
GO:0060807  regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification
GO:0006355  regulation of transcription, DNA-dependent
GO:0021903  rostrocaudal neural tube patterning
GO:0007283  spermatogenesis
GO:0048866  stem cell fate specification
GO:0001570  vasculogenesis
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008013  beta-catenin binding
GO:0044212  DNA regulatory region binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding