sonic hedgehog homolog (Drosophila)

詳細情報を見る

同義遺伝子名

sonic hedgehog homolog (Drosophila), SHH, HPE3, HLP3, HHG1, Sonic hedgehog protein precursor, SMMCI, HHG-1, sonic hedgehog (Drosophila) homolog

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:13 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:5.90 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.70 小脳:3.86 脳幹:3.63 脳梁:3.59 松果体:- 末梢神経:3.92 脊柱:3.67 網膜:- 目:- 動脈:3.97 静脈:4.03 リンパ節:3.99 末梢血:- 脾臓:3.62 胸腺:3.79 骨髄:3.95 脂肪:3.96 骨:- 皮膚:4.11
CAGE 大脳:0.91 小脳:- 脳幹:1.15 脳梁:0.63 松果体:0 末梢神経:- 脊柱:0.82 網膜:- 目:- 動脈:0.18 静脈:0 リンパ節:0.06 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.09 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:21.10        肺:4.90    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:3.74 胎盤:3.47 前立腺:3.73 卵巣:4.04 精巣:3.80 心臓:3.79 骨格筋:3.93 食道:3.89 胃:3.75 腸:3.93 結腸:3.73 肝臓:3.75 肺:3.84 膀胱:- 腎臓:3.74 下垂体:3.95 甲状腺:3.93 副腎:3.98 膵臓:4.06 乳腺:3.92 唾液腺:3.88
CAGE 子宮:1.31 胎盤:0.16 前立腺:2.17 卵巣:0.14 精巣:0.36 心臓:0.10 骨格筋:0.05 食道:0.33 胃:- 腸:1.15 結腸:0.97     肝臓:2.92    肺:1.28 膀胱:2.48 腎臓:1.70 下垂体:0.34 甲状腺:0 副腎:- 膵臓:0.58 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:1.15 卵巣:0.01 精巣:0.21 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0.72        肺:0.23    膀胱:- 腎臓:0.64 下垂体:- 甲状腺:0 副腎:0.05 膵臓:- 乳腺:0.02 唾液腺:-

IDs

Refseq ID NM_000193
Gene ID 6469
Unigene ID Hs.164537
Probe set ID 207586_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164690
GTEx ID ENSG00000164690

オーソログ対応遺伝子

マウス[1]  NM_009170
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7590746
7720571
8012391
8012392
8269518
8647801
8896571
8896572
8906787
9115210
9302262
9593755
9811851
10050855
10441331
10556296
10654605
11001584
11076863
11175816
11331587
11359461
11395778
11471164
11572986
11576188
11857543
11983699
12032320
12221011
12394760
12417650
12421920
12477932
12495844
12503095
12514186
12533514
12547712
12629553
12632368
12690205
12709790
12773389
12783258
12837695
12853948
12917489
12926841
14520411
14520413
14691301
14727139
14733907
14764698
15128061
15170664
15221788
15238528
15249145
15249678
15292211
15314219
15470048
15502857
15521068
15592520
15675968
15790807
15905200
15939571
15998911
16003737
16159933
16244652
16282375
16300466
16322088
16323008
16335952
16448649
16528374
16540513
16571640
16701100
16778137
16786128
16945339
17007023
17035233
17050669
17102592
17152067
17227833
17353904
17378681
17390043
17392427
17409199
17414057
17461467
17507406
17611415
17628016
17761145
17850284
17895245
17914115
17927850
18063705
18156157
18174246
18178630
18308861
18332216
18410549
18417549
18422746
18425375
18463159
18524848
18534984
18629868
18655123
18661269
18691547
18701018
18772349
18776754
18776995
18787206
18788453
18829478
18836447
18953259
18974107
18997815
19004543
19055941
19057928
19074837
19177589
19219074
19240184
19244133
19254376
19291772
19363151
19398181
19407245
19431187
19432668
19453261
19460624
19540662
19548265
19561609
19564910
19577569
19593328
19603532
19622100
19629560
19633682
19662327
19730683
19738389
19784071
19788370
19801637
19834598
19836325
19847792
19856079
19862523
19901516
19906872
19920144
19952108
19996099
20015350
20026066
20053908
20066439
20087349
20137639
20146882
20186790
20200556
20218977
20219995
20301552
20301702
20336604
20425842
20440271
20508033
20512148
20526338
20531442
20538960
20561215
20564213
20578145
20619754
20634891
20643644
20720195
20842831
20854074
20938369
20972907
21039988
21059263
21110116
21129534
21172305
21190179
21249152
21338440
21357747
21372638
21376786
21424326
21434830
21441223
21496866
21498615
21520153
21537345
21597001
21633164
21646478
21649559
21685941
21707705
21720384
21732818
21824197
21861243
21940735
21940988
21945071
21953141
21975935
21984201
22020162
22049079
22052462
22056874
22114142
22123293
22125638
22130025
22144466
22240607
22241722
22262830
22264144
22264356
22310223
22350753
22354771
22388744
22407314
22432023
22461522
22486854
22513293
22535603
22543708
22554932
22559324
22581926
22609357
22677152
22679015
22683912
22786669
22791840
22797776
22811598
22875023
22897141
22901214
22902404
22903933
22941587
22948179
22995914
23023967
23027863
23027964
23041623
23091001
23112049
23172661
23249701
23284750
23322567
23336661
23340176
23395608
23468532
23476075
23493353
23504944
23551431
23596255
23667589
23835807
23867461
23867465
23894369
23934731
23935859
23967143
23998958
24004862
24072710
24076665
24095799
24174682
24366871

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008209  androgen metabolic process
GO:0009952  anterior/posterior pattern formation
GO:0006915  apoptosis
GO:0060840  artery development
GO:0007411  axon guidance
GO:0060020  Bergmann glial cell differentiation
GO:0007596  blood coagulation
GO:0060445  branching involved in salivary gland morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0048754  branching morphogenesis of a tube
GO:0060447  bud outgrowth involved in lung branching
GO:0043010  camera-type eye development
GO:0043369  CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0048468  cell development
GO:0001708  cell fate specification
GO:0007267  cell-cell signaling
GO:0071285  cellular response to lithium ion
GO:0007417  central nervous system development
GO:0003140  determination of left/right asymmetry in lateral mesoderm
GO:0021904  dorsal/ventral neural tube patterning
GO:0009953  dorsal/ventral pattern formation
GO:0007398  ectoderm development
GO:0009790  embryonic development
GO:0042733  embryonic digit morphogenesis
GO:0048617  embryonic foregut morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0035116  embryonic hindlimb morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0009880  embryonic pattern specification
GO:0048706  embryonic skeletal system development
GO:0006897  endocytosis
GO:0060664  epithelial cell proliferation involved in salivary gland morphogenesis
GO:0060738  epithelial-mesenchymal signaling involved in prostate gland development
GO:0030010  establishment of cell polarity
GO:0030900  forebrain development
GO:0048859  formation of anatomical boundary
GO:0031069  hair follicle morphogenesis
GO:0007507  heart development
GO:0001947  heart looping
GO:0030902  hindbrain development
GO:0007442  hindgut morphogenesis
GO:0048839  inner ear development
GO:0016539  intein-mediated protein splicing
GO:0045109  intermediate filament organization
GO:0060459  left lung development
GO:0060174  limb bud formation
GO:0030324  lung development
GO:0060428  lung epithelium development
GO:0060463  lung lobe morphogenesis
GO:0060484  lung-associated mesenchyme development
GO:0002320  lymphoid progenitor cell differentiation
GO:0030539  male genitalia development
GO:0060916  mesenchymal cell proliferation involved in lung development
GO:0060783  mesenchymal smoothened signaling pathway involved in prostate gland development
GO:0001656  metanephros development
GO:0030901  midbrain development
GO:0080125  multicellular structure septum development
GO:0045445  myoblast differentiation
GO:0014902  myotube differentiation
GO:0046639  negative regulation of alpha-beta T cell differentiation
GO:0045596  negative regulation of cell differentiation
GO:0030336  negative regulation of cell migration
GO:0032435  negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034244  negative regulation of RNA elongation from RNA polymerase II promoter
GO:0042130  negative regulation of T cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0045060  negative thymic T cell selection
GO:0001755  neural crest cell migration
GO:0007405  neuroblast proliferation
GO:0048663  neuron fate commitment
GO:0042475  odontogenesis of dentine-containing tooth
GO:0014003  oligodendrocyte development
GO:0048645  organ formation
GO:0002076  osteoblast development
GO:0060021  palate development
GO:0031016  pancreas development
GO:0007389  pattern specification process
GO:0001569  patterning of blood vessels
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0060769  positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0007228  positive regulation of hh target transcription factor activity
GO:0033092  positive regulation of immature T cell proliferation in the thymus
GO:0002052  positive regulation of neuroblast proliferation
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0042307  positive regulation of protein import into nucleus
GO:0014858  positive regulation of skeletal muscle cell proliferation
GO:0048643  positive regulation of skeletal muscle tissue development
GO:0045880  positive regulation of smoothened signaling pathway
GO:0051155  positive regulation of striated muscle cell differentiation
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0045059  positive thymic T cell selection
GO:0060516  primary prostatic bud elongation
GO:0060523  prostate epithelial cord elongation
GO:0030850  prostate gland development
GO:0034504  protein localization in nucleus
GO:0006508  proteolysis
GO:0042981  regulation of apoptosis
GO:0042127  regulation of cell proliferation
GO:0060782  regulation of mesenchymal cell proliferation involved in prostate gland development
GO:0042481  regulation of odontogenesis
GO:0060685  regulation of prostatic bud formation
GO:0030162  regulation of proteolysis
GO:0060458  right lung development
GO:0060662  salivary gland cavitation
GO:0007224  smoothened signaling pathway
GO:0021938  smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation
GO:0021513  spinal cord dorsal/ventral patterning
GO:0021522  spinal cord motor neuron differentiation
GO:0048864  stem cell development
GO:0033077  T cell differentiation in the thymus
GO:0021978  telencephalon regionalization
GO:0021794  thalamus development
GO:0048538  thymus development
GO:0030878  thyroid gland development
GO:0060439  trachea morphogenesis
GO:0001570  vasculogenesis
GO:0007418  ventral midline development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986  cell surface
GO:0031012  extracellular matrix
GO:0005615  extracellular space
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0001948  glycoprotein binding
GO:0005539  glycosaminoglycan binding
GO:0043237  laminin-1 binding
GO:0016015  morphogen activity
GO:0005113  patched binding
GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0004871  signal transducer activity
GO:0008270  zinc ion binding