bone morphogenetic protein 4

同義遺伝子名

Bone morphogenetic protein 4 precursor, DVR4, BMP4, BMP2B1, BMP-2B, bone morphogenetic protein 4, BMP2B, ZYME, BMP 4, BMP-4

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:5.90

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:52.90

動脈:-

静脈:66.60

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:40.30

骨:12.80

皮膚:24

GeneChip

大脳:6.04

小脳:6.23

脳幹:6.16

脳梁:5.89

松果体:-

末梢神経:6.41

脊柱:6.19

網膜:-

目:-

動脈:7.27

静脈:6.80

リンパ節:6.48

末梢血:-

脾臓:6.40

胸腺:5.90

骨髄:6.14

脂肪:7.12

骨:-

皮膚:6.62

CAGE

大脳:0.74

小脳:-

脳幹:0.73

脳梁:1.15

松果体:0.71

末梢神経:-

脊柱:1.03

網膜:-

目:-

動脈:2.10

静脈:1.34

リンパ節:1.05

末梢血:-

脾臓:0.99

胸腺:0.33

骨髄:-

脂肪:1.63

骨:-

皮膚:-

RNA-seq

大脳:0.00

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.95

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.77

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:69.20

前立腺:11.30

卵巣:-

精巣:8.70

心臓:12.80

骨格筋:-

食道:-

胃:169.90

腸:-

結腸:67.80

肝臓:-

肺:9.80

膀胱:-

腎臓:10.40

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:18.60

唾液腺:-

GeneChip

子宮:6.92

胎盤:6.66

前立腺:7.01

卵巣:6.77

精巣:5.82

心臓:6.90

骨格筋:6.53

食道:6.63

胃:7.88

腸:7.08

結腸:7.49

肝臓:6.25

肺:6.86

膀胱:-

腎臓:6.68

下垂体:6.46

甲状腺:6.46

副腎:7.47

膵臓:5.81

乳腺:7.10

唾液腺:6.39

CAGE

子宮:1.69

胎盤:2.40

前立腺:2.87

卵巣:1.53

精巣:0.71

心臓:1.94

骨格筋:1.18

食道:1.60

胃:-

腸:1.67

結腸:2.10

肝臓:0.96

肺:1.84

膀胱:2.13

腎臓:1.55

下垂体:0.98

甲状腺:1.73

副腎:-

膵臓:0.58

乳腺:2.19

唾液腺:1.39

RNA-seq

子宮:-

胎盤:-

前立腺:0.17

卵巣:0.20

精巣:0.28

心臓:0.00

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.49

肝臓:0.00

肺:0.00

膀胱:-

腎臓:0.87

下垂体:-

甲状腺:0.42

副腎:1.00

膵臓:-

乳腺:0.33

唾液腺:-

IDs

Refseq ID	NM_130851
Gene ID	652
Unigene ID	Hs.68879
Probe set ID	211518_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000125378
GTEx ID	ENSG00000125378

オーソログ対応遺伝子

マウス[1]	NM_007554
ラット [0]

染色体

14q22.2 [54,416,454 - 54,423,529]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0009948	anterior/posterior axis specification
GO:0002043	blood vessel endothelial cell proliferation during sprouting angiogenesis
GO:0030509	BMP signaling pathway
GO:0003130	BMP signaling pathway involved in heart induction
GO:0060441	branching involved in lung morphogenesis
GO:0060442	branching involved in prostate gland morphogenesis
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0048754	branching morphogenesis of a tube
GO:0060433	bronchus development
GO:0060503	bud dilation involved in lung branching
GO:0060449	bud elongation involved in lung branching
GO:0055007	cardiac muscle cell differentiation
GO:0003279	cardiac septum development
GO:0071363	cellular response to growth factor stimulus
GO:0002062	chondrocyte differentiation
GO:0060197	cloacal septation
GO:0007182	common-partner SMAD protein phosphorylation
GO:0060363	cranial suture morphogenesis
GO:0021904	dorsal/ventral neural tube patterning
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0042733	embryonic digit morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0060272	embryonic skeletal joint morphogenesis
GO:0003197	endocardial cushion development
GO:0001958	endochondral ossification
GO:0060502	epithelial cell proliferation involved in lung morphogenesis
GO:0060684	epithelial-mesenchymal cell signaling
GO:0030218	erythrocyte differentiation
GO:0030198	extracellular matrix organization
GO:0007281	germ cell development
GO:0002244	hemopoietic progenitor cell differentiation
GO:0060113	inner ear receptor cell differentiation
GO:0048392	intermediate mesodermal cell differentiation
GO:0001822	kidney development
GO:0060235	lens induction in camera-type eye
GO:0048286	lung alveolus development
GO:0060425	lung morphogenesis
GO:0002320	lymphoid progenitor cell differentiation
GO:0030225	macrophage differentiation
GO:0060592	mammary gland formation
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0007500	mesodermal cell fate determination
GO:0001823	mesonephros development
GO:0030224	monocyte differentiation
GO:0043066	negative regulation of apoptosis
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
GO:0045786	negative regulation of cell cycle
GO:0060548	negative regulation of cell death
GO:0008285	negative regulation of cell proliferation
GO:0032331	negative regulation of chondrocyte differentiation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0090194	negative regulation of glomerulus development
GO:0033088	negative regulation of immature T cell proliferation in the thymus
GO:0043407	negative regulation of MAP kinase activity
GO:0045839	negative regulation of mitosis
GO:0045662	negative regulation of myoblast differentiation
GO:0042326	negative regulation of phosphorylation
GO:0060686	negative regulation of prostatic bud formation
GO:0045843	negative regulation of striated muscle tissue development
GO:0033085	negative regulation of T cell differentiation in the thymus
GO:0070244	negative regulation of thymocyte apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0001843	neural tube closure
GO:0048663	neuron fate commitment
GO:0042476	odontogenesis
GO:0042475	odontogenesis of dentine-containing tooth
GO:0001649	osteoblast differentiation
GO:0003323	pancreatic B cell development
GO:0021983	pituitary gland development
GO:0050918	positive chemotaxis
GO:0043065	positive regulation of apoptosis
GO:0030513	positive regulation of BMP signaling pathway
GO:0030501	positive regulation of bone mineralization
GO:0055020	positive regulation of cardiac muscle fiber development
GO:0010942	positive regulation of cell death
GO:0032967	positive regulation of collagen biosynthetic process
GO:0045603	positive regulation of endothelial cell differentiation
GO:0010595	positive regulation of endothelial cell migration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0050679	positive regulation of epithelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0090184	positive regulation of kidney development
GO:0045666	positive regulation of neuron differentiation
GO:0045778	positive regulation of ossification
GO:0045669	positive regulation of osteoblast differentiation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0060391	positive regulation of SMAD protein nuclear translocation
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009791	post-embryonic development
GO:0034504	protein localization in nucleus
GO:0060687	regulation of branching involved in prostate gland morphogenesis
GO:0042487	regulation of odontogenesis of dentine-containing tooth
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
GO:0051150	regulation of smooth muscle cell differentiation
GO:0003014	renal system process
GO:0003139	secondary heart field specification
GO:0060395	SMAD protein signal transduction
GO:0048745	smooth muscle tissue development
GO:0007224	smoothened signaling pathway
GO:0010159	specification of organ position
GO:0043401	steroid hormone mediated signaling pathway
GO:0021537	telencephalon development
GO:0021978	telencephalon regionalization
GO:0060438	trachea development
GO:0060440	trachea formation
GO:0001657	ureteric bud development

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0070700	BMP receptor binding
GO:0042056	chemoattractant activity
GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0008201	heparin binding
GO:0005515	protein binding

bone morphogenetic protein 4

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function