SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

詳細情報を見る

同義遺伝子名

hSNF2b, Brahma protein homolog 1, SNF2L4, BRG1, BAF190, BRG-1 protein, SMARCA4, SNF2-BETA, Probable global transcription activator SNF2L4, SNF2-beta, SNF2LB, SNF2B, ATP-dependent helicase SMARCA4, Mitotic growth and transcription activator

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:133.90 小脳:113.30 脳幹:- 脳梁:233.30 松果体:- 末梢神経:153.40 脊柱:- 網膜:118.60 目:229.20 動脈:149.90 静脈:1266.30 リンパ節:323.50 末梢血:72.90 脾臓:94.50 胸腺:309.20 骨髄:98.40 脂肪:- 骨:51.20 皮膚:264
GeneChip 大脳:7.64 小脳:7.61 脳幹:7.66 脳梁:7.34 松果体:- 末梢神経:7.45 脊柱:7.37 網膜:- 目:- 動脈:7.25 静脈:7.27 リンパ節:7.48 末梢血:- 脾臓:7.34 胸腺:8.50 骨髄:7.37 脂肪:7.14 骨:- 皮膚:7.88
CAGE 大脳:3.61 小脳:- 脳幹:3.34 脳梁:3.59 松果体:4.05 末梢神経:- 脊柱:3.11 網膜:- 目:- 動脈:3.11 静脈:3.40 リンパ節:3.67 末梢血:- 脾臓:3.39 胸腺:4.69 骨髄:- 脂肪:2.96 骨:- 皮膚:-
RNA-seq 大脳:0.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.42 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.16 骨:- 皮膚:-
EST 子宮:45.60 胎盤:98.40 前立腺:101.40 卵巣:111.80 精巣:116.80 心臓:255.40 骨格筋:40.20 食道:- 胃:191.20 腸:32.40 結腸:152.60     肝臓:42.20        肺:146.60    膀胱:- 腎臓:124.80 下垂体:- 甲状腺:- 副腎:- 膵臓:53.30 乳腺:334.50 唾液腺:328.40
GeneChip 子宮:7.62 胎盤:7.62 前立腺:7.92 卵巣:7.69 精巣:8.75 心臓:6.80 骨格筋:6.78 食道:8.13 胃:7.20 腸:7.21 結腸:7.34 肝臓:6.71 肺:7.38 膀胱:- 腎臓:7.62 下垂体:7.41 甲状腺:7.52 副腎:7.23 膵臓:6.75 乳腺:7.79 唾液腺:7.17
CAGE 子宮:3.27 胎盤:3.38 前立腺:3.21 卵巣:3.44 精巣:3.85 心臓:3.09 骨格筋:3.25 食道:3.67 胃:- 腸:3.29 結腸:3.38     肝臓:2.97    肺:3.25 膀胱:3.14 腎臓:3.37 下垂体:3.17 甲状腺:2.88 副腎:- 膵臓:3.26 乳腺:2.83 唾液腺:3.13
RNA-seq 子宮:- 胎盤:- 前立腺:0.50 卵巣:0.20 精巣:0.00 心臓:0.00 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.00     肝臓:0.01        肺:0.00    膀胱:- 腎臓:0.42 下垂体:- 甲状腺:0.57 副腎:0.21 膵臓:- 乳腺:0.00 唾液腺:-

IDs

Refseq ID NM_001128845
Gene ID 6597
Unigene ID Hs.327527
Probe set ID 214728_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000127616
GTEx ID ENSG00000127616

オーソログ対応遺伝子

マウス[2]  NM_001174078, NM_001174079, NM_011417
ラット[1]  NM_134368, NM_001174079, NM_011417

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7739891
7923370
8208605
8232556
8670841
8804307
8856972
8895581
9099865
9128241
9222609
9443979
9584200
9590696
9744861
9845365
9891079
10078207
10204490
10619021
10688647
10778858
10943845
10944117
11003650
11003653
11013263
11018012
11078522
11085541
11108719
11238380
11371506
11414763
11445556
11486022
11532957
11719516
11726552
11734557
11779498
11784859
11805098
11839798
11937040
11950834
11953317
11988099
12044884
12065415
12077331
12154023
12192000
12192045
12200431
12244326
12368262
12411497
12434308
12477932
12493776
12566296
12612078
12620226
12637547
12684665
12889071
12917342
14499622
14530259
14530271
14555651
14559996
14603256
14673171
14676191
14701856
14702039
14729568
14743216
14966121
14990991
15034933
15035981
15057824
15075294
15140983
15141164
15150092
15170388
15207703
15231747
15240517
15286705
15287030
15302935
15317818
15347669
15485920
15616580
15635413
15731117
15774904
15780937
15781111
15870273
15882967
15887247
15985610
15999204
16024661
16051670
16147992
16195385
16217013
16230384
16252006
16287714
16322236
16424906
16452305
16469706
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16537901
16552721
16565076
16675956
16687403
16730941
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16800816
16824695
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16940996
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17599918
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17938176
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18042045
18086889
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18386774
18414052
18451880
18487222
18500344
18508648
18660489
18809673
18816825
19061646
19066270
19081374
19144648
19149898
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19220418
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19371634
19448667
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19471022
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19596686
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19762545
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20011120
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20129940
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20353823
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20697355
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20951943
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21079652
21092585
21102582
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21139048
21145461
21252943
21284845
21300803
21317927
21347282
21360626
21378990
21520050
21532573
21549307
21555518
21670149
21683060
21693764
21699904
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21795385
21890473
21900401
21906983
21940037
21963585
22068056
22162999
22192413
22196727
22242598
22262178
22268729
22285184
22334708
22362300
22363625
22403242
22407764
22408259
22425674
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22563078
22573825
22586326
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22751105
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23000965
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23349796
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23775540
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23872584
23897427
24042015
24190014
24250222
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24362264
24421395
24457600
24550385
24583282
24658001
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24658004
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001832  blastocyst growth
GO:0001835  blastocyst hatching
GO:0000902  cell morphogenesis
GO:0006338  chromatin remodeling
GO:0060318  definitive erythrocyte differentiation
GO:0010424  DNA methylation on cytosine within a CG sequence
GO:0035116  embryonic hindlimb morphogenesis
GO:0048562  embryonic organ morphogenesis
GO:0048730  epidermis morphogenesis
GO:0030198  extracellular matrix organization
GO:0030900  forebrain development
GO:0007403  glial cell fate determination
GO:0060347  heart trabecula formation
GO:0030902  hindbrain development
GO:0043966  histone H3 acetylation
GO:0030216  keratinocyte differentiation
GO:0001889  liver development
GO:0006346  methylation-dependent chromatin silencing
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0030308  negative regulation of cell growth
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007070  negative regulation of transcription from RNA polymerase II promoter, mitotic
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0003407  neural retina development
GO:0006337  nucleosome disassembly
GO:0043923  positive regulation by host of viral transcription
GO:0043388  positive regulation of DNA binding
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0019827  stem cell maintenance
GO:0001570  vasculogenesis

Cellular Component

GO:0000792  heterochromatin
GO:0000790  nuclear chromatin
GO:0005719  nuclear euchromatin
GO:0005634  nucleus
GO:0005726  perichromatin fibrils
GO:0016514  SWI/SNF complex

Molecular Function

GO:0050681  androgen receptor binding
GO:0005524  ATP binding
GO:0003682  chromatin binding
GO:0008094  DNA-dependent ATPase activity
GO:0004386  helicase activity
GO:0070577  histone acetyl-lysine binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0047485  protein N-terminus binding
GO:0030957  Tat protein binding
GO:0003713  transcription coactivator activity
GO:0003714  transcription corepressor activity