superoxide dismutase 1, soluble

詳細情報を見る

同義遺伝子名

SOD1, ALS1, homodimer, ALS, SOD, Superoxide dismutase [Cu-Zn], IPOA

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:225.20 小脳:75.60 脳幹:- 脳梁:58.30 松果体:148.30 末梢神経:368.10 脊柱:112.30 網膜:118.60 目:399.60 動脈:539.60 静脈:199.90 リンパ節:70.80 末梢血:164 脾臓:18.90 胸腺:64.40 骨髄:255.80 脂肪:322.70 骨:166.30 皮膚:211.20
GeneChip 大脳:10.95 小脳:10.41 脳幹:11.54 脳梁:10.50 松果体:- 末梢神経:11.57 脊柱:10.92 網膜:- 目:- 動脈:10.34 静脈:10.42 リンパ節:9.88 末梢血:- 脾臓:9.68 胸腺:10.18 骨髄:9.54 脂肪:10.23 骨:- 皮膚:10.01
CAGE 大脳:6.22 小脳:- 脳幹:6.17 脳梁:5.26 松果体:6.25 末梢神経:- 脊柱:6.53 網膜:- 目:- 動脈:6.13 静脈:5.57 リンパ節:5.04 末梢血:- 脾臓:4.74 胸腺:4.65 骨髄:- 脂肪:5.27 骨:- 皮膚:-
RNA-seq 大脳:8.29 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:7.10 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:7.39 骨:- 皮膚:-
EST 子宮:118.50 胎盤:145.70 前立腺:214 卵巣:74.50 精巣:142.80 心臓:281 骨格筋:221 食道:- 胃:361.10 腸:162 結腸:169.60     肝臓:411.70        肺:254.20    膀胱:- 腎臓:20.80 下垂体:- 甲状腺:327.50 副腎:203.10 膵臓:649.10 乳腺:65.10 唾液腺:-
GeneChip 子宮:10.26 胎盤:10.47 前立腺:10.79 卵巣:10.68 精巣:10.12 心臓:10.45 骨格筋:10.22 食道:10.29 胃:9.78 腸:10.10 結腸:10.16 肝臓:11.91 肺:9.91 膀胱:- 腎臓:11.05 下垂体:10.36 甲状腺:10.35 副腎:11.21 膵臓:9.28 乳腺:10.17 唾液腺:9.25
CAGE 子宮:5.03 胎盤:5.58 前立腺:5.32 卵巣:5.15 精巣:5.21 心臓:6.56 骨格筋:6.08 食道:5.30 胃:- 腸:5.85 結腸:5.72     肝臓:7.00    肺:5.29 膀胱:5.31 腎臓:5.81 下垂体:5.48 甲状腺:5.56 副腎:- 膵臓:5.47 乳腺:6.99 唾液腺:4.75
RNA-seq 子宮:- 胎盤:- 前立腺:7.69 卵巣:7.66 精巣:7.76 心臓:7.23 骨格筋:6.70 食道:- 胃:- 腸:- 結腸:8.12     肝臓:8.86        肺:6.96    膀胱:- 腎臓:7.75 下垂体:- 甲状腺:8.32 副腎:7.34 膵臓:- 乳腺:7.64 唾液腺:-

IDs

Refseq ID NM_000454
Gene ID 6647
Unigene ID Hs.443914
Probe set ID 200642_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000142168
GTEx ID ENSG00000142168

オーソログ対応遺伝子

マウス[2]  NM_011434
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0008089  anterograde axon cargo transport
GO:0060088  auditory receptor cell stereocilium organization
GO:0007596  blood coagulation
GO:0007569  cell aging
GO:0006879  cellular iron ion homeostasis
GO:0006309  DNA fragmentation involved in apoptosis
GO:0006302  double-strand break repair
GO:0007566  embryo implantation
GO:0006749  glutathione metabolic process
GO:0060047  heart contraction
GO:0050665  hydrogen peroxide biosynthetic process
GO:0007626  locomotory behavior
GO:0046716  muscle homeostasis
GO:0032287  myelin maintenance in the peripheral nervous system
GO:0002262  myeloid cell homeostasis
GO:0045541  negative regulation of cholesterol biosynthetic process
GO:0043524  negative regulation of neuron apoptosis
GO:0060052  neurofilament cytoskeleton organization
GO:0001541  ovarian follicle development
GO:0001890  placenta development
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0043065  positive regulation of apoptosis
GO:0043085  positive regulation of catalytic activity
GO:0001819  positive regulation of cytokine production
GO:0032930  positive regulation of superoxide release
GO:0008217  regulation of blood pressure
GO:0051881  regulation of mitochondrial membrane potential
GO:0040014  regulation of multicellular organism growth
GO:0046620  regulation of organ growth
GO:0045859  regulation of protein kinase activity
GO:0032314  regulation of Rac GTPase activity
GO:0033081  regulation of T cell differentiation in the thymus
GO:0060087  relaxation of vascular smooth muscle
GO:0019430  removal of superoxide radicals
GO:0001975  response to amphetamine
GO:0048678  response to axon injury
GO:0046688  response to copper ion
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0009408  response to heat
GO:0042542  response to hydrogen peroxide
GO:0031667  response to nutrient levels
GO:0010033  response to organic substance
GO:0000303  response to superoxide
GO:0001895  retina homeostasis
GO:0008090  retrograde axon cargo transport
GO:0007605  sensory perception of sound
GO:0007283  spermatogenesis
GO:0042554  superoxide anion generation
GO:0006801  superoxide metabolic process
GO:0048538  thymus development
GO:0019226  transmission of nerve impulse

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0032839  dendrite cytoplasm
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005777  peroxisome
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0051087  chaperone binding
GO:0005507  copper ion binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0030346  protein phosphatase 2B binding
GO:0048365  Rac GTPase binding
GO:0004784  superoxide dismutase activity
GO:0008270  zinc ion binding