spleen tyrosine kinase

詳細情報を見る

同義遺伝子名

spleen tyrosine kinase, Spleen tyrosine kinase, SYK, Tyrosine-protein kinase SYK

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:9.50 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:61.30 脊柱:- 網膜:237.30 目:29.40 動脈:- 静脈:- リンパ節:242.60 末梢血:255.10 脾臓:94.50 胸腺:167.50 骨髄:649.50 脂肪:- 骨:64 皮膚:86.40
GeneChip nodata
CAGE 大脳:1.90 小脳:- 脳幹:2.62 脳梁:2.74 松果体:0.90 末梢神経:- 脊柱:2.94 網膜:- 目:- 動脈:2.48 静脈:4.08 リンパ節:4.24 末梢血:- 脾臓:4.26 胸腺:3.96 骨髄:- 脂肪:2.81 骨:- 皮膚:-
RNA-seq nodata
EST 子宮:45.60 胎盤:43.70 前立腺:- 卵巣:- 精巣:38.90 心臓:- 骨格筋:- 食道:- 胃:21.20 腸:64.80 結腸:101.80     肝臓:73.90        肺:68.40    膀胱:125.60 腎臓:31.20 下垂体:- 甲状腺:- 副腎:- 膵臓:8.90 乳腺:18.60 唾液腺:-
GeneChip nodata
CAGE 子宮:1.91 胎盤:2.37 前立腺:2.28 卵巣:1.79 精巣:2.28 心臓:2.22 骨格筋:0.91 食道:2.87 胃:- 腸:3.44 結腸:3.37     肝臓:1.51    肺:3.33 膀胱:2.21 腎臓:2.41 下垂体:1.54 甲状腺:3.42 副腎:- 膵臓:2.54 乳腺:2.79 唾液腺:2.43
RNA-seq nodata

IDs

Refseq ID NR_024155
Gene ID 6850
Unigene ID Hs.371720
Probe set ID -
Ensembl ID -
GTEx ID -

オーソログ対応遺伝子

マウス [0]  
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1423621
1569106
1689310
1998697
2065070
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3472906
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0002250  adaptive immune response
GO:0001525  angiogenesis
GO:0050853  B cell receptor signaling pathway
GO:0043366  beta selection
GO:0007596  blood coagulation
GO:0048514  blood vessel morphogenesis
GO:0008283  cell proliferation
GO:0071226  cellular response to molecule of fungal origin
GO:0042742  defense response to bacterium
GO:0007167  enzyme linked receptor protein signaling pathway
GO:0045087  innate immune response
GO:0007229  integrin-mediated signaling pathway
GO:0002366  leukocyte activation during immune response
GO:0007159  leukocyte adhesion
GO:0019370  leukotriene biosynthetic process
GO:0001945  lymph vessel development
GO:0002281  macrophage activation during immune response
GO:0002283  neutrophil activation during immune response
GO:0030593  neutrophil chemotaxis
GO:0009887  organ morphogenesis
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0030168  platelet activation
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0045579  positive regulation of B cell differentiation
GO:0045780  positive regulation of bone resorption
GO:0050850  positive regulation of calcium-mediated signaling
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0050715  positive regulation of cytokine secretion
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0045425  positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
GO:0045401  positive regulation of interleukin-3 biosynthetic process
GO:0043306  positive regulation of mast cell degranulation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0070372  regulation of ERK1 and ERK2 cascade
GO:0043313  regulation of neutrophil degranulation
GO:0050764  regulation of phagocytosis
GO:0010543  regulation of platelet activation
GO:0032928  regulation of superoxide release
GO:0002554  serotonin secretion by platelet
GO:0019048  virus-host interaction

Cellular Component

GO:0019815  B cell receptor complex
GO:0005829  cytosol
GO:0032009  early phagosome
GO:0005886  plasma membrane
GO:0042101  T cell receptor complex

Molecular Function

GO:0005524  ATP binding
GO:0005178  integrin binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004713  protein tyrosine kinase activity
GO:0004716  receptor signaling protein tyrosine kinase activity