mitogen-activated protein kinase kinase kinase 7

同義遺伝子名

Transforming growth factor-beta-activated kinase 1, TAK1, TGF-beta-activated kinase 1, mitogen-activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, TGF1a, MAP3K7

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:6.55

小脳:6.23

脳幹:6.84

脳梁:7.43

松果体:-

末梢神経:6.28

脊柱:6.90

網膜:-

目:-

動脈:6

静脈:5.57

リンパ節:6.79

末梢血:-

脾臓:7.41

胸腺:7.60

骨髄:6.25

脂肪:6.33

骨:-

皮膚:6.30

CAGE

大脳:3.46

小脳:-

脳幹:3.53

脳梁:3.23

松果体:3.86

末梢神経:-

脊柱:3.62

網膜:-

目:-

動脈:3.36

静脈:3.34

リンパ節:3.36

末梢血:-

脾臓:3.52

胸腺:3.64

骨髄:-

脂肪:3.10

骨:-

皮膚:-

RNA-seq

大脳:1.97

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.06

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.42

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:7.02

胎盤:6.90

前立腺:7

卵巣:7.07

精巣:6.54

心臓:6.14

骨格筋:6.26

食道:6.31

胃:6.30

腸:5.66

結腸:5.16

肝臓:6.15

肺:6.28

膀胱:-

腎臓:5.75

下垂体:6.68

甲状腺:6.92

副腎:6.44

膵臓:4.98

乳腺:6.79

唾液腺:5.99

CAGE

子宮:3.26

胎盤:3.50

前立腺:3.32

卵巣:3.25

精巣:3.25

心臓:3.42

骨格筋:3.28

食道:3.00

胃:-

腸:3.03

結腸:3.14

肝臓:2.83

肺:3.39

膀胱:3.14

腎臓:3.04

下垂体:3.65

甲状腺:3.17

副腎:-

膵臓:2.90

乳腺:3.54

唾液腺:2.50

RNA-seq

子宮:-

胎盤:-

前立腺:2.95

卵巣:3.14

精巣:3.06

心臓:3.20

骨格筋:2.26

食道:-

胃:-

腸:-

結腸:2.24

肝臓:0.28

肺:2.63

膀胱:-

腎臓:0.99

下垂体:-

甲状腺:1.87

副腎:2.89

膵臓:-

乳腺:2.78

唾液腺:-

IDs

Refseq ID	NM_003188
Gene ID	6885
Unigene ID	-
Probe set ID	206854_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000135341
GTEx ID	ENSG00000135341

オーソログ対応遺伝子

マウス[8]	NM_009316, NM_172688
ラット[1]	NM_001107920, NM_172688

染色体

6q15 [91,223,292 - 91,296,786]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR015786	Mitogen activated protein kinase kinase kinase-related
IPR017421	Mitogen-activated protein kinase kinase kinase 7
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0000186	activation of MAPKK activity
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0001525	angiogenesis
GO:0006915	apoptosis
GO:0043966	histone H3 acetylation
GO:0007249	I-kappaB kinase/NF-kappaB cascade
GO:0007252	I-kappaB phosphorylation
GO:0045087	innate immune response
GO:0007254	JNK cascade
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0001841	neural tube formation
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032743	positive regulation of interleukin-2 production
GO:0046330	positive regulation of JNK cascade
GO:0043507	positive regulation of JUN kinase activity
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0050870	positive regulation of T cell activation
GO:0002726	positive regulation of T cell cytokine production
GO:0051403	stress-activated MAPK cascade
GO:0050852	T cell receptor signaling pathway
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
GO:0005829	cytosol
GO:0010008	endosome membrane
GO:0008385	IkappaB kinase complex
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0000287	magnesium ion binding
GO:0004708	MAP kinase kinase activity
GO:0004709	MAP kinase kinase kinase activity
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity

mitogen-activated protein kinase kinase kinase 7

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function