transforming growth factor, beta 2

同義遺伝子名

Polyergin, TGFbeta2, TGF beta2, transforming growth factor, beta 2, TGF beta(2), G-TSF, BSC-1 cell growth inhibitor, TGFB2, TGF-beta-2, MGC116892, Cetermin, TGF beta 2, TGF-beta2, Transforming growth factor beta-2 precursor, TGFb2, Glioblastoma-derived T-cell suppressor factor

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:41.50

小脳:50.40

脳幹:-

脳梁:262.50

松果体:-

末梢神経:245.40

脊柱:-

網膜:237.30

目:58.80

動脈:30

静脈:-

リンパ節:-

末梢血:-

脾臓:37.80

胸腺:-

骨髄:-

脂肪:-

骨:89.60

皮膚:76.80

GeneChip

大脳:3.11

小脳:3.16

脳幹:3.09

脳梁:3.14

松果体:-

末梢神経:2.92

脊柱:3.05

網膜:-

目:-

動脈:3.05

静脈:3.50

リンパ節:2.98

末梢血:-

脾臓:2.87

胸腺:2.89

骨髄:3.21

脂肪:3

骨:-

皮膚:3.28

CAGE

大脳:4.23

小脳:-

脳幹:3.74

脳梁:4.28

松果体:3.31

末梢神経:-

脊柱:5.39

網膜:-

目:-

動脈:4.55

静脈:3.04

リンパ節:1.13

末梢血:-

脾臓:2.16

胸腺:0.91

骨髄:-

脂肪:1.97

骨:-

皮膚:-

RNA-seq

大脳:3.64

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.52

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.65

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:54.70

胎盤:25.50

前立腺:33.80

卵巣:-

精巣:-

心臓:12.80

骨格筋:-

食道:-

胃:-

腸:-

結腸:8.50

肝臓:21.10

肺:63.50

膀胱:125.60

腎臓:-

下垂体:-

甲状腺:-

副腎:50.80

膵臓:-

乳腺:232.30

唾液腺:-

GeneChip

子宮:3.08

胎盤:2.81

前立腺:2.94

卵巣:2.96

精巣:2.71

心臓:3.23

骨格筋:2.98

食道:2.88

胃:3.02

腸:2.99

結腸:3.21

肝臓:2.93

肺:3.10

膀胱:-

腎臓:3.06

下垂体:2.77

甲状腺:2.80

副腎:3.03

膵臓:3.34

乳腺:2.99

唾液腺:3.01

CAGE

子宮:4.22

胎盤:3.60

前立腺:4.31

卵巣:3.13

精巣:2.21

心臓:3.17

骨格筋:3.71

食道:2.65

胃:-

腸:1.82

結腸:2.17

肝臓:1.16

肺:3.74

膀胱:3.48

腎臓:2.26

下垂体:3.49

甲状腺:2.96

副腎:-

膵臓:2.48

乳腺:2.69

唾液腺:4.04

RNA-seq

子宮:-

胎盤:-

前立腺:2.22

卵巣:2.12

精巣:1.95

心臓:0.75

骨格筋:1.20

食道:-

胃:-

腸:-

結腸:1.70

肝臓:0.11

肺:3.33

膀胱:-

腎臓:1.20

下垂体:-

甲状腺:2.49

副腎:1.63

膵臓:-

乳腺:1.88

唾液腺:-

IDs

Refseq ID	NM_003238
Gene ID	7042
Unigene ID	Hs.133379
Probe set ID	209908_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000092969
GTEx ID	ENSG00000092969

オーソログ対応遺伝子

マウス[3]	NM_009367
ラット[1]	NM_031131

染色体

1q41 [218,519,577 - 218,617,961]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001111	Transforming growth factor beta (TGFb), N-terminal
IPR015618	Transforming growth factor beta 3
IPR003911	Transforming growth factor beta TGFb
IPR003940	Transforming growth factor, beta 2
IPR016319	Transforming growth factor-beta
IPR015615	Transforming growth factor-beta-related

遺伝子オントロジー (GO ID)

Biological Process

GO:0032147	activation of protein kinase activity
GO:0006924	activation-induced cell death of T cells
GO:0001525	angiogenesis
GO:0007411	axon guidance
GO:0007596	blood coagulation
GO:0001974	blood vessel remodeling
GO:0060317	cardiac epithelial to mesenchymal transition
GO:0060038	cardiac muscle cell proliferation
GO:0010002	cardioblast differentiation
GO:0001502	cartilage condensation
GO:0042637	catagen
GO:0007050	cell cycle arrest
GO:0008219	cell death
GO:0016049	cell growth
GO:0016477	cell migration
GO:0000902	cell morphogenesis
GO:0008283	cell proliferation
GO:0045216	cell-cell junction organization
GO:0007267	cell-cell signaling
GO:0030199	collagen fibril organization
GO:0042416	dopamine biosynthetic process
GO:0009790	embryonic development
GO:0048566	embryonic gut development
GO:0001837	epithelial to mesenchymal transition
GO:0030198	extracellular matrix organization
GO:0001654	eye development
GO:0060325	face morphogenesis
GO:0048699	generation of neurons
GO:0008347	glial cell migration
GO:0001942	hair follicle development
GO:0031069	hair follicle morphogenesis
GO:0007507	heart development
GO:0003007	heart morphogenesis
GO:0030097	hemopoiesis
GO:0006917	induction of apoptosis
GO:0022601	menstrual cycle phase
GO:0010693	negative regulation of alkaline phosphatase activity
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0050777	negative regulation of immune response
GO:0010936	negative regulation of macrophage cytokine production
GO:0048666	neuron development
GO:0048663	neuron fate commitment
GO:0030593	neutrophil chemotaxis
GO:0042476	odontogenesis
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0051891	positive regulation of cardioblast differentiation
GO:0051795	positive regulation of catagen
GO:0033630	positive regulation of cell adhesion mediated by integrin
GO:0045787	positive regulation of cell cycle
GO:0051781	positive regulation of cell division
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0010634	positive regulation of epithelial cell migration
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0010628	positive regulation of gene expression
GO:0045823	positive regulation of heart contraction
GO:0050778	positive regulation of immune response
GO:0045726	positive regulation of integrin biosynthetic process
GO:0043525	positive regulation of neuron apoptosis
GO:0045778	positive regulation of ossification
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0050714	positive regulation of protein secretion
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0006468	protein amino acid phosphorylation
GO:0032909	regulation of transforming growth factor-beta2 production
GO:0042493	response to drug
GO:0001666	response to hypoxia
GO:0032570	response to progesterone stimulus
GO:0009611	response to wounding
GO:0007435	salivary gland morphogenesis
GO:0007184	SMAD protein nuclear translocation
GO:0048103	somatic stem cell division
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0042060	wound healing

Cellular Component

GO:0030424	axon
GO:0043025	cell soma
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0031093	platelet alpha granule lumen

Molecular Function

GO:0001540	beta-amyloid binding
GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0005160	transforming growth factor beta receptor binding
GO:0005114	type II transforming growth factor beta receptor binding

transforming growth factor, beta 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function