toll-like receptor 3

詳細情報を見る

同義遺伝子名

Toll-like receptor 3 precursor, CD283, TLR3, toll-like receptor 3, CD283 antigen

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:3.27 小脳:3.10 脳幹:3.30 脳梁:3.61 松果体:- 末梢神経:3.74 脊柱:3.58 網膜:- 目:- 動脈:3.68 静脈:3.56 リンパ節:3.46 末梢血:- 脾臓:3.87 胸腺:3.43 骨髄:3.34 脂肪:4.22 骨:- 皮膚:3.69
CAGE 大脳:1.58 小脳:- 脳幹:1.81 脳梁:1.84 松果体:2.46 末梢神経:- 脊柱:2.42 網膜:- 目:- 動脈:2.41 静脈:1.98 リンパ節:1.44 末梢血:- 脾臓:2.55 胸腺:1.12 骨髄:- 脂肪:3.05 骨:- 皮膚:-
RNA-seq 大脳:0.47 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.33 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.49 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.06 胎盤:7.41 前立腺:4.36 卵巣:4.30 精巣:4.04 心臓:3.79 骨格筋:3.33 食道:4.10 胃:3.96 腸:4.13 結腸:3.71 肝臓:3.96 肺:4.14 膀胱:- 腎臓:4.05 下垂体:3.49 甲状腺:3.90 副腎:4.09 膵臓:3.85 乳腺:3.97 唾液腺:4.05
CAGE 子宮:2.57 胎盤:4.30 前立腺:3.06 卵巣:2.78 精巣:1.35 心臓:2.35 骨格筋:1.56 食道:3.13 胃:- 腸:4.04 結腸:2.76     肝臓:2.59    肺:3.33 膀胱:2.63 腎臓:3.05 下垂体:1.74 甲状腺:2.97 副腎:- 膵臓:1.87 乳腺:2.99 唾液腺:2.31
RNA-seq 子宮:- 胎盤:- 前立腺:2.46 卵巣:2.10 精巣:1.62 心臓:1.02 骨格筋:0.57 食道:- 胃:- 腸:- 結腸:2.01     肝臓:0.96        肺:2.09    膀胱:- 腎臓:2.38 下垂体:- 甲状腺:1.90 副腎:1.67 膵臓:- 乳腺:2.82 唾液腺:-

IDs

Refseq ID NM_003265
Gene ID 7098
Unigene ID -
Probe set ID 206271_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164342
GTEx ID ENSG00000164342

オーソログ対応遺伝子

マウス[2]  NM_126166
ラット[1]  NM_198791

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9435236
10066798
10426995
10820283
11561001
11607032
11782555
12054664
12133979
12477932
12509442
12539043
12609980
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12672806
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14575692
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15107846
15119015
15153468
15212709
15226270
15315972
15340161
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15502848
15579900
15652398
15731229
15737993
15767394
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15845391
15935884
15961631
15972671
16029432
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16399790
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16482523
16484229
16533755
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16847112
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16950283
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17085778
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24791904

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0071260  cellular response to mechanical stimulus
GO:0042742  defense response to bacterium
GO:0051607  defense response to virus
GO:0009597  detection of virus
GO:0006972  hyperosmotic response
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0007252  I-kappaB phosphorylation
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0045671  negative regulation of osteoclast differentiation
GO:0045080  positive regulation of chemokine biosynthetic process
GO:0032722  positive regulation of chemokine production
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050729  positive regulation of inflammatory response
GO:0045356  positive regulation of interferon-alpha biosynthetic process
GO:0045359  positive regulation of interferon-beta biosynthetic process
GO:0032728  positive regulation of interferon-beta production
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0032735  positive regulation of interleukin-12 production
GO:0032755  positive regulation of interleukin-6 production
GO:0032757  positive regulation of interleukin-8 production
GO:0046330  positive regulation of JNK cascade
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0034123  positive regulation of toll-like receptor signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032760  positive regulation of tumor necrosis factor production
GO:0034346  positive regulation of type III interferon production
GO:0043330  response to exogenous dsRNA
GO:0007165  signal transduction
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005789  endoplasmic reticulum membrane
GO:0010008  endosome membrane
GO:0000139  Golgi membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane

Molecular Function

GO:0003725  double-stranded RNA binding
GO:0004872  receptor activity
GO:0004888  transmembrane receptor activity