tumor necrosis factor, alpha-induced protein 3

詳細情報を見る

同義遺伝子名

TNFA1P2, MGC104522, tumor necrosis factor, alpha-induced protein 3, Tumor necrosis factor, alpha-induced protein 3, A20, Putative DNA-binding protein A20, MGC138687, TNFAIP3, OTUD7C, Zinc finger protein A20, MGC138688

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:5.86 小脳:5.66 脳幹:6.03 脳梁:6.03 松果体:- 末梢神経:7.25 脊柱:7.53 網膜:- 目:- 動脈:8.08 静脈:9.60 リンパ節:9.72 末梢血:- 脾臓:9.41 胸腺:9.23 骨髄:8.05 脂肪:8.69 骨:- 皮膚:8.39
CAGE 大脳:1.38 小脳:- 脳幹:1.80 脳梁:2.09 松果体:2.00 末梢神経:- 脊柱:2.34 網膜:- 目:- 動脈:3.76 静脈:4.00 リンパ節:4.31 末梢血:- 脾臓:4.01 胸腺:4.25 骨髄:- 脂肪:4.14 骨:- 皮膚:-
RNA-seq 大脳:1.28 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.14 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.21 骨:- 皮膚:-
EST nodata
GeneChip 子宮:7.85 胎盤:8.53 前立腺:8.08 卵巣:8.82 精巣:7.62 心臓:7.64 骨格筋:6.98 食道:7.44 胃:8.18 腸:8.03 結腸:8.32 肝臓:7.81 肺:10.48 膀胱:- 腎臓:6.79 下垂体:6.68 甲状腺:7.59 副腎:8.11 膵臓:7.08 乳腺:8.08 唾液腺:7.15
CAGE 子宮:2.75 胎盤:3.40 前立腺:3.50 卵巣:4.41 精巣:2.98 心臓:3.28 骨格筋:2.92 食道:3.35 胃:- 腸:3.61 結腸:3.10     肝臓:2.76    肺:4.58 膀胱:3.94 腎臓:2.72 下垂体:2.12 甲状腺:2.13 副腎:- 膵臓:2.66 乳腺:3.71 唾液腺:2.12
RNA-seq 子宮:- 胎盤:- 前立腺:4.03 卵巣:4.88 精巣:3.26 心臓:1.33 骨格筋:2.16 食道:- 胃:- 腸:- 結腸:2.75     肝臓:1.33        肺:5.50    膀胱:- 腎臓:1.96 下垂体:- 甲状腺:2.29 副腎:4.31 膵臓:- 乳腺:2.53 唾液腺:-

IDs

Refseq ID NM_006290
Gene ID 7128
Unigene ID -
Probe set ID 202644_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118503
GTEx ID ENSG00000118503

オーソログ対応遺伝子

マウス[2]  NM_001166402, NM_009397
ラット[2]  NM_001166402, NM_009397

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2118515
2406243
8663499
8692885
8702721
8797804
9299557
9882303
9928991
10385526
10435631
10544141
10755617
11009421
11389905
11390377
11463333
11573245
11594795
12080044
12167698
12477932
12586352
12794157
12885753
12965196
14574404
14748687
14754897
15142865
15169888
15231748
15251990
15258597
15474016
15489334
15601843
15661910
15862966
16164629
16306043
16344560
16474993
16684768
16816117
16824518
16936197
17081983
17088249
17259397
17297453
17886247
17953374
17961127
17962196
17982456
18029035
18029348
18164316
18223652
18246070
18329387
18349075
18794853
18813897
18814951
19060883
19110536
19124729
19131965
19152111
19165918
19165919
19169254
19240061
19258598
19262574
19285159
19292917
19336370
19344623
19366996
19380636
19380639
19387456
19412163
19453261
19492975
19494296
19565500
19608751
19615732
19617629
19643665
19648161
19774492
19838193
19851077
19879194
19902201
19907439
19912257
19913121
19948975
20032510
20049410
20112363
20176734
20186265
20190752
20231195
20233754
20304918
20353580
20392859
20430393
20439292
20444755
20448643
20453841
20453842
20483768
20501938
20511617
20533286
20585109
20617138
20622874
20628086
20628624
20669229
20800603
20804738
20822710
20849588
20852893
20921970
20936779
20953190
20962850
21048031
21095585
21111841
21127049
21139048
21208380
21220427
21266526
21326317
21336280
21406721
21437236
21531730
21566404
21604024
21625233
21740805
21763284
21787353
21795344
21885437
21890473
21906983
21963094
21964925
21968712
21988832
22019834
22031828
22087647
22093807
22099304
22127930
22207688
22285182
22397314
22402800
22461193
22488580
22505724
22507528
22525270
22585859
22586175
22623711
22634524
22733818
22843550
22898832
22924496
22925894
22936803
22939624
23000965
23002441
23018911
23032186
23032187
23039325
23054742
23105109
23114873
23128233
23148088
23161053
23164641
23247143
23249958
23273568
23327292
23418597
23425151
23463012
23471665
23555688
23609450
23635951
23671587
23740937
23901138
24008839
24023622
24028082
24039598
24055365
24097066
24099634
24159176
24219294
24357803
24449572
24491438
24500711
24713261

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0001922  B-1 B cell homeostasis
GO:0070301  cellular response to hydrogen peroxide
GO:0071222  cellular response to lipopolysaccharide
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0043066  negative regulation of apoptosis
GO:0050869  negative regulation of B cell activation
GO:0045779  negative regulation of bone resorption
GO:0002677  negative regulation of chronic inflammatory response
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050728  negative regulation of inflammatory response
GO:0045824  negative regulation of innate immune response
GO:0032691  negative regulation of interleukin-1 beta production
GO:0032703  negative regulation of interleukin-2 production
GO:0032715  negative regulation of interleukin-6 production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0070429  negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070433  negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0031397  negative regulation of protein ubiquitination
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0034136  negative regulation of toll-like receptor 2 signaling pathway
GO:0034140  negative regulation of toll-like receptor 3 signaling pathway
GO:0034144  negative regulation of toll-like receptor 4 signaling pathway
GO:0034148  negative regulation of toll-like receptor 5 signaling pathway
GO:0032720  negative regulation of tumor necrosis factor production
GO:0032480  negative regulation of type I interferon production
GO:0070423  nucleotide-binding oligomerization domain containing signaling pathway
GO:0045732  positive regulation of protein catabolic process
GO:0016579  protein deubiquitination
GO:0070936  protein K48-linked ubiquitination
GO:0070536  protein K63-linked deubiquitination
GO:0051259  protein oligomerization
GO:0006508  proteolysis
GO:0050691  regulation of defense response to virus by host
GO:0002634  regulation of germinal center formation
GO:0002237  response to molecule of bacterial origin
GO:0032495  response to muramyl dipeptide

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005764  lysosome
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0019900  kinase binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0043621  protein self-association
GO:0043130  ubiquitin binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004842  ubiquitin-protein ligase activity
GO:0004843  ubiquitin-specific protease activity
GO:0008270  zinc ion binding