topoisomerase (DNA) II alpha 170kDa

詳細情報を見る

同義遺伝子名

TOP2, DNA topoisomerase 2-alpha, topoisomerase (DNA) II alpha 170kDa, DNA topoisomerase II, alpha isozyme, TOP2A, topoisomerase (DNA) II alpha (170kD), TP2A

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:47.40 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:30.70 脊柱:- 網膜:- 目:29.40 動脈:149.90 静脈:- リンパ節:262.90 末梢血:54.70 脾臓:56.70 胸腺:154.60 骨髄:19.70 脂肪:40.30 骨:25.60 皮膚:57.60
GeneChip nodata
CAGE 大脳:0.11 小脳:- 脳幹:0.25 脳梁:0.43 松果体:0.81 末梢神経:- 脊柱:1.22 網膜:- 目:- 動脈:0.87 静脈:3.02 リンパ節:2.78 末梢血:- 脾臓:2.80 胸腺:5.68 骨髄:- 脂肪:1.93 骨:- 皮膚:-
RNA-seq nodata
EST 子宮:18.20 胎盤:29.10 前立腺:- 卵巣:37.30 精巣:220.60 心臓:140.50 骨格筋:- 食道:- 胃:127.50 腸:129.60 結腸:50.90     肝臓:232.20        肺:78.20    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:50.80 膵臓:- 乳腺:37.20 唾液腺:-
GeneChip nodata
CAGE 子宮:1.80 胎盤:3.13 前立腺:1.14 卵巣:1.06 精巣:4.34 心臓:1.24 骨格筋:0.52 食道:3.18 胃:- 腸:3.07 結腸:3.17     肝臓:0.26    肺:2.43 膀胱:0.69 腎臓:1.24 下垂体:0.10 甲状腺:0.28 副腎:- 膵臓:0.94 乳腺:2.19 唾液腺:1.00
RNA-seq nodata

IDs

Refseq ID NM_001067000
Gene ID 7153
Unigene ID Hs.156346
Probe set ID -
Ensembl ID -
GTEx ID -

オーソログ対応遺伝子

マウス [0]  
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1309226
1373318
1652758
2556712
2836804
2845399
6267071
7499337
7585537
7635160
7961967
7980433
8166723
8387155
8393377
8710863
8939955
9049244
9795238
9804834
10095062
10207078
10393912
10465010
10473615
10646863
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11862483
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12014628
12078518
12079377
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12356743
12393188
12429798
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12429910
12477932
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12569090
12646164
12646941
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14566826
14596941
14632727
14702039
14759373
14978217
14989736
14991576
14996935
15034300
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15044480
15126503
15182198
15201855
15302935
15375522
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15491148
15504738
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15635413
15809708
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15965487
16009940
16053917
16091284
16114891
16139951
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17081983
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18062778
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24332808
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24778252
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030263  apoptotic chromosome condensation
GO:0007059  chromosome segregation
GO:0006266  DNA ligation
GO:0006281  DNA repair
GO:0006260  DNA replication
GO:0006265  DNA topological change
GO:0006261  DNA-dependent DNA replication
GO:0040016  embryonic cleavage
GO:0000278  mitotic cell cycle
GO:0006312  mitotic recombination
GO:0048015  phosphoinositide-mediated signaling
GO:0043065  positive regulation of apoptosis
GO:0045870  positive regulation of retroviral genome replication
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045070  positive regulation of viral genome replication
GO:0000712  resolution of meiotic recombination intermediates
GO:0006974  response to DNA damage stimulus
GO:0000819  sister chromatid segregation

Cellular Component

GO:0005814  centriole
GO:0009330  DNA topoisomerase complex (ATP-hydrolyzing)
GO:0000228  nuclear chromosome
GO:0009295  nucleoid
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0043234  protein complex
GO:0000795  synaptonemal complex
GO:0019035  viral integration complex

Molecular Function

GO:0005524  ATP binding
GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0003918  DNA topoisomerase (ATP-hydrolyzing) activity
GO:0008094  DNA-dependent ATPase activity
GO:0008144  drug binding
GO:0019899  enzyme binding
GO:0042826  histone deacetylase binding
GO:0000287  magnesium ion binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0005080  protein kinase C binding
GO:0043130  ubiquitin binding