tumor protein p73

詳細情報を見る

同義遺伝子名

Tumor protein p73, p53-like transcription factor, TP73, P73, tumor protein p73, p53-related protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:4.50 小脳:4.58 脳幹:4.60 脳梁:4.44 松果体:- 末梢神経:4.19 脊柱:4.09 網膜:- 目:- 動脈:4.37 静脈:4.67 リンパ節:4.39 末梢血:- 脾臓:4.10 胸腺:4.22 骨髄:4.42 脂肪:4.54 骨:- 皮膚:4.87
CAGE 大脳:0.47 小脳:- 脳幹:0.06 脳梁:0.88 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.79 静脈:1.03 リンパ節:1.10 末梢血:- 脾臓:1.24 胸腺:0.74 骨髄:- 脂肪:0.26 骨:- 皮膚:-
RNA-seq 大脳:0.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.00 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.30 胎盤:4.49 前立腺:4.34 卵巣:4.47 精巣:4.21 心臓:4.35 骨格筋:4.79 食道:4.60 胃:4.18 腸:4.32 結腸:4.44 肝臓:4.08 肺:4.32 膀胱:- 腎臓:4.33 下垂体:4.25 甲状腺:4.25 副腎:4.41 膵臓:4.65 乳腺:4.21 唾液腺:4.50
CAGE 子宮:0.19 胎盤:0.59 前立腺:0.49 卵巣:0.92 精巣:1.62 心臓:0 骨格筋:0 食道:0.46 胃:- 腸:0.27 結腸:0.21     肝臓:0.71    肺:1.12 膀胱:0.09 腎臓:0.08 下垂体:0.19 甲状腺:0.06 副腎:- 膵臓:0 乳腺:0 唾液腺:1.39
RNA-seq 子宮:- 胎盤:- 前立腺:0 卵巣:0.42 精巣:0.00 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0.10    膀胱:- 腎臓:0 下垂体:- 甲状腺:0 副腎:0 膵臓:- 乳腺:0.00 唾液腺:-

IDs

Refseq ID NM_001126240
Gene ID 7161
Unigene ID -
Probe set ID 220804_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000078900
GTEx ID ENSG00000078900

オーソログ対応遺伝子

マウス[5]  NM_001126330, NM_001126331, NM_011642
ラット[1]  NM_001108696, NM_001126331, NM_011642

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9288759
9296498
9537234
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0007050  cell cycle arrest
GO:0034644  cellular response to UV
GO:0033326  cerebrospinal fluid secretion
GO:0048546  digestive tract morphogenesis
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006978  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0031571  G1/S DNA damage checkpoint
GO:0021766  hippocampus development
GO:0006954  inflammatory response
GO:0001822  kidney development
GO:0006298  mismatch repair
GO:0043508  negative regulation of JUN kinase activity
GO:0043524  negative regulation of neuron apoptosis
GO:0045665  negative regulation of neuron differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048666  neuron development
GO:0043065  positive regulation of apoptosis
GO:0045793  positive regulation of cell size
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009791  post-embryonic development
GO:0051262  protein tetramerization
GO:0001836  release of cytochrome c from mitochondria
GO:0006974  response to DNA damage stimulus
GO:0010332  response to gamma radiation
GO:0010243  response to organic nitrogen
GO:0010165  response to X-ray
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000785  chromatin
GO:0005829  cytosol
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003684  damaged DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding