TNF receptor-associated factor 6

詳細情報を見る

同義遺伝子名

TNF receptor-associated factor 6, RING finger protein 85, RNF85, MGC:3310, Interleukin 1 signal transducer, TRAF6

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:4.70

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:30.70

脊柱:-

網膜:-

目:5.90

動脈:-

静脈:-

リンパ節:-

末梢血:72.90

脾臓:-

胸腺:25.80

骨髄:-

脂肪:40.30

骨:-

皮膚:19.20

GeneChip

大脳:5.25

小脳:5.17

脳幹:5.08

脳梁:5.43

松果体:-

末梢神経:5.22

脊柱:5.35

網膜:-

目:-

動脈:5.47

静脈:5.44

リンパ節:5.43

末梢血:-

脾臓:5.69

胸腺:5.73

骨髄:5.51

脂肪:5.28

骨:-

皮膚:5.13

CAGE

大脳:2.85

小脳:-

脳幹:2.96

脳梁:2.91

松果体:2.94

末梢神経:-

脊柱:2.74

網膜:-

目:-

動脈:2.58

静脈:2.62

リンパ節:2.50

末梢血:-

脾臓:2.49

胸腺:2.98

骨髄:-

脂肪:2.70

骨:-

皮膚:-

RNA-seq

大脳:0.00

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.00

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.00

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:43.70

前立腺:-

卵巣:37.30

精巣:8.70

心臓:12.80

骨格筋:-

食道:-

胃:21.20

腸:-

結腸:17

肝臓:21.10

肺:9.80

膀胱:-

腎臓:10.40

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:5.43

胎盤:5.29

前立腺:5.19

卵巣:5.42

精巣:5.72

心臓:5.58

骨格筋:5.47

食道:5.64

胃:5.46

腸:5.38

結腸:5.51

肝臓:5.65

肺:5.38

膀胱:-

腎臓:5.55

下垂体:5.23

甲状腺:5.51

副腎:5.35

膵臓:5.53

乳腺:5.22

唾液腺:5.28

CAGE

子宮:2.50

胎盤:2.26

前立腺:2.45

卵巣:2.48

精巣:3.08

心臓:2.54

骨格筋:2.37

食道:2.44

胃:-

腸:2.75

結腸:2.11

肝臓:1.90

肺:2.33

膀胱:2.39

腎臓:2.66

下垂体:2.58

甲状腺:2.43

副腎:-

膵臓:2.41

乳腺:2.47

唾液腺:2.39

RNA-seq

子宮:-

胎盤:-

前立腺:0.00

卵巣:0.00

精巣:0.06

心臓:0.00

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:0.00

肝臓:0.00

肺:0.00

膀胱:-

腎臓:0.00

下垂体:-

甲状腺:0.00

副腎:0.28

膵臓:-

乳腺:0.00

唾液腺:-

IDs

Refseq ID	NM_145803
Gene ID	7189
Unigene ID	Hs.591983
Probe set ID	205558_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000175104
GTEx ID	ENSG00000175104

オーソログ対応遺伝子

マウス[3]	NM_009424
ラット [0]

染色体

11p12 [36,508,577 - 36,531,822]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR002083	MATH
IPR012227	TNF receptor-associated factor TRAF
IPR008974	TRAF-like

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0032147	activation of protein kinase activity
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453	bone resorption
GO:0048468	cell development
GO:0007249	I-kappaB kinase/NF-kappaB cascade
GO:0045087	innate immune response
GO:0070498	interleukin-1-mediated signaling pathway
GO:0007254	JNK cascade
GO:0031293	membrane protein intracellular domain proteolysis
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0043011	myeloid dendritic cell differentiation
GO:0043066	negative regulation of apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048011	nerve growth factor receptor signaling pathway
GO:0001843	neural tube closure
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0042475	odontogenesis of dentine-containing tooth
GO:0001503	ossification
GO:0030316	osteoclast differentiation
GO:0043065	positive regulation of apoptosis
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045084	positive regulation of interleukin-12 biosynthetic process
GO:0032743	positive regulation of interleukin-2 production
GO:0045410	positive regulation of interleukin-6 biosynthetic process
GO:0043507	positive regulation of JUN kinase activity
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045672	positive regulation of osteoclast differentiation
GO:0031398	positive regulation of protein ubiquitination
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0050870	positive regulation of T cell activation
GO:0002726	positive regulation of T cell cytokine production
GO:0042102	positive regulation of T cell proliferation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051865	protein autoubiquitination
GO:0006461	protein complex assembly
GO:0070534	protein K63-linked ubiquitination
GO:0000209	protein polyubiquitination
GO:0051023	regulation of immunoglobulin secretion
GO:0070555	response to interleukin-1
GO:0051403	stress-activated MAPK cascade
GO:0050852	T cell receptor signaling pathway
GO:0042088	T-helper 1 type immune response
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005938	cell cortex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0010008	endosome membrane
GO:0009898	internal side of plasma membrane
GO:0005811	lipid particle
GO:0031965	nuclear membrane
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0042826	histone deacetylase binding
GO:0031435	mitogen-activated protein kinase kinase kinase binding
GO:0005515	protein binding
GO:0043422	protein kinase B binding
GO:0019901	protein kinase binding
GO:0047485	protein N-terminus binding
GO:0004871	signal transducer activity
GO:0031996	thioesterase binding
GO:0031625	ubiquitin protein ligase binding
GO:0004842	ubiquitin-protein ligase activity
GO:0008270	zinc ion binding

TNF receptor-associated factor 6

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function