tumor necrosis factor (ligand) superfamily, member 4

同義遺伝子名

Glycoprotein Gp34, TNFSF4, CD252 antigen, CD252, TXGP1, CD134L, gp34, Tumor necrosis factor ligand superfamily member 4, OX4OL, TAX transcriptionally-activated glycoprotein 1, GP34, OX-40L, OX40 ligand, OX40L

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.60

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:11.80

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:12.90

骨髄:-

脂肪:-

骨:-

皮膚:9.60

GeneChip

大脳:4.61

小脳:4.69

脳幹:4.60

脳梁:4.64

松果体:-

末梢神経:4.60

脊柱:4.75

網膜:-

目:-

動脈:4.50

静脈:4.57

リンパ節:4.64

末梢血:-

脾臓:4.92

胸腺:5.39

骨髄:4.77

脂肪:4.65

骨:-

皮膚:4.38

CAGE

大脳:0.15

小脳:-

脳幹:0

脳梁:0.07

松果体:0

末梢神経:-

脊柱:0.09

網膜:-

目:-

動脈:0

静脈:0.59

リンパ節:0.95

末梢血:-

脾臓:1.18

胸腺:1.10

骨髄:-

脂肪:0.26

骨:-

皮膚:-

RNA-seq

大脳:0.65

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.99

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.34

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.61

胎盤:4.80

前立腺:5.19

卵巣:4.61

精巣:5.79

心臓:4.43

骨格筋:4.53

食道:4.36

胃:4.56

腸:4.53

結腸:4.32

肝臓:4.40

肺:4.49

膀胱:-

腎臓:4.50

下垂体:4.98

甲状腺:4.37

副腎:4.85

膵臓:4.46

乳腺:4.39

唾液腺:4.34

CAGE

子宮:0.09

胎盤:0.08

前立腺:0.27

卵巣:0.47

精巣:1.52

心臓:0.11

骨格筋:0

食道:0.26

胃:-

腸:0.33

結腸:0.04

肝臓:0

肺:0.45

膀胱:0.26

腎臓:0

下垂体:0

甲状腺:0

副腎:-

膵臓:0

乳腺:0.55

唾液腺:0

RNA-seq

子宮:-

胎盤:-

前立腺:1.27

卵巣:1.13

精巣:1.71

心臓:0.36

骨格筋:0.20

食道:-

胃:-

腸:-

結腸:0.38

肝臓:0.16

肺:0.92

膀胱:-

腎臓:0.74

下垂体:-

甲状腺:0.23

副腎:0.45

膵臓:-

乳腺:0.56

唾液腺:-

IDs

Refseq ID	NM_003326
Gene ID	7292
Unigene ID	Hs.181097
Probe set ID	207426_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000117586
GTEx ID	ENSG00000117586

オーソログ対応遺伝子

マウス[1]	NM_009452
ラット [0]

染色体

1q25.1 [173,152,873 - 173,176,452]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR006052	Tumor Necrosis Factor
IPR008983	Tumour necrosis factor-like

遺伝子オントロジー (GO ID)

Biological Process

GO:0002526	acute inflammatory response
GO:0071222	cellular response to lipopolysaccharide
GO:0071380	cellular response to prostaglandin E stimulus
GO:0008203	cholesterol metabolic process
GO:0002215	defense response to nematode
GO:0050710	negative regulation of cytokine secretion
GO:0032689	negative regulation of interferon-gamma production
GO:0032700	negative regulation of interleukin-17 production
GO:0045590	negative regulation of regulatory T cell differentiation
GO:0045626	negative regulation of T-helper 1 cell differentiation
GO:0043433	negative regulation of transcription factor activity
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0042104	positive regulation of activated T cell proliferation
GO:0046641	positive regulation of alpha-beta T cell proliferation
GO:0050871	positive regulation of B cell activation
GO:0043372	positive regulation of CD4-positive, alpha beta T cell differentiation
GO:0008284	positive regulation of cell proliferation
GO:0002891	positive regulation of immunoglobulin mediated immune response
GO:0051024	positive regulation of immunoglobulin secretion
GO:0050729	positive regulation of inflammatory response
GO:0032729	positive regulation of interferon-gamma production
GO:0032733	positive regulation of interleukin-10 production
GO:0032735	positive regulation of interleukin-12 production
GO:0032736	positive regulation of interleukin-13 production
GO:0032743	positive regulation of interleukin-2 production
GO:0032753	positive regulation of interleukin-4 production
GO:0032755	positive regulation of interleukin-6 production
GO:0043382	positive regulation of memory T cell differentiation
GO:0002726	positive regulation of T cell cytokine production
GO:0045630	positive regulation of T-helper 2 cell differentiation
GO:0002830	positive regulation of T-helper 2 type immune response
GO:0002819	regulation of adaptive immune response
GO:0050727	regulation of inflammatory response
GO:0042221	response to chemical stimulus
GO:0009615	response to virus
GO:0007165	signal transduction
GO:0042098	T cell proliferation

Cellular Component

GO:0009986	cell surface
GO:0005615	extracellular space
GO:0005887	integral to plasma membrane

Molecular Function

GO:0005125	cytokine activity
GO:0005102	receptor binding
GO:0005164	tumor necrosis factor receptor binding
GO:0032813	tumor necrosis factor receptor superfamily binding

tumor necrosis factor (ligand) superfamily, member 4

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function