chemokine (C-C motif) receptor 2

詳細情報を見る

同義遺伝子名

-

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:3.84 小脳:4.01 脳幹:3.85 脳梁:4.04 松果体:- 末梢神経:4.52 脊柱:3.94 網膜:- 目:- 動脈:4.50 静脈:4.34 リンパ節:5.42 末梢血:- 脾臓:6.19 胸腺:5.22 骨髄:6 脂肪:4.64 骨:- 皮膚:4.63
CAGE 大脳:0.14 小脳:- 脳幹:0.51 脳梁:0.29 松果体:0 末梢神経:- 脊柱:0.62 網膜:- 目:- 動脈:1.22 静脈:2.25 リンパ節:2.51 末梢血:- 脾臓:3.41 胸腺:1.20 骨髄:- 脂肪:0.63 骨:- 皮膚:-
RNA-seq 大脳:0.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.66 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.24 骨:- 皮膚:-
EST nodata
GeneChip 子宮:4.49 胎盤:3.91 前立腺:4.06 卵巣:4.55 精巣:3.78 心臓:4.10 骨格筋:4.07 食道:4.19 胃:4.71 腸:4.78 結腸:4.58 肝臓:4.39 肺:4.81 膀胱:- 腎臓:4.07 下垂体:4.06 甲状腺:4.35 副腎:3.89 膵臓:4.10 乳腺:4.52 唾液腺:4.30
CAGE 子宮:1.36 胎盤:0.95 前立腺:1.48 卵巣:0.86 精巣:0.61 心臓:0.64 骨格筋:0.30 食道:1.83 胃:- 腸:1.92 結腸:1.42     肝臓:0.78    肺:2.13 膀胱:0.69 腎臓:1.37 下垂体:0.24 甲状腺:0.76 副腎:- 膵臓:0.58 乳腺:0 唾液腺:1.75
RNA-seq 子宮:- 胎盤:- 前立腺:0.24 卵巣:0.70 精巣:0.61 心臓:0.41 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.18     肝臓:0.53        肺:0.90    膀胱:- 腎臓:0.71 下垂体:- 甲状腺:0.22 副腎:1.36 膵臓:- 乳腺:0.25 唾液腺:-

IDs

Refseq ID NM_001123041
Gene ID 729230
Unigene ID -
Probe set ID 206978_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000121807
GTEx ID ENSG00000121807

オーソログ対応遺伝子

マウス[6]  NM_009915, NM_009917
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

2834384
8048929
8146186
8530354
8884276
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001974  blood vessel remodeling
GO:0006874  cellular calcium ion homeostasis
GO:0006968  cellular defense response
GO:0019725  cellular homeostasis
GO:0070098  chemokine-mediated signaling pathway
GO:0006935  chemotaxis
GO:0019221  cytokine-mediated signaling pathway
GO:0002407  dendritic cell chemotaxis
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0006955  immune response
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0007259  JAK-STAT cascade
GO:0007194  negative regulation of adenylate cyclase activity
GO:0016525  negative regulation of angiogenesis
GO:0043310  negative regulation of eosinophil degranulation
GO:0002829  negative regulation of T-helper 2 type immune response
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0050729  positive regulation of inflammatory response
GO:0032729  positive regulation of interferon-gamma production
GO:0032743  positive regulation of interleukin-2 production
GO:0090026  positive regulation of monocyte chemotaxis
GO:0050870  positive regulation of T cell activation
GO:0010820  positive regulation of T cell chemotaxis
GO:0002827  positive regulation of T-helper 1 type immune response
GO:0042535  positive regulation of tumor necrosis factor biosynthetic process
GO:0010574  regulation of vascular endothelial growth factor production
GO:0009611  response to wounding
GO:0019048  virus-host interaction

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0043204  perikaryon
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0016493  C-C chemokine receptor activity
GO:0031727  CCR2 chemokine receptor binding
GO:0004950  chemokine receptor activity
GO:0042803  protein homodimerization activity