thymidylate synthetase

 詳細情報を見る

同義遺伝子名

HsT422, Tsase, thymidylate synthetase (TS), TSase, thymidylate synthetase, MGC88736, Thymidylate synthase, TMS, OK/SW-cl.29, TYMS

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:22.50 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:237.30 目:23.50 動脈:60 静脈:- リンパ節:20.20 末梢血:18.20 脾臓:37.80 胸腺:25.80 骨髄:39.40 脂肪:- 骨:64 皮膚:43.20
GeneChip nodata
CAGE 大脳:1.32 小脳:- 脳幹:1.57 脳梁:2.59 松果体:0.35 末梢神経:- 脊柱:1.15 網膜:- 目:- 動脈:0.79 静脈:2.83 リンパ節:2.18 末梢血:- 脾臓:2.01 胸腺:4.36 骨髄:- 脂肪:1.29 骨:- 皮膚:-
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:18.20 胎盤:94.70 前立腺:11.30 卵巣:111.80 精巣:77.90 心臓:25.50 骨格筋:- 食道:- 胃:63.70 腸:32.40 結腸:25.40     肝臓:137.20        肺:19.60    膀胱:- 腎臓:72.80 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:18.60 唾液腺:-
GeneChip nodata
CAGE 子宮:1.08 胎盤:2.74 前立腺:1.36 卵巣:0.60 精巣:2.94 心臓:0.83 骨格筋:0.17 食道:1.91 胃:- 腸:2.02 結腸:2.52     肝臓:0.96    肺:1.32 膀胱:0.87 腎臓:1.50 下垂体:0.19 甲状腺:0.28 副腎:- 膵臓:0.58 乳腺:0.90 唾液腺:0.62
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001071000
Gene ID 7298
Unigene ID Hs.592338
Probe set ID -
Ensembl ID -
GTEx ID -

オーソログ対応遺伝子

マウス [0]  
ラット [0]  

染色体

18p11.32  [657,604  -  673,578]

遺伝子ファミリー (Interpro ID)

IPR000398  Thymidylate synthase

Link to Pubmed  (Pubmed ID)

1720706
2243092
2532645
2656695
2987839
3839505
8125298
8449516
8845352
9148948
11102983
11251009
11251164
11278511
11316879
11329255
11445856
11697906
11747337
11799066
11804689
11937185
11989786
11992400
12018454
12067974
12084458
12084459
12084460
12084461
12084462
12147691
12215845
12220503
12239455
12466474
12477932
12530000
12576451
12576452
12604405
12640689
12684695
12706868
12782596
12845668
12859954
12907731
12972956
14519634
14519641
14576935
14578129
14586640
14656021
14702180
14745930
14760062
14967037
14970324
14977639
15093541
15115918
15161716
15198953
15213713
15231747
15244514
15251465
15259039
15260847
15284183
15316940
15355920
15386366
15386371
15457444
15459215
15489334
15504738
15510613
15571262
15571263
15571283
15579479
15585623
15598787
15677700
15682292
15713801
15735113
15736425
15788669
15797993
15817609
15897576
15930032
15952572
15953655
15985285
15993511
15999119
16030402
16045580
16051637
16077970
16079077
16130010
16132996
16141798
16162288
16182121
16188144
16219137
16234002
16242255
16259621
16284371
16317430
16328059
16328315
16333305
16334126
16365025
16424979
16447238
16456808
16467096
16575011
16580699
16596248
16609021
16617381
16622263
16675565
16722845
16723031
16773218
16920564
16929515
17000685
17018589
17065089
17181924
17187508
17201138
17203168
17220568
17273745
17290389
17311259
17317154
17367411
17369151
17372271
17377791
17385677
17395259
17410198
17417073
17439323
17449906
17454638
17512053
17546637
17549369
17551301
17581305
17596206
17655928
17659576
17661145
17684410
17684476
17688376
17716232
17854149
17891500
17971770
18095031
18098291
18174236
18177869
18192902
18203297
18221821
18245544
18267032
18274813
18281538
18285546
18299612
18322994
18336674
18365142
18370400
18381794
18406541
18427977
18430179
18448328
18458991
18498133
18505590
18510611
18540691
18584349
18589584
18593893
18597678
18600534
18607581
18629514
18635682
18636124
18642643
18669903
18676680
18676755
18677108
18704422
18722050
18728661
18781797
18785313
18830263
18855534
18976010
18983896
18985814
18988749
18989779
18990369
18992148
19020309
19020759
19020767
19048631
19064578
19074750
19082493
19147506
19154585
19159907
19161160
19162321
19170196
19190136
19295264
19306093
19307503
19332728
19339270
19339911
19374805
19384296
19426394
19427504
19444465
19460136
19471022
19493349
19513514
19546880
19568409
19571608
19619240
19621386
19625176
19632929
19636001
19651439
19672780
19692168
19722231
19724871
19738201
19748501
19750576
19751277
19774638
19822515
19837268
19850635
19858398
19858780
19885596
19888426
19898266
19913121
19917450
19956635
19998340
20012317
20047592
20061047
20101025
20112501
20122156
20151707
20165956
20177420
20180013
20216541
20235210
20237949
20306339
20310006
20331623
20368715
20371218
20372850
20372856
20381446
20385995
20387074
20447923
20453000
20458436
20501373
20504250
20515563
20530282
20531375
20544798
20565774
20570913
20571234
20580582
20615890
20628086
20628382
20628391
20634891
20638924
20647221
20647341
20651387
20665215
20670920
20714149
20714877
20734048
20737570
20815815
20819423
20824655
20837458
20932673
20944490
20962453
20966539
20970877
21036767
21043562
21048041
21057378
21064161
21111509
21131780
21139048
21167658
21188629
21206062
21245530
21254360
21262916
21269855
21282454
21321092
21347782
21362378
21460376
21463130
21471424
21550658
21570215
21603981
21605004
21618517
21643952
21716147
21730794
21788964
21811101
21824439
21848426
21890473
21900206
21906983
21919605
21947036
21948461
21956592
21963094
21965773
21987572
22006578
22074251
22110208
22143355
22166040
22172489
22233820
22270332
22307944
22384047
22388795
22397721
22407825
22486600
22496803
22502681
22505724
22551903
22576918
22580655
22593457
22623428
22641663
22713864
22763757
22819905
22825513
22863883
22866924
22882943
22887475
22895141
22901148
22938428
22939629
23000965
23098521
23148637
23217244
23249808
23263912
23336575
23350714
23468971
23523421
23645741
23652803
23675481
23710599
23722170
23726796
23736036
23810585
23838799
23903781
23930679
23968134
24040222
24067998
24100087
24123038
24347111
24590654
24654937
24800948
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007568  aging
GO:0051216  cartilage development
GO:0007623  circadian rhythm
GO:0009157  deoxyribonucleoside monophosphate biosynthetic process
GO:0048589  developmental growth
GO:0006281  DNA repair
GO:0006260  DNA replication
GO:0006231  dTMP biosynthetic process
GO:0006235  dTTP biosynthetic process
GO:0046078  dUMP metabolic process
GO:0000082  G1/S transition of mitotic cell cycle
GO:0019088  immortalization of host cell by virus
GO:0060574  intestinal epithelial cell maturation
GO:0000278  mitotic cell cycle
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006139  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0031100  organ regeneration
GO:0048015  phosphoinositide-mediated signaling
GO:0005976  polysaccharide metabolic process
GO:0006206  pyrimidine base metabolic process
GO:0046134  pyrimidine nucleoside biosynthetic process
GO:0000083  regulation of transcription involved in G1/S-phase of mitotic cell cycle
GO:0034097  response to cytokine stimulus
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0051593  response to folic acid
GO:0051384  response to glucocorticoid stimulus
GO:0046683  response to organophosphorus
GO:0032570  response to progesterone stimulus
GO:0009636  response to toxin
GO:0033189  response to vitamin A
GO:0046653  tetrahydrofolate metabolic process
GO:0019860  uracil metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005743  mitochondrial inner membrane
GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0048037  cofactor binding
GO:0008144  drug binding
GO:0005542  folic acid binding
GO:0003729  mRNA binding
GO:0000166  nucleotide binding
GO:0042803  protein homodimerization activity
GO:0004799  thymidylate synthase activity