nuclear receptor subfamily 1, group H, member 2

詳細情報を見る

同義遺伝子名

nuclear receptor subfamily 1, group H, member 2, NER, RIP15, Oxysterols receptor LXR-beta, NER-I, LXRB, Nuclear receptor NER, Nuclear orphan receptor LXR-beta, NR1H2, Liver X receptor beta, LXR-b, Ubiquitously-expressed nuclear receptor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:157.60 小脳:201.50 脳幹:- 脳梁:262.50 松果体:- 末梢神経:153.40 脊柱:- 網膜:- 目:182.20 動脈:179.90 静脈:- リンパ節:343.80 末梢血:419 脾臓:264.70 胸腺:180.40 骨髄:295.20 脂肪:242 骨:345.50 皮膚:105.60
GeneChip 大脳:6.81 小脳:6.74 脳幹:6.84 脳梁:6.93 松果体:- 末梢神経:6.62 脊柱:6.63 網膜:- 目:- 動脈:7.18 静脈:7.10 リンパ節:6.90 末梢血:- 脾臓:7 胸腺:6.49 骨髄:6.69 脂肪:6.97 骨:- 皮膚:6.67
CAGE 大脳:3.93 小脳:- 脳幹:4.08 脳梁:3.94 松果体:4.16 末梢神経:- 脊柱:4.18 網膜:- 目:- 動脈:4.22 静脈:4.03 リンパ節:3.75 末梢血:- 脾臓:3.87 胸腺:3.63 骨髄:- 脂肪:3.83 骨:- 皮膚:-
RNA-seq 大脳:3.35 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.08 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.65 骨:- 皮膚:-
EST 子宮:173.20 胎盤:178.50 前立腺:225.30 卵巣:74.50 精巣:108.20 心臓:89.40 骨格筋:140.60 食道:- 胃:191.20 腸:324 結腸:76.30     肝臓:84.40        肺:127.10    膀胱:376.80 腎臓:114.40 下垂体:- 甲状腺:1310 副腎:50.80 膵臓:53.30 乳腺:158 唾液腺:328.40
GeneChip 子宮:6.68 胎盤:6.48 前立腺:6.70 卵巣:6.66 精巣:6.85 心臓:6.99 骨格筋:7.16 食道:7.13 胃:6.78 腸:6.74 結腸:7 肝臓:6.80 肺:7.23 膀胱:- 腎臓:7.03 下垂体:6.40 甲状腺:7.05 副腎:7.12 膵臓:6.53 乳腺:6.95 唾液腺:6.80
CAGE 子宮:3.94 胎盤:4.09 前立腺:4.05 卵巣:3.93 精巣:4.02 心臓:4.16 骨格筋:4.38 食道:4.10 胃:- 腸:4.08 結腸:3.71     肝臓:4.03    肺:4.07 膀胱:4.11 腎臓:4.02 下垂体:3.55 甲状腺:3.99 副腎:- 膵臓:3.89 乳腺:3.56 唾液腺:3.90
RNA-seq 子宮:- 胎盤:- 前立腺:4.80 卵巣:4.04 精巣:4.41 心臓:3.57 骨格筋:4.57 食道:- 胃:- 腸:- 結腸:4.37     肝臓:3.18        肺:4.93    膀胱:- 腎臓:3.83 下垂体:- 甲状腺:4.86 副腎:4.58 膵臓:- 乳腺:3.92 唾液腺:-

IDs

Refseq ID NM_007121
Gene ID 7376
Unigene ID Hs.432976
Probe set ID 218215_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000131408
GTEx ID ENSG00000131408

オーソログ対応遺伝子

マウス[1]  NM_009473
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0044255  cellular lipid metabolic process
GO:0042632  cholesterol homeostasis
GO:0010467  gene expression
GO:0010887  negative regulation of cholesterol storage
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0032369  negative regulation of lipid transport
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0048550  negative regulation of pinocytosis
GO:0045861  negative regulation of proteolysis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010875  positive regulation of cholesterol efflux
GO:0032376  positive regulation of cholesterol transport
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0090108  positive regulation of high-density lipoprotein particle assembly
GO:0010884  positive regulation of lipid storage
GO:0051006  positive regulation of lipoprotein lipase activity
GO:0090187  positive regulation of pancreatic juice secretion
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010867  positive regulation of triglyceride biosynthetic process
GO:0048384  retinoic acid receptor signaling pathway
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005737  cytoplasm
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0005515  protein binding
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0008270  zinc ion binding