wingless-type MMTV integration site family, member 1

詳細情報を見る

同義遺伝子名

WNT1, Proto-oncogene protein Wnt-1 precursor, INT1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.84 小脳:3.74 脳幹:3.90 脳梁:3.63 松果体:- 末梢神経:3.69 脊柱:3.53 網膜:- 目:- 動脈:3.93 静脈:3.97 リンパ節:3.68 末梢血:- 脾臓:3.44 胸腺:3.53 骨髄:3.82 脂肪:3.93 骨:- 皮膚:4.10
CAGE 大脳:0.01 小脳:- 脳幹:0.03 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:0 リンパ節:0.17 末梢血:- 脾臓:0.09 胸腺:0 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.05 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.30 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:3.63 胎盤:3.80 前立腺:3.65 卵巣:3.62 精巣:3.76 心臓:3.81 骨格筋:3.97 食道:3.65 胃:3.55 腸:3.73 結腸:3.66 肝臓:3.71 肺:3.81 膀胱:- 腎臓:3.78 下垂体:3.78 甲状腺:3.55 副腎:3.69 膵臓:3.66 乳腺:3.73 唾液腺:3.67
CAGE 子宮:0 胎盤:1.63 前立腺:0 卵巣:0 精巣:0.04 心臓:0 骨格筋:0 食道:0 胃:- 腸:0.33 結腸:0.12     肝臓:0    肺:0 膀胱:0.09 腎臓:0 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.01 卵巣:0.02 精巣:0.67 心臓:0 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0.12    膀胱:- 腎臓:0 下垂体:- 甲状腺:0.00 副腎:0.24 膵臓:- 乳腺:0.01 唾液腺:-

IDs

Refseq ID NM_005430
Gene ID 7471
Unigene ID Hs.248164
Probe set ID 208570_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125084
GTEx ID ENSG00000125084

オーソログ対応遺伝子

マウス[1]  NM_021279
ラット[1]  NM_001105714

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060348  bone development
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0045165  cell fate commitment
GO:0007267  cell-cell signaling
GO:0071375  cellular response to peptide hormone stimulus
GO:0021551  central nervous system morphogenesis
GO:0021588  cerebellum formation
GO:0021536  diencephalon development
GO:0042770  DNA damage response, signal transduction
GO:0000578  embryonic axis specification
GO:0021797  forebrain anterior/posterior pattern formation
GO:0071425  hemopoietic stem cell proliferation
GO:0070365  hepatocyte differentiation
GO:0042472  inner ear morphogenesis
GO:0030901  midbrain development
GO:0022004  midbrain-hindbrain boundary maturation during brain development
GO:0007520  myoblast fusion
GO:0030514  negative regulation of BMP signaling pathway
GO:0022408  negative regulation of cell-cell adhesion
GO:0010812  negative regulation of cell-substrate adhesion
GO:0045599  negative regulation of fat cell differentiation
GO:0030512  negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030182  neuron differentiation
GO:0048664  neuron fate determination
GO:0031100  organ regeneration
GO:0008284  positive regulation of cell proliferation
GO:0048146  positive regulation of fibroblast proliferation
GO:0043568  positive regulation of insulin-like growth factor receptor signaling pathway
GO:0010592  positive regulation of lamellipodium assembly
GO:0045747  positive regulation of Notch signaling pathway
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009611  response to wounding
GO:0060061  Spemann organizer formation
GO:0021527  spinal cord association neuron differentiation
GO:0033077  T cell differentiation in the thymus
GO:0030579  ubiquitin-dependent SMAD protein catabolic process
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005796  Golgi lumen
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005125  cytokine activity
GO:0044212  DNA regulatory region binding
GO:0005109  frizzled binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0048018  receptor agonist activity