wingless-type MMTV integration site family, member 10B

 詳細情報を見る

同義遺伝子名

Protein Wnt-10b precursor, WNT10B, WNT-12, WNT12, Wnt-12

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:30.80 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.80 皮膚:9.60
GeneChip 大脳:6.77 小脳:6.15 脳幹:6.73 脳梁:6.21 松果体:- 末梢神経:6.12 脊柱:6.21 網膜:- 目:- 動脈:5.94 静脈:6.41 リンパ節:6.04 末梢血:- 脾臓:5.87 胸腺:5.26 骨髄:6.32 脂肪:6.33 骨:- 皮膚:5.77
CAGE 大脳:0.18 小脳:- 脳幹:0.22 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.18 静脈:0.96 リンパ節:0.03 末梢血:- 脾臓:0 胸腺:0.06 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:1.67 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.56 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.03 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:13 心臓:38.30 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.59 胎盤:5.86 前立腺:5.38 卵巣:5.56 精巣:5.66 心臓:6.51 骨格筋:6.60 食道:5.96 胃:6.18 腸:6.24 結腸:6.71 肝臓:6.28 肺:5.83 膀胱:- 腎臓:6.30 下垂体:6.09 甲状腺:5.67 副腎:6.23 膵臓:6.63 乳腺:5.69 唾液腺:6.52
CAGE 子宮:0 胎盤:0.81 前立腺:0.15 卵巣:0.07 精巣:0.16 心臓:0.23 骨格筋:0.30 食道:0.09 胃:- 腸:0.27 結腸:0.04     肝臓:0    肺:0 膀胱:0.33 腎臓:0 下垂体:0 甲状腺:0.06 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.53 卵巣:0.13 精巣:0.40 心臓:0.06 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.08     肝臓:0.00        肺:0.45    膀胱:- 腎臓:0.06 下垂体:- 甲状腺:0.16 副腎:0.50 膵臓:- 乳腺:0.37 唾液腺:-

詳細情報

IDs

Refseq ID NM_003394
Gene ID 7480
Unigene ID Hs.91985
Probe set ID 206213_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169884
GTEx ID ENSG00000169884

オーソログ対応遺伝子

マウス[1]  NM_011718
ラット [0]  

染色体

12q13.12  [49,359,123  -  49,365,546]

遺伝子ファミリー (Interpro ID)

IPR005816  Secreted growth factor Wnt protein
IPR005817  Wnt superfamily
IPR013302  Wnt-10 protein

Link to Pubmed  (Pubmed ID)

8167409
9121776
9284937
9441749
9787155
10937998
11350055
11713588
12437293
12477932
15135146
15489334
16344560
16477437
17761539
18465804
18515319
19016593
19056892
19075223
19453261
19458884
19913121
20579865
20628086
20628624
20635353
21321991
21554266
22041457
22118674
22189080
22890324
23104151
23135473
23307470
23325361
23900840
24211389

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060346  bone trabecula formation
GO:0007050  cell cycle arrest
GO:0045165  cell fate commitment
GO:0071320  cellular response to cAMP
GO:0071374  cellular response to parathyroid hormone stimulus
GO:0071300  cellular response to retinoic acid
GO:0002062  chondrocyte differentiation
GO:0000086  G2/M transition of mitotic cell cycle
GO:0071425  hemopoietic stem cell proliferation
GO:0006629  lipid metabolic process
GO:0014835  myoblast cell differentiation involved in skeletal muscle regeneration
GO:0050680  negative regulation of epithelial cell proliferation
GO:0045599  negative regulation of fat cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030182  neuron differentiation
GO:0051885  positive regulation of anagen
GO:0043065  positive regulation of apoptosis
GO:0030501  positive regulation of bone mineralization
GO:0008284  positive regulation of cell proliferation
GO:0030858  positive regulation of epithelial cell differentiation
GO:0010971  positive regulation of G2/M transition of mitotic cell cycle
GO:0045669  positive regulation of osteoblast differentiation
GO:0045899  positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0051091  positive regulation of transcription factor activity
GO:0050821  protein stabilization
GO:0032434  regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0048641  regulation of skeletal muscle tissue development
GO:0050909  sensory perception of taste
GO:0048741  skeletal muscle fiber development
GO:0007224  smoothened signaling pathway
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005109  frizzled binding
GO:0048018  receptor agonist activity