tumor necrosis factor (ligand) superfamily, member 11

詳細情報を見る

同義遺伝子名

hRANKL2, RANKL, CD254 antigen, sOdf, Osteoprotegerin ligand, Tumor necrosis factor ligand superfamily member 11, TNFSF11, ODF, CD254, OPGL, Osteoclast differentiation factor, TNF-related activation-induced cytokine, TRANCE

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:30.30 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:2.82 小脳:2.75 脳幹:2.89 脳梁:2.75 松果体:- 末梢神経:2.80 脊柱:2.76 網膜:- 目:- 動脈:3.01 静脈:2.98 リンパ節:4.84 末梢血:- 脾臓:3.06 胸腺:3.07 骨髄:2.91 脂肪:3.53 骨:- 皮膚:2.95
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:1.49 リンパ節:1.63 末梢血:- 脾臓:0.17 胸腺:0.83 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.35 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.07 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:- 唾液腺:-
GeneChip 子宮:2.84 胎盤:2.92 前立腺:2.88 卵巣:2.83 精巣:2.97 心臓:2.80 骨格筋:3.04 食道:2.91 胃:2.86 腸:3.06 結腸:2.93 肝臓:2.89 肺:2.79 膀胱:- 腎臓:2.73 下垂体:2.81 甲状腺:2.84 副腎:2.67 膵臓:2.91 乳腺:3.73 唾液腺:2.80
CAGE 子宮:0.10 胎盤:0 前立腺:0.21 卵巣:0 精巣:0 心臓:0 骨格筋:0 食道:0.97 胃:- 腸:0.48 結腸:0.04     肝臓:0.55    肺:0.05 膀胱:0.09 腎臓:0.08 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0.36
RNA-seq 子宮:- 胎盤:- 前立腺:0.05 卵巣:0.03 精巣:0.55 心臓:0.02 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0.54        肺:0.08    膀胱:- 腎臓:0.03 下垂体:- 甲状腺:0.07 副腎:3.80 膵臓:- 乳腺:0.14 唾液腺:-

IDs

Refseq ID NM_003701
Gene ID 8600
Unigene ID Hs.333791
Probe set ID 210643_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000120659
GTEx ID ENSG00000120659

オーソログ対応遺伝子

マウス[2]  NM_011613
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9312132
9367155
9396779
9520411
9568710
10224132
10580503
10635328
10708588
11606048
11741951
11751921
11792569
12043011
12221720
12364326
12393586
12393684
12469211
12477932
12564836
12574344
12619938
12682046
12698202
12702561
12756027
12817763
12824189
12923331
12954625
12975380
14699143
14734048
14751235
15044512
15205949
15221493
15248232
15290725
15292354
15304486
15313187
15320903
15322748
15377473
15449141
15476205
15489334
15554353
15564564
15613999
15615493
15615497
15671541
15710592
15722361
15731115
15732858
15794927
15894268
15972386
16052586
16109714
16133687
16143421
16144909
16191370
16215261
16220542
16234249
16240334
16249885
16270354
16317958
16522681
16533764
16572175
16583245
16612568
16681444
16700737
16704959
16730419
16861684
16925460
16953816
16969487
17018528
17042716
17053039
17133360
17151927
17195907
17197168
17241109
17288531
17328065
17328075
17331078
17448630
17506059
17520299
17558893
17560137
17572386
17580719
17593489
17606458
17620507
17632511
17634140
17634142
17667143
17702740
17703334
17852826
17876645
17881498
17891780
17895323
17966895
17970704
17982618
17990294
17993768
18061491
18064531
18072013
18073309
18160010
18172654
18174230
18208894
18253488
18271850
18298349
18301383
18305214
18311801
18319315
18361931
18362509
18367263
18369625
18381203
18389210
18399769
18406448
18435789
18445777
18480302
18502820
18528653
18539107
18556224
18565244
18565252
18586671
18589796
18606301
18606662
18617513
18634923
18645583
18668542
18710934
18727653
18754324
18767923
18802807
18928898
18976975
19008470
19058084
19058836
19073256
19079262
19085839
19105036
19112497
19131500
19134349
19158438
19170075
19185505
19190327
19298221
19299182
19299513
19325145
19352306
19379170
19401376
19415676
19416721
19446344
19449178
19453261
19458885
19473572
19502537
19546479
19548455
19554506
19556344
19633200
19662974
19671684
19699688
19705167
19716455
19781765
19793762
19810098
19847430
19877052
19896533
19913121
19934266
19940926
19967657
20033478
20066901
20084381
20157786
20167120
20205168
20225273
20231205
20237496
20333869
20379614
20412401
20416172
20431232
20506157
20506523
20531232
20533289
20534768
20554715
20628086
20631064
20663885
20690034
20718662
20848544
20861651
20869948
20881963
20890036
20932948
20974615
21074311
21087777
21102463
21124946
21159831
21193069
21259010
21290130
21316442
21326202
21327451
21327765
21328055
21328467
21331661
21352301
21359671
21370405
21371424
21401926
21413932
21474331
21479680
21479768
21514280
21533022
21547906
21561598
21565793
21643971
21649792
21692859
21708014
21725611
21742767
21748518
21777519
21802729
21810381
21814016
21814018
21814019
21814020
21814021
21814022
21814023
21814024
21814025
21814026
21850548
21868322
21880134
21900206
21903860
21941412
21963155
21964949
21970938
21991382
21992185
22001124
22001292
22023082
22025323
22027240
22034880
22049226
22053710
22102368
22116393
22119834
22120987
22172512
22176920
22178057
22185226
22207352
22214279
22242921
22268274
22278426
22278625
22326262
22330139
22402034
22490874
22531921
22546829
22556124
22592030
22627031
22634178
22640692
22664871
22698523
22704876
22705116
22709525
22715006
22753650
22792071
22848465
22867712
22929916
22936827
22952578
22955577
22989723
23018352
23077504
23139212
23176170
23177932
23178378
23183242
23190522
23241893
23244167
23267146
23329761
23336103
23396210
23404437
23437003
23439434
23457386
23499553
23509146
23516466
23531404
23549459
23600327
23612487
23666878
23677868
23697850
23698708
23710436
23744843
23752595
23756197
23762088
23845465
23856613
23869610
23915851
23959668
23971629
23990468
24040204
24048682
24066029
24200492
24249740
24272640
24277958
24296448
24574213

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0045453  bone resorption
GO:0055074  calcium ion homeostasis
GO:0019221  cytokine-mediated signaling pathway
GO:0070371  ERK1 and ERK2 cascade
GO:0006955  immune response
GO:0060749  mammary gland alveolus development
GO:0033598  mammary gland epithelial cell proliferation
GO:0002548  monocyte chemotaxis
GO:0009887  organ morphogenesis
GO:0001503  ossification
GO:0030316  osteoclast differentiation
GO:0045780  positive regulation of bone resorption
GO:0051466  positive regulation of corticotropin-releasing hormone secretion
GO:0034112  positive regulation of homotypic cell-cell adhesion
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046330  positive regulation of JNK cascade
GO:0043406  positive regulation of MAP kinase activity
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045672  positive regulation of osteoclast differentiation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0010740  positive regulation of protein kinase cascade
GO:0050870  positive regulation of T cell activation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051260  protein homooligomerization
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005887  integral to plasma membrane

Molecular Function

GO:0005125  cytokine activity
GO:0005164  tumor necrosis factor receptor binding
GO:0032813  tumor necrosis factor receptor superfamily binding