tumor necrosis factor (ligand) superfamily, member 11

詳細情報を見る

同義遺伝子名

hRANKL2, RANKL, CD254 antigen, sOdf, Osteoprotegerin ligand, Tumor necrosis factor ligand superfamily member 11, TNFSF11, ODF, CD254, OPGL, Osteoclast differentiation factor, TNF-related activation-induced cytokine, TRANCE

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:30.30 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.09 小脳:4.07 脳幹:4.27 脳梁:3.96 松果体:- 末梢神経:3.98 脊柱:4.12 網膜:- 目:- 動脈:4.02 静脈:4.06 リンパ節:4.21 末梢血:- 脾臓:3.90 胸腺:4.04 骨髄:4.28 脂肪:4.25 骨:- 皮膚:4.03
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:1.49 リンパ節:1.63 末梢血:- 脾臓:0.17 胸腺:0.83 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.00 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:26.70 乳腺:- 唾液腺:-
GeneChip 子宮:3.93 胎盤:4.06 前立腺:3.85 卵巣:3.86 精巣:3.92 心臓:4.01 骨格筋:4.12 食道:3.91 胃:3.89 腸:4.09 結腸:4.20 肝臓:3.91 肺:3.77 膀胱:- 腎臓:4.06 下垂体:4.27 甲状腺:3.90 副腎:3.99 膵臓:4.30 乳腺:4.14 唾液腺:4.20
CAGE 子宮:0.10 胎盤:0 前立腺:0.21 卵巣:0 精巣:0 心臓:0 骨格筋:0 食道:0.97 胃:- 腸:0.48 結腸:0.04     肝臓:0.55    肺:0.05 膀胱:0.09 腎臓:0.08 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0.36
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.00 精巣:0.29 心臓:0.00 骨格筋:0 食道:- 胃:- 腸:- 結腸:0     肝臓:0.00        肺:0.00    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.00 副腎:0.10 膵臓:- 乳腺:0.00 唾液腺:-

IDs

Refseq ID NM_033012
Gene ID 8600
Unigene ID Hs.333791
Probe set ID 211153_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000120659
GTEx ID ENSG00000120659

オーソログ対応遺伝子

マウス[2]  NM_011613
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9312132
9367155
9396779
9520411
9568710
10224132
10580503
10635328
10708588
11606048
11741951
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0045453  bone resorption
GO:0055074  calcium ion homeostasis
GO:0019221  cytokine-mediated signaling pathway
GO:0070371  ERK1 and ERK2 cascade
GO:0006955  immune response
GO:0060749  mammary gland alveolus development
GO:0033598  mammary gland epithelial cell proliferation
GO:0002548  monocyte chemotaxis
GO:0009887  organ morphogenesis
GO:0001503  ossification
GO:0030316  osteoclast differentiation
GO:0045780  positive regulation of bone resorption
GO:0051466  positive regulation of corticotropin-releasing hormone secretion
GO:0034112  positive regulation of homotypic cell-cell adhesion
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046330  positive regulation of JNK cascade
GO:0043406  positive regulation of MAP kinase activity
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045672  positive regulation of osteoclast differentiation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0010740  positive regulation of protein kinase cascade
GO:0050870  positive regulation of T cell activation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051260  protein homooligomerization
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005887  integral to plasma membrane

Molecular Function

GO:0005125  cytokine activity
GO:0005164  tumor necrosis factor receptor binding
GO:0032813  tumor necrosis factor receptor superfamily binding