hyaluronoglucosaminidase 2

 詳細情報を見る

同義遺伝子名

hyaluronoglucosaminidase 2, HYAL2, LUCA2, Hyaluronoglucosaminidase-2, LUCA-2, LuCa-2, Hyal-2, Hyaluronidase-2 precursor

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:29.60 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:92 脊柱:- 網膜:- 目:58.80 動脈:- 静脈:- リンパ節:10.10 末梢血:18.20 脾臓:113.40 胸腺:- 骨髄:- 脂肪:161.30 骨:38.40 皮膚:9.60
GeneChip 大脳:6.60 小脳:6.60 脳幹:6.62 脳梁:6.81 松果体:- 末梢神経:6.91 脊柱:6.54 網膜:- 目:- 動脈:7.12 静脈:7.23 リンパ節:7.36 末梢血:- 脾臓:9.08 胸腺:6.07 骨髄:6.77 脂肪:7.70 骨:- 皮膚:7.25
CAGE 大脳:3.51 小脳:- 脳幹:3.31 脳梁:3.39 松果体:3.55 末梢神経:- 脊柱:3.38 網膜:- 目:- 動脈:4.22 静脈:5.12 リンパ節:4.09 末梢血:- 脾臓:6.05 胸腺:1.78 骨髄:- 脂肪:5.27 骨:- 皮膚:-
RNA-seq 大脳:0.41 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.95 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.00 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:54.70 胎盤:145.70 前立腺:56.30 卵巣:74.50 精巣:17.30 心臓:89.40 骨格筋:60.30 食道:- 胃:- 腸:- 結腸:17     肝臓:10.60        肺:97.80    膀胱:- 腎臓:52 下垂体:116 甲状腺:- 副腎:203.10 膵臓:53.30 乳腺:9.30 唾液腺:-
GeneChip 子宮:7.32 胎盤:7.44 前立腺:6.78 卵巣:7.26 精巣:6.88 心臓:7.60 骨格筋:6.81 食道:7.17 胃:7.26 腸:7.38 結腸:7.37 肝臓:7.21 肺:8.87 膀胱:- 腎臓:7.38 下垂体:6.96 甲状腺:7.48 副腎:7.69 膵臓:7.19 乳腺:7.34 唾液腺:6.73
CAGE 子宮:4.33 胎盤:4.63 前立腺:3.82 卵巣:4.09 精巣:3.79 心臓:4.85 骨格筋:3.85 食道:3.93 胃:- 腸:3.59 結腸:3.60     肝臓:4.24    肺:5.58 膀胱:3.70 腎臓:4.94 下垂体:3.82 甲状腺:4.49 副腎:- 膵臓:3.47 乳腺:5.42 唾液腺:3.32
RNA-seq 子宮:- 胎盤:- 前立腺:0.98 卵巣:0.47 精巣:0.56 心臓:0.81 骨格筋:0.51 食道:- 胃:- 腸:- 結腸:0.88     肝臓:1.38        肺:2.34    膀胱:- 腎臓:1.46 下垂体:- 甲状腺:1.23 副腎:1.54 膵臓:- 乳腺:0.41 唾液腺:-

詳細情報

IDs

Refseq ID NM_033158
Gene ID 8692
Unigene ID Hs.76873
Probe set ID 206855_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000068001
GTEx ID ENSG00000068001

オーソログ対応遺伝子

マウス[2]  NM_010489
ラット[2]  NM_172040

染色体

3p21.31  [50,355,221  -  50,360,337]

遺伝子ファミリー (Interpro ID)

IPR018155  Hyaluronidase

Link to Pubmed  (Pubmed ID)

8125298
8603390
8619474
9110174
9712871
9790770
9933825
10989127
11085536
11296287
11731268
11944887
12174938
12477932
12584308
12676986
12684632
14702039
15489334
15596803
15923194
16191204
16344560
16600643
16641997
16837837
16990026
17170110
17229709
18390475
18725949
19081476
19140316
19366691
19435493
19443707
19577615
20072653
20554532
20849597
20864512
20875124
21743962
23560496

遺伝子オントロジー  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0051216  cartilage development
GO:0071347  cellular response to interleukin-1
GO:0071356  cellular response to tumor necrosis factor
GO:0071493  cellular response to UV-B
GO:0051607  defense response to virus
GO:0046718  entry of virus into host cell
GO:0006027  glycosaminoglycan catabolic process
GO:0030203  glycosaminoglycan metabolic process
GO:0002244  hemopoietic progenitor cell differentiation
GO:0030214  hyaluronan catabolic process
GO:0030212  hyaluronan metabolic process
GO:0001822  kidney development
GO:0042117  monocyte activation
GO:0010259  multicellular organismal aging
GO:0060586  multicellular organismal iron ion homeostasis
GO:0030308  negative regulation of cell growth
GO:0010764  negative regulation of fibroblast migration
GO:0043407  negative regulation of MAP kinase activity
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0043065  positive regulation of apoptosis
GO:0050729  positive regulation of inflammatory response
GO:0042307  positive regulation of protein import into nucleus
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0070295  renal water absorption
GO:0046677  response to antibiotic
GO:0000302  response to reactive oxygen species
GO:0009615  response to virus
GO:0048705  skeletal system morphogenesis
GO:0019087  transformation of host cell by virus
GO:0019064  viral envelope fusion with host membrane

Cellular Component

GO:0031362  anchored to external side of plasma membrane
GO:0046658  anchored to plasma membrane
GO:0016324  apical plasma membrane
GO:0009986  cell surface
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0044444  cytoplasmic part
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0030139  endocytic vesicle
GO:0005783  endoplasmic reticulum
GO:0000139  Golgi membrane
GO:0005764  lysosome
GO:0045121  membrane raft
GO:0005902  microvillus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0019899  enzyme binding
GO:0005540  hyaluronic acid binding
GO:0033906  hyaluronoglucuronidase activity
GO:0004415  hyalurononglucosaminidase activity
GO:0005515  protein binding
GO:0030294  receptor signaling protein tyrosine kinase inhibitor activity
GO:0030971  receptor tyrosine kinase binding
GO:0050431  transforming growth factor beta binding
GO:0001618  viral receptor activity