receptor-interacting serine-threonine kinase 2

同義遺伝子名

RIP2, GIG30, Receptor-interacting protein 2, receptor-interacting serine-threonine kinase 2, RIP-like-interacting CLARP kinase, CCK, CARD-containing IL-1 beta ICE-kinase, RICK, RIP-2, CARDIAK, RIPK2, UNQ277/PRO314/PRO34092, CARD3

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:27.30

小脳:-

脳幹:-

脳梁:29.20

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:11.80

動脈:179.90

静脈:-

リンパ節:50.60

末梢血:-

脾臓:37.80

胸腺:25.80

骨髄:-

脂肪:-

骨:12.80

皮膚:9.60

GeneChip

大脳:6.46

小脳:6.30

脳幹:6.55

脳梁:6.81

松果体:-

末梢神経:6.83

脊柱:7.19

網膜:-

目:-

動脈:6.83

静脈:7.30

リンパ節:6.79

末梢血:-

脾臓:6.89

胸腺:6.42

骨髄:6.83

脂肪:6.99

骨:-

皮膚:7.14

CAGE

大脳:2.64

小脳:-

脳幹:2.90

脳梁:3.04

松果体:2.21

末梢神経:-

脊柱:3.35

網膜:-

目:-

動脈:2.97

静脈:2.89

リンパ節:3.01

末梢血:-

脾臓:3.27

胸腺:2.25

骨髄:-

脂肪:3.18

骨:-

皮膚:-

RNA-seq

大脳:2.54

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.83

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.75

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:27.30

胎盤:69.20

前立腺:33.80

卵巣:37.30

精巣:21.60

心臓:25.50

骨格筋:-

食道:-

胃:169.90

腸:32.40

結腸:25.40

肝臓:-

肺:44

膀胱:125.60

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:8.90

乳腺:55.80

唾液腺:-

GeneChip

子宮:6.94

胎盤:7.78

前立腺:7.24

卵巣:6.73

精巣:6.66

心臓:6.88

骨格筋:6.09

食道:6.69

胃:6.83

腸:6.82

結腸:6.76

肝臓:6.67

肺:7.30

膀胱:-

腎臓:6.47

下垂体:6.59

甲状腺:6.56

副腎:6.30

膵臓:7.23

乳腺:6.83

唾液腺:6.82

CAGE

子宮:2.92

胎盤:3.55

前立腺:2.87

卵巣:2.85

精巣:2.37

心臓:2.95

骨格筋:1.67

食道:2.82

胃:-

腸:2.46

結腸:2.63

肝臓:2.78

肺:3.31

膀胱:3.33

腎臓:2.73

下垂体:2.68

甲状腺:2.76

副腎:-

膵臓:2.48

乳腺:2.99

唾液腺:2.80

RNA-seq

子宮:-

胎盤:-

前立腺:2.75

卵巣:2.75

精巣:2.67

心臓:2.07

骨格筋:0.98

食道:-

胃:-

腸:-

結腸:2.74

肝臓:1.63

肺:3.97

膀胱:-

腎臓:2.24

下垂体:-

甲状腺:2.32

副腎:2.68

膵臓:-

乳腺:2.55

唾液腺:-

IDs

Refseq ID	NM_003821
Gene ID	8767
Unigene ID	Hs.103755
Probe set ID	209545_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000104312
GTEx ID	ENSG00000104312

オーソログ対応遺伝子

マウス[2]	NM_138952
ラット [0]

染色体

8q21.3 [90,769,975 - 90,803,291]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001315	Caspase Recruitment
IPR011029	DEATH-like
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0002250	adaptive immune response
GO:0006915	apoptosis
GO:0071223	cellular response to lipoteichoic acid
GO:0071224	cellular response to peptidoglycan
GO:0050830	defense response to Gram-positive bacterium
GO:0007249	I-kappaB kinase/NF-kappaB cascade
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0007254	JNK cascade
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0048011	nerve growth factor receptor signaling pathway
GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0046641	positive regulation of alpha-beta T cell proliferation
GO:0043065	positive regulation of apoptosis
GO:0032722	positive regulation of chemokine production
GO:0001961	positive regulation of cytokine-mediated signaling pathway
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0033091	positive regulation of immature T cell proliferation
GO:0032727	positive regulation of interferon-alpha production
GO:0032728	positive regulation of interferon-beta production
GO:0032729	positive regulation of interferon-gamma production
GO:0032735	positive regulation of interleukin-12 production
GO:0032743	positive regulation of interleukin-2 production
GO:0032755	positive regulation of interleukin-6 production
GO:0046330	positive regulation of JNK cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0031398	positive regulation of protein ubiquitination
GO:0045627	positive regulation of T-helper 1 cell differentiation
GO:0002827	positive regulation of T-helper 1 type immune response
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032760	positive regulation of tumor necrosis factor production
GO:0043330	response to exogenous dsRNA
GO:0070555	response to interleukin-1
GO:0070671	response to interleukin-12
GO:0070673	response to interleukin-18
GO:0007165	signal transduction
GO:0051403	stress-activated MAPK cascade
GO:0042098	T cell proliferation
GO:0050852	T cell receptor signaling pathway
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol

Molecular Function

GO:0005524	ATP binding
GO:0050700	CARD domain binding
GO:0030274	LIM domain binding
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004674	protein serine/threonine kinase activity
GO:0004871	signal transducer activity

receptor-interacting serine-threonine kinase 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function