histone deacetylase 3

詳細情報を見る

同義遺伝子名

histone deacetylase 3, HD3, SMAP45, RPD3-2, Histone deacetylase 3, HDAC3

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:26.10 小脳:25.20 脳幹:- 脳梁:- 松果体:- 末梢神経:61.30 脊柱:112.30 網膜:- 目:76.40 動脈:- 静脈:- リンパ節:111.20 末梢血:91.10 脾臓:18.90 胸腺:12.90 骨髄:59 脂肪:40.30 骨:- 皮膚:86.40
GeneChip 大脳:6.69 小脳:6.93 脳幹:6.67 脳梁:6.60 松果体:- 末梢神経:7.02 脊柱:6.71 網膜:- 目:- 動脈:7.24 静脈:6.97 リンパ節:7.48 末梢血:- 脾臓:7.41 胸腺:7.33 骨髄:7.47 脂肪:7.21 骨:- 皮膚:7.62
CAGE 大脳:2.10 小脳:- 脳幹:2.12 脳梁:2.02 松果体:1.75 末梢神経:- 脊柱:2.06 網膜:- 目:- 動脈:2.85 静脈:2.42 リンパ節:2.76 末梢血:- 脾臓:2.01 胸腺:2.29 骨髄:- 脂肪:2.03 骨:- 皮膚:-
RNA-seq 大脳:3.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.14 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.74 骨:- 皮膚:-
EST 子宮:54.70 胎盤:65.60 前立腺:56.30 卵巣:186.30 精巣:56.20 心臓:51.10 骨格筋:40.20 食道:- 胃:148.70 腸:- 結腸:93.30     肝臓:52.80        肺:78.20    膀胱:- 腎臓:72.80 下垂体:- 甲状腺:- 副腎:- 膵臓:88.90 乳腺:55.80 唾液腺:-
GeneChip 子宮:7.30 胎盤:7.26 前立腺:7.37 卵巣:7.32 精巣:7.08 心臓:6.97 骨格筋:7.15 食道:7.46 胃:7.23 腸:7.11 結腸:7.18 肝臓:7.34 肺:7.13 膀胱:- 腎臓:7.36 下垂体:7.29 甲状腺:7.48 副腎:7.50 膵臓:7.16 乳腺:7.57 唾液腺:7.19
CAGE 子宮:1.94 胎盤:2.27 前立腺:2.15 卵巣:2.19 精巣:2.27 心臓:2.40 骨格筋:1.92 食道:2.24 胃:- 腸:1.87 結腸:2.49     肝臓:2.24    肺:2.51 膀胱:2.08 腎臓:1.94 下垂体:1.94 甲状腺:2.17 副腎:- 膵臓:2.71 乳腺:2.69 唾液腺:2.17
RNA-seq 子宮:- 胎盤:- 前立腺:4.29 卵巣:4.26 精巣:4.01 心臓:3.54 骨格筋:3.86 食道:- 胃:- 腸:- 結腸:2.90     肝臓:3.64        肺:3.52    膀胱:- 腎臓:3.95 下垂体:- 甲状腺:4.28 副腎:4.15 膵臓:- 乳腺:3.83 唾液腺:-

IDs

Refseq ID NM_003883
Gene ID 8841
Unigene ID Hs.519632
Probe set ID 216326_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171720
GTEx ID ENSG00000171720

オーソログ対応遺伝子

マウス[1]  NM_010411
ラット[1]  NM_053448

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9346952
9360932
9464271
9501169
9722949
10051405
10220385
10490602
10575214
10581039
10655483
10669754
10777477
10809664
10860984
10869435
10898795
10944117
10958676
10983972
11006275
11013263
11022042
11046157
11259576
11302704
11439334
11463856
11466315
11470869
11486036
11509652
11533236
11533489
11567998
11641274
11641275
11777905
11779848
11788710
11804585
11861901
11867539
11867749
11889044
11923873
11931768
12015313
12032081
12048199
12150997
12205093
12239342
12242670
12371150
12393887
12403844
12419806
12477932
12479814
12502735
12535528
12590135
12628926
12711221
12853483
12861000
12943985
12972430
14521922
14525983
14527417
14668799
14684825
14722073
15016912
15051733
15140878
15184363
15192014
15292260
15297880
15333839
15356147
15467736
15469820
15489334
15494311
15558026
15561719
15572445
15601853
15619633
15653507
15711539
15713663
15761026
15805470
15831498
15831516
15832170
15835920
15837933
15917248
15927959
16022908
16033423
16055724
16129885
16186112
16195251
16204234
16227606
16249187
16288017
16298343
16371367
16432238
16469706
16481466
16481475
16528103
16532030
16569215
16652147
16712523
16730330
16820529
16847267
16849648
16865259
16917504
16919237
16924111
16943425
16980585
16987993
17007107
17008592
17015477
17053781
17075044
17079677
17101790
17126328
17141982
17158926
17172643
17182846
17227585
17242407
17245431
17255935
17273746
17311813
17353931
17620012
17621263
17675290
17699109
17786334
17849419
17873065
17895379
17908689
17910034
17925399
17956871
17970752
18037959
18097041
18202150
18212746
18241676
18245468
18321663
18326024
18347167
18377363
18403372
18417529
18439917
18483244
18523274
18542060
18558095
18585351
18619497
18655026
18667423
18769117
18789002
18832068
18854353
18940814
18948102
19015268
19032343
19081374
19099586
19121623
19204783
19244234
19279113
19341714
19453261
19463978
19583777
19738286
19855430
19912635
19956841
19995069
20026773
20049841
20200160
20211142
20385135
20415600
20471694
20473547
20484017
20534529
20547759
20563766
20691163
20705923
20731616
21030595
21059642
21081493
21081666
21139048
21143702
21179472
21206745
21258344
21262769
21324898
21346816
21444723
21453528
21527249
21532573
21549311
21624135
21637537
21670149
21685935
21868449
21884981
21972094
22002311
22027828
22116549
22190034
22190037
22230954
22294699
22337871
22349439
22363205
22455388
22508987
22641068
22647876
22649097
22651256
22685561
22730529
22763818
22796363
22797925
22939629
22989952
23079660
23395002
23402757
23615070
23667531
23685192
23752268
23760262
23857786
23879963
23904210
24045946
24120624
24250222
24324066
24419085
24449765
24482232
24654937
24821727

遺伝子オントロジー  (GO ID)

Biological Process

GO:0044255  cellular lipid metabolic process
GO:0016568  chromatin modification
GO:0032922  circadian regulation of gene expression
GO:0043066  negative regulation of apoptosis
GO:0045786  negative regulation of cell cycle
GO:0046329  negative regulation of JNK cascade
GO:0010832  negative regulation of myotube differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007219  Notch signaling pathway
GO:0006476  protein amino acid deacetylation
GO:0007346  regulation of mitotic cell cycle
GO:0040014  regulation of multicellular organism growth
GO:0051225  spindle assembly
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000118  histone deacetylase complex
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005876  spindle microtubule
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0031490  chromatin DNA binding
GO:0019899  enzyme binding
GO:0004407  histone deacetylase activity
GO:0042826  histone deacetylase binding
GO:0032041  NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969  NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970  NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0005515  protein binding
GO:0033558  protein deacetylase activity
GO:0003714  transcription corepressor activity
GO:0008134  transcription factor binding