activin A receptor, type I



Activin receptor-like kinase 2, Activin receptor type I, ALK2, activin A receptor, type I, TSR-I, TGF-B superfamily receptor type I, Activin receptor type-1 precursor, SKR1, ACTRI, Serine/threonine-protein kinase receptor R1, ACTR-I, ACVRLK2, ACVR1, ALK-2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。


EST 大脳:32 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:61.30 脊柱:- 網膜:- 目:58.80 動脈:179.90 静脈:- リンパ節:10.10 末梢血:18.20 脾臓:18.90 胸腺:- 骨髄:19.70 脂肪:- 骨:25.60 皮膚:33.60
GeneChip nodata
CAGE 大脳:3.15 小脳:- 脳幹:3.08 脳梁:2.83 松果体:4.43 末梢神経:- 脊柱:3.35 網膜:- 目:- 動脈:4.01 静脈:3.27 リンパ節:3.10 末梢血:- 脾臓:2.93 胸腺:2.66 骨髄:- 脂肪:3.45 骨:- 皮膚:-
RNA-seq nodata
EST 子宮:82 胎盤:18.20 前立腺:- 卵巣:37.30 精巣:4.30 心臓:114.90 骨格筋:20.10 食道:- 胃:63.70 腸:- 結腸:33.90     肝臓:21.10        肺:34.20    膀胱:- 腎臓:104 下垂体:- 甲状腺:- 副腎:- 膵臓:97.80 乳腺:55.80 唾液腺:-
GeneChip nodata
CAGE 子宮:3.63 胎盤:3.22 前立腺:3.62 卵巣:3.51 精巣:2.90 心臓:3.80 骨格筋:2.35 食道:3.19 胃:- 腸:3.17 結腸:3.34     肝臓:3.25    肺:3.72 膀胱:3.54 腎臓:3.44 下垂体:3.19 甲状腺:3.82 副腎:- 膵臓:2.90 乳腺:4.59 唾液腺:2.69
RNA-seq nodata

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032924  activin receptor signaling pathway
GO:0002526  acute inflammatory response
GO:0003289  atrial septum primum morphogenesis
GO:0030509  BMP signaling pathway
GO:0060923  cardiac muscle cell fate commitment
GO:0071385  cellular response to glucocorticoid stimulus
GO:0007368  determination of left/right symmetry
GO:0003143  embryonic heart tube morphogenesis
GO:0000082  G1/S transition of mitotic cell cycle
GO:0001702  gastrulation with mouth forming second
GO:0007281  germ cell development
GO:0001701  in utero embryonic development
GO:0001707  mesoderm formation
GO:0003183  mitral valve morphogenesis
GO:0032926  negative regulation of activin receptor signaling pathway
GO:0009968  negative regulation of signal transduction
GO:0001755  neural crest cell migration
GO:0060389  pathway-restricted SMAD protein phosphorylation
GO:0001569  patterning of blood vessels
GO:0018107  peptidyl-threonine phosphorylation
GO:0060037  pharyngeal system development
GO:0030501  positive regulation of bone mineralization
GO:0045669  positive regulation of osteoblast differentiation
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006468  protein amino acid phosphorylation
GO:0030278  regulation of ossification
GO:0048641  regulation of skeletal muscle tissue development
GO:0051145  smooth muscle cell differentiation
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001655  urogenital system development

Cellular Component

GO:0048179  activin receptor complex
GO:0045177  apical part of cell
GO:0005887  integral to plasma membrane

Molecular Function

GO:0048185  activin binding
GO:0016361  activin receptor activity, type I
GO:0005524  ATP binding
GO:0046872  metal ion binding
GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0004702  receptor signaling protein serine/threonine kinase activity
GO:0046332  SMAD binding
GO:0050431  transforming growth factor beta binding
GO:0005025  transforming growth factor beta receptor activity, type I
GO:0004675  transmembrane receptor protein serine/threonine kinase activity