activin A receptor, type IB



ALK-4, ACVRLK4, ACVR1B, Activin receptor type 1B precursor, Activin receptor-like kinase 4, ALK4, activin A receptor, type IB, Serine/threonine-protein kinase receptor R2, SKR2, ACTR-IB, ACTRIB

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。


EST 大脳:83 小脳:37.80 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:52.90 動脈:- 静脈:- リンパ節:10.10 末梢血:18.20 脾臓:18.90 胸腺:25.80 骨髄:59 脂肪:- 骨:- 皮膚:76.80
GeneChip 大脳:3.84 小脳:3.69 脳幹:3.83 脳梁:3.72 松果体:- 末梢神経:3.87 脊柱:3.93 網膜:- 目:- 動脈:3.98 静脈:4.08 リンパ節:3.77 末梢血:- 脾臓:3.74 胸腺:3.62 骨髄:4.17 脂肪:3.96 骨:- 皮膚:4.15
CAGE 大脳:2.90 小脳:- 脳幹:2.24 脳梁:2.14 松果体:2.90 末梢神経:- 脊柱:2.21 網膜:- 目:- 動脈:2.95 静脈:2.11 リンパ節:2.55 末梢血:- 脾臓:2.23 胸腺:1.75 骨髄:- 脂肪:2.61 骨:- 皮膚:-
RNA-seq 大脳:1.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.90 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.29 骨:- 皮膚:-
EST 子宮:9.10 胎盤:18.20 前立腺:56.30 卵巣:37.30 精巣:47.60 心臓:25.50 骨格筋:20.10 食道:- 胃:85 腸:- 結腸:93.30     肝臓:10.60        肺:29.30    膀胱:- 腎臓:135.20 下垂体:- 甲状腺:- 副腎:- 膵臓:53.30 乳腺:195.20 唾液腺:-
GeneChip 子宮:3.69 胎盤:3.69 前立腺:3.82 卵巣:3.67 精巣:3.82 心臓:3.78 骨格筋:4.10 食道:4.01 胃:3.88 腸:4.01 結腸:4.15 肝臓:3.76 肺:3.89 膀胱:- 腎臓:4.02 下垂体:3.70 甲状腺:3.60 副腎:3.75 膵臓:4.38 乳腺:3.53 唾液腺:3.83
CAGE 子宮:2.34 胎盤:1.39 前立腺:2.66 卵巣:2.43 精巣:2.73 心臓:2.43 骨格筋:2.64 食道:2.79 胃:- 腸:3.33 結腸:3.37     肝臓:3.18    肺:2.61 膀胱:2.55 腎臓:3.43 下垂体:2.87 甲状腺:2.65 副腎:- 膵臓:3.78 乳腺:3.02 唾液腺:3.45
RNA-seq 子宮:- 胎盤:- 前立腺:0.64 卵巣:2.04 精巣:2.27 心臓:0.32 骨格筋:0.61 食道:- 胃:- 腸:- 結腸:1.47     肝臓:1.40        肺:2.38    膀胱:- 腎臓:1.79 下垂体:- 甲状腺:1.66 副腎:1.89 膵臓:- 乳腺:2.29 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032924  activin receptor signaling pathway
GO:0007417  central nervous system development
GO:0046545  development of primary female sexual characteristics
GO:0000082  G1/S transition of mitotic cell cycle
GO:0001942  hair follicle development
GO:0001701  in utero embryonic development
GO:0030308  negative regulation of cell growth
GO:0018107  peptidyl-threonine phosphorylation
GO:0032927  positive regulation of activin receptor signaling pathway
GO:0045648  positive regulation of erythrocyte differentiation
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0007165  signal transduction
GO:0007178  transmembrane receptor protein serine/threonine kinase signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0048185  activin binding
GO:0017002  activin receptor activity
GO:0016361  activin receptor activity, type I
GO:0005524  ATP binding
GO:0019838  growth factor binding
GO:0034711  inhibin binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0004674  protein serine/threonine kinase activity
GO:0004702  receptor signaling protein serine/threonine kinase activity
GO:0046332  SMAD binding
GO:0005024  transforming growth factor beta receptor activity
GO:0004675  transmembrane receptor protein serine/threonine kinase activity
GO:0031625  ubiquitin protein ligase binding