ribosomal protein S6 kinase, 90kDa, polypeptide 5

同義遺伝子名

Ribosomal protein S6 kinase alpha-5, RSKL, RSK-like protein kinase, RLPK, MGC1911, MSK1, MSPK1, ribosomal protein S6 kinase, 90kDa, polypeptide 5, RPS6KA5, 90 kDa ribosomal protein S6 kinase 5

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:46.20

小脳:37.80

脳幹:-

脳梁:-

松果体:-

末梢神経:61.30

脊柱:-

網膜:118.60

目:23.50

動脈:30

静脈:-

リンパ節:80.90

末梢血:18.20

脾臓:-

胸腺:38.70

骨髄:118.10

脂肪:-

骨:12.80

皮膚:28.80

GeneChip

nodata

CAGE

大脳:3.38

小脳:-

脳幹:3.33

脳梁:3.42

松果体:2.63

末梢神経:-

脊柱:3.49

網膜:-

目:-

動脈:2.50

静脈:2.46

リンパ節:2.63

末梢血:-

脾臓:2.20

胸腺:2.44

骨髄:-

脂肪:1.86

骨:-

皮膚:-

RNA-seq

大脳:0.44

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.14

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:0.07

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:54.60

前立腺:22.50

卵巣:-

精巣:4.30

心臓:-

骨格筋:-

食道:-

胃:85

腸:32.40

結腸:42.40

肝臓:-

肺:24.40

膀胱:-

腎臓:20.80

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:37.20

唾液腺:-

GeneChip

nodata

CAGE

子宮:3.09

胎盤:3.53

前立腺:3.03

卵巣:2.27

精巣:2.17

心臓:2.23

骨格筋:2.81

食道:3.02

胃:-

腸:3.15

結腸:3.18

肝臓:1.41

肺:2.51

膀胱:3.18

腎臓:1.55

下垂体:2.71

甲状腺:1.85

副腎:-

膵臓:2.48

乳腺:2.53

唾液腺:2.78

RNA-seq

子宮:-

胎盤:-

前立腺:0.05

卵巣:0.00

精巣:0.29

心臓:0.00

骨格筋:0.25

食道:-

胃:-

腸:-

結腸:0.00

肝臓:0.00

肺:0.04

膀胱:-

腎臓:0.09

下垂体:-

甲状腺:0.05

副腎:0.00

膵臓:-

乳腺:0.00

唾液腺:-

IDs

Refseq ID	NM_182398
Gene ID	9252
Unigene ID	Hs.510225
Probe set ID	-
Ensembl ID	ENSG00000100784
GTEx ID	ENSG00000100784

オーソログ対応遺伝子

マウス[2]	NM_153587
ラット[1]	NM_001108048

染色体

14q32.11 [91,336,799 - 91,526,980]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0007411	axon guidance
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0043990	histone H2A-S1 phosphorylation
GO:0043987	histone H3-S10 phosphorylation
GO:0043988	histone H3-S28 phosphorylation
GO:0016572	histone phosphorylation
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0070498	interleukin-1-mediated signaling pathway
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0001818	negative regulation of cytokine production
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048011	nerve growth factor receptor signaling pathway
GO:0032793	positive regulation of CREB transcription factor activity
GO:0035066	positive regulation of histone acetylation
GO:0033129	positive regulation of histone phosphorylation
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006468	protein amino acid phosphorylation
GO:0007243	protein kinase cascade
GO:0006355	regulation of transcription, DNA-dependent
GO:0009605	response to external stimulus
GO:0006950	response to stress
GO:0051403	stress-activated MAPK cascade
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0005524	ATP binding
GO:0000287	magnesium ion binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity