aldo-keto reductase family 1, member C18

 詳細情報を見る

同義遺伝子名

aldo-keto reductase family 1, member C18, Aldo-keto reductase family 1 member C18, 20alpha-HSD, 20-alpha-HSD, Akr1c18, 20-alpha-hydroxysteroid dehydrogenase, AW146047

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:28.80 脾臓:381.80 胸腺:19.80 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:5.81 小脳:5.65 脳幹:- 脳梁:- 松果体:- 末梢神経:5.21 脊柱:5.40 網膜:5.26 目:5.84 動脈:- 静脈:5.55 リンパ節:5.25 末梢血:- 脾臓:5.23 胸腺:- 骨髄:5.44 脂肪:5.99 骨:5.32 皮膚:5.54
CAGE 大脳:0.41 小脳:- 脳幹:0.09 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.14 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0.67 骨髄:- 脂肪:- 骨:0 皮膚:2.45
RNA-seq 大脳:3.41 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:43.60 胎盤:13.80 前立腺:- 卵巣:- 精巣:- 心臓:37.20 骨格筋:- 食道:- 胃:- 腸:73.90 結腸:17.60     肝臓:-        肺:-    膀胱:- 腎臓:56.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:13.10 唾液腺:-
GeneChip 子宮:6.40 胎盤:6.44 前立腺:5.55 卵巣:8.87 精巣:5.48 心臓:5.90 骨格筋:5.57 食道:- 胃:5.43 腸:5.55 結腸:- 肝臓:6.27 肺:5.14 膀胱:5.09 腎臓:8.51 下垂体:5.11 甲状腺:- 副腎:5.04 膵臓:5.57 乳腺:6.24 唾液腺:5.55
CAGE 子宮:0.55 胎盤:2.88 前立腺:0 卵巣:5.10 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.58 結腸:0     肝臓:0.47    肺:0.91 膀胱:0.33 腎臓:- 下垂体:0 甲状腺:- 副腎:0.14 膵臓:0 乳腺:1.32 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:100.93        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_134066
Gene ID 105349
Unigene ID Mm.41337
Probe set ID 1419136_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021214

オーソログ対応遺伝子

ヒト [0]  
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR001395  Aldo/keto reductase
IPR020471  Aldo/keto reductase subgroup

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
12466851
12477932
12562828
14610273
14681479
14967952
15193432
15222881
15471942
15489334
15860270
16141072
16141073
17122075
17255200
17272929
17629694
17872381
18667791
19273550
19955443
21267068
21820362
22529366
23471215
23685333

遺伝子オントロジー  (GO ID)

Biological Process

GO:0071276  cellular response to cadmium ion
GO:0071277  cellular response to calcium ion
GO:0071384  cellular response to corticosteroid stimulus
GO:0071395  cellular response to jasmonic acid stimulus
GO:0071379  cellular response to prostaglandin stimulus
GO:0034614  cellular response to reactive oxygen species
GO:0016488  farnesol catabolic process
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0055114  oxidation reduction
GO:0007567  parturition
GO:0010942  positive regulation of cell death
GO:0008284  positive regulation of cell proliferation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0006709  progesterone catabolic process
GO:0042448  progesterone metabolic process
GO:0000060  protein import into nucleus, translocation
GO:0048385  regulation of retinoic acid receptor signaling pathway
GO:0050810  regulation of steroid biosynthetic process
GO:0034694  response to prostaglandin stimulus
GO:0042574  retinal metabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005622  intracellular
GO:0005634  nucleus

Molecular Function

GO:0047020  15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
GO:0047006  20-alpha-hydroxysteroid dehydrogenase activity
GO:0047023  3(or 17)-alpha-hydroxysteroid dehydrogenase activity
GO:0004032  aldehyde reductase activity
GO:0047787  delta4-3-oxosteroid 5beta-reductase activity
GO:0045550  geranylgeranyl reductase activity
GO:0045703  ketoreductase activity
GO:0047086  ketosteroid monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016655  oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
GO:0018636  phenanthrene 9,10-monooxygenase activity
GO:0004958  prostaglandin F receptor activity
GO:0001758  retinal dehydrogenase activity
GO:0004745  retinol dehydrogenase activity