cholinergic receptor, nicotinic, alpha polypeptide 7

詳細情報を見る

同義遺伝子名

alpha7 nicotinic receptor, alpha7, Acra7, Chrna7

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:19.10

小脳:-

脳幹:31.80

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:5

小脳:4.83

脳幹:-

脳梁:-

松果体:-

末梢神経:5.47

脊柱:4.97

網膜:4.58

目:4.82

動脈:-

静脈:4.57

リンパ節:4.57

末梢血:-

脾臓:4.55

胸腺:-

骨髄:4.58

脂肪:4.74

骨:4.69

皮膚:4.92

CAGE

大脳:2.17

小脳:-

脳幹:2.46

脳梁:-

松果体:-

末梢神経:-

脊柱:2.40

網膜:-

目:-

動脈:0.14

静脈:-

リンパ節:0

末梢血:-

脾臓:0

胸腺:0

骨髄:-

脂肪:-

骨:0

皮膚:0.15

RNA-seq

大脳:1.13

小脳:1.13

脳幹:1.13

脳梁:1.13

松果体:1.13

末梢神経:1.13

脊柱:1.13

網膜:1.13

目:1.13

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:30.90

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.53

胎盤:4.72

前立腺:4.77

卵巣:4.53

精巣:4.99

心臓:4.95

骨格筋:5.10

食道:-

胃:4.86

腸:4.80

結腸:-

肝臓:4.74

肺:4.68

膀胱:4.86

腎臓:4.69

下垂体:4.60

甲状腺:-

副腎:4.75

膵臓:4.76

乳腺:4.71

唾液腺:4.96

CAGE

子宮:0.90

胎盤:0.18

前立腺:1.09

卵巣:0.45

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:0

腸:0

結腸:0

肝臓:0

肺:0.83

膀胱:0.57

腎臓:-

下垂体:1.40

甲状腺:-

副腎:2.93

膵臓:0

乳腺:0

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007390
Gene ID	11441
Unigene ID	Mm.113464
Probe set ID	1450299_at [Mouse430_2]
Ensembl ID	ENSMUSG00000030525

オーソログ対応遺伝子

ヒト[1]	NM_000746, NM_001190455
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR006201

Neurotransmitter-gated ion-channel

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0008306	associative learning
GO:0042113	B cell activation
GO:0048149	behavioral response to ethanol
GO:0035095	behavioral response to nicotine
GO:0006816	calcium ion transport
GO:0006812	cation transport
GO:0006874	cellular calcium ion homeostasis
GO:0050890	cognition
GO:0006897	endocytosis
GO:0060112	generation of ovulation cycle rhythm
GO:0034220	ion transmembrane transport
GO:0006811	ion transport
GO:0007613	memory
GO:0050728	negative regulation of inflammatory response
GO:0032691	negative regulation of interleukin-1 beta production
GO:0032715	negative regulation of interleukin-6 production
GO:0032720	negative regulation of tumor necrosis factor production
GO:0042698	ovulation cycle
GO:0045766	positive regulation of angiogenesis
GO:0008284	positive regulation of cell proliferation
GO:0001988	positive regulation of heart rate in baroreceptor response to decreased systemic arterial blood pressure
GO:0019228	regulation of action potential in neuron
GO:0050727	regulation of inflammatory response
GO:0042391	regulation of membrane potential
GO:0014061	regulation of norepinephrine secretion
GO:0032225	regulation of synaptic transmission, dopaminergic
GO:0045471	response to ethanol
GO:0032094	response to food
GO:0001666	response to hypoxia
GO:0035094	response to nicotine
GO:0007165	signal transduction
GO:0030317	sperm motility
GO:0007271	synaptic transmission, cholinergic
GO:0042110	T cell activation
GO:0006810	transport

Cellular Component

GO:0016324	apical plasma membrane
GO:0032279	asymmetric synapse
GO:0030424	axon
GO:0030054	cell junction
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043198	dendritic shaft
GO:0043197	dendritic spine
GO:0009897	external side of plasma membrane
GO:0030426	growth cone
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0042734	presynaptic membrane
GO:0045202	synapse

Molecular Function

GO:0042166	acetylcholine binding
GO:0015464	acetylcholine receptor activity
GO:0008179	adenylate cyclase binding
GO:0051117	ATPase binding
GO:0001540	beta-amyloid binding
GO:0017081	chloride channel regulator activity
GO:0008144	drug binding
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005216	ion channel activity
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0015643	toxin binding

cholinergic receptor, nicotinic, alpha polypeptide 7

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function