a disintegrin and metallopeptidase domain 17

詳細情報を見る

同義遺伝子名

A disintegrin and metalloproteinase domain 17, a disintegrin and metallopeptidase domain 17, CD156b, TNF-alpha convertase, ADAM 17 precursor, Adam17, TNF-alpha-converting enzyme, Tace, CD156b antigen

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:102.50 小脳:18.40 脳幹:63.60 脳梁:- 松果体:257.80 末梢神経:- 脊柱:141.90 網膜:- 目:159.60 動脈:168.80 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:49.40 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:6.71 小脳:7.03 脳幹:- 脳梁:- 松果体:- 末梢神経:7.04 脊柱:7.24 網膜:7.28 目:7.83 動脈:- 静脈:8.41 リンパ節:9.12 末梢血:- 脾臓:8.83 胸腺:- 骨髄:8.29 脂肪:7.89 骨:8.19 皮膚:8.88
CAGE 大脳:2.54 小脳:- 脳幹:2.54 脳梁:- 松果体:- 末梢神経:- 脊柱:2.76 網膜:- 目:- 動脈:3.34 静脈:- リンパ節:4.65 末梢血:- 脾臓:3.52 胸腺:3.59 骨髄:- 脂肪:- 骨:2.93 皮膚:3.55
RNA-seq 大脳:1.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:207.10 前立腺:- 卵巣:11.50 精巣:22.20 心臓:37.20 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:27.20        肺:10    膀胱:- 腎臓:16.10 下垂体:- 甲状腺:- 副腎:- 膵臓:140.70 乳腺:45.70 唾液腺:-
GeneChip 子宮:8.44 胎盤:8.77 前立腺:7.26 卵巣:8.55 精巣:7.22 心臓:7.84 骨格筋:7.66 食道:- 胃:8.01 腸:7.98 結腸:- 肝臓:7.51 肺:8.42 膀胱:8.23 腎臓:7.60 下垂体:7.11 甲状腺:- 副腎:7.58 膵臓:6.54 乳腺:8.05 唾液腺:7.03
CAGE 子宮:3.68 胎盤:3.57 前立腺:2.74 卵巣:3.63 精巣:2.19 心臓:- 骨格筋:- 食道:- 胃:2.90 腸:3.11 結腸:3.22     肝臓:3.28    肺:3.63 膀胱:3.16 腎臓:- 下垂体:2.58 甲状腺:- 副腎:3.31 膵臓:2.33 乳腺:3.30 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.14 食道:- 胃:- 腸:- 結腸:-     肝臓:2.52        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009615
Gene ID 11491
Unigene ID Mm.276815
Probe set ID 1421859_at  [Mouse430_2]
Ensembl ID ENSMUSG00000052593

オーソログ対応遺伝子

ヒト[3]  NM_003183
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
9034190
9034191
9598327
9755855
9774383
9812885
10187843
10224132
10349636
10375622
10393218
10433800
10523497
10656920
10725249
10799547
10882063
10922068
11032903
11042159
11076861
11108241
11217851
11254358
11733179
11823465
12466851
12477932
12520002
12711607
12773386
12814936
12878595
12904583
14499647
14515145
14610273
14625290
14638693
14673146
14761956
14993236
15066986
15345652
15365312
15574878
15691827
15739225
15782199
15817462
15907280
15923650
15936750
15985531
16054021
16079154
16079176
16141072
16141073
16179345
16199880
16214147
16294222
16332269
16332693
16380418
16438938
16735599
16806063
16809777
16942750
17079736
17169360
17244710
17344430
17371977
17510296
17567983
17572069
17646208
17709479
17804806
17884817
17904861
17982061
18040288
18355445
18356551
18364436
18367087
18625725
18650320
18687778
18713734
18722532
18762577
18799693
18818406
18824549
19005070
19027012
19176481
19201862
19201900
19250983
19258599
19296470
19346138
19426283
19457070
19482949
19494263
19574220
19581512
19704010
19737556
19759332
19767822
19827603
19827604
19846666
19877183
19965619
20026129
20110534
20154226
20194968
20220092
20236926
20359533
20421303
20529858
20603312
20628198
20644114
20800622
20803506
20976004
20976179
20980382
21041656
21079048
21097655
21205794
21267068
21273553
21407195
21411748
21421844
21454673
21519143
21603616
21628404
21666671
21677750
21785222
21828049
21837653
21871134
21900081
22009748
22033402
22055939
22101895
22246777
22246778
22284418
22319556
22357929
22384041
22479555
22565824
22575642
22610140
22623356
22696231
22772468
22898814
22975374
23105116
23147225
23211830
23228566
23251384
23274494
23342154
23348744
23349978
23354118
23563789
23564510
23584255
23639813
23657465
23678045
23732913
23755270
23779109
23801765
23817563
23868980
23888051
23955337
23955714
23979594
24103556
24135057
24140644
24142516
24223177
24227779
24275664
24286866
24336074
24342803
24462774

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030183  B cell differentiation
GO:0007155  cell adhesion
GO:0033627  cell adhesion mediated by integrin
GO:0048870  cell motility
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0002467  germinal center formation
GO:0007229  integrin-mediated signaling pathway
GO:0006509  membrane protein ectodomain proteolysis
GO:0043066  negative regulation of apoptosis
GO:0032717  negative regulation of interleukin-8 production
GO:0007219  Notch signaling pathway
GO:0051088  PMA-inducible membrane protein ectodomain proteolysis
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0051272  positive regulation of cellular component movement
GO:0032722  positive regulation of chemokine production
GO:0031659  positive regulation of cyclin-dependent protein kinase activity during G1/S
GO:0045741  positive regulation of epidermal growth factor receptor activity
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0010820  positive regulation of T cell chemotaxis
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0006508  proteolysis
GO:0033025  regulation of mast cell apoptosis
GO:0042493  response to drug
GO:0055099  response to high density lipoprotein stimulus
GO:0001666  response to hypoxia
GO:0032496  response to lipopolysaccharide
GO:0048536  spleen development
GO:0033077  T cell differentiation in the thymus

Cellular Component

GO:0015629  actin cytoskeleton
GO:0016324  apical plasma membrane
GO:0009986  cell surface
GO:0005911  cell-cell junction
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005925  focal adhesion
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane
GO:0032587  ruffle membrane

Molecular Function

GO:0016787  hydrolase activity
GO:0005178  integrin binding
GO:0005138  interleukin-6 receptor binding
GO:0046872  metal ion binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0030165  PDZ domain binding
GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0017124  SH3 domain binding
GO:0008270  zinc ion binding