a disintegrin and metallopeptidase domain 8

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同義遺伝子名

a disintegrin and metallopeptidase domain 8, CD156 antigen, CD156, A disintegrin and metalloproteinase domain 8, CD156a, Cell surface antigen MS2, E430039A18Rik, Macrophage cysteine-rich glycoprotein, MS2, Adam8, ADAM 8 precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:5.20 小脳:73.70 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:96.40 目:- 動脈:84.40 静脈:- リンパ節:4082.90 末梢血:71.90 脾臓:144.80 胸腺:168 骨髄:1295 脂肪:212.70 骨:425.80 皮膚:31.70
GeneChip 大脳:5.27 小脳:4.81 脳幹:- 脳梁:- 松果体:- 末梢神経:6.13 脊柱:5.26 網膜:5.06 目:5.05 動脈:- 静脈:6.03 リンパ節:8.73 末梢血:- 脾臓:7.99 胸腺:- 骨髄:9.21 脂肪:5.28 骨:8.80 皮膚:6.25
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0.66 網膜:- 目:- 動脈:1.75 静脈:- リンパ節:3.25 末梢血:- 脾臓:2.74 胸腺:2.52 骨髄:- 脂肪:- 骨:4.02 皮膚:1.63
RNA-seq 大脳:0.88 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:69 前立腺:30.90 卵巣:11.50 精巣:7.40 心臓:223.20 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:80.30    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:39.20 唾液腺:-
GeneChip 子宮:7.28 胎盤:6.60 前立腺:4.97 卵巣:8.48 精巣:5.93 心臓:5.36 骨格筋:5.19 食道:- 胃:5.45 腸:5.21 結腸:- 肝臓:4.90 肺:6.89 膀胱:5.24 腎臓:5.04 下垂体:5.54 甲状腺:- 副腎:5.18 膵臓:5.20 乳腺:5.76 唾液腺:6.36
CAGE 子宮:2.35 胎盤:2.81 前立腺:0 卵巣:3.31 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:0.58 結腸:1.11     肝臓:0.64    肺:3.09 膀胱:1.45 腎臓:- 下垂体:1.22 甲状腺:- 副腎:2.64 膵臓:0 乳腺:1.08 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.32 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0043534  blood vessel endothelial cell migration
GO:0000902  cell morphogenesis
GO:0016337  cell-cell adhesion
GO:0007160  cell-matrix adhesion
GO:0071456  cellular response to hypoxia
GO:0006954  inflammatory response
GO:0007229  integrin-mediated signaling pathway
GO:0002523  leukocyte migration during inflammatory response
GO:0048247  lymphocyte chemotaxis
GO:0006944  membrane fusion
GO:0043524  negative regulation of neuron apoptosis
GO:0002675  positive regulation of acute inflammatory response
GO:0045780  positive regulation of bone resorption
GO:0045785  positive regulation of cell adhesion
GO:0002693  positive regulation of cellular extravasation
GO:0050729  positive regulation of inflammatory response
GO:0051044  positive regulation of membrane protein ectodomain proteolysis
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0070245  positive regulation of thymocyte apoptosis
GO:0006508  proteolysis
GO:0022407  regulation of cell-cell adhesion
GO:0045670  regulation of osteoclast differentiation
GO:0048729  tissue morphogenesis

Cellular Component

GO:0071133  alpha9-beta1 integrin-ADAM8 complex
GO:0071065  alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0032127  dense core granule membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0032010  phagolysosome
GO:0005886  plasma membrane
GO:0002102  podosome
GO:0042581  specific granule
GO:0070820  tertiary granule

Molecular Function

GO:0005509  calcium ion binding
GO:0050839  cell adhesion molecule binding
GO:0016787  hydrolase activity
GO:0005178  integrin binding
GO:0046872  metal ion binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0008270  zinc ion binding