adenosine A1 receptor

詳細情報を見る

同義遺伝子名

A1R, A1AR, Adora1, Adenosine A1 receptor, adenosine A1 receptor, BB176431, AI848715

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:208.40 小脳:55.30 脳幹:317.80 脳梁:- 松果体:257.80 末梢神経:- 脊柱:- 網膜:64.30 目:22.80 動脈:168.80 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:125.20 皮膚:23.80
GeneChip 大脳:7.34 小脳:7.72 脳幹:- 脳梁:- 松果体:- 末梢神経:7.30 脊柱:8.04 網膜:5.85 目:5.90 動脈:- 静脈:4.94 リンパ節:5.19 末梢血:- 脾臓:4.88 胸腺:- 骨髄:5.17 脂肪:6.49 骨:5.04 皮膚:5.08
CAGE 大脳:4.35 小脳:- 脳幹:4.21 脳梁:- 松果体:- 末梢神経:- 脊柱:4.42 網膜:- 目:- 動脈:4.00 静脈:- リンパ節:0.71 末梢血:- 脾臓:0 胸腺:0.67 骨髄:- 脂肪:- 骨:0.63 皮膚:0.97
RNA-seq 大脳:10.04 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:55.20 前立腺:- 卵巣:23 精巣:22.20 心臓:55.80 骨格筋:- 食道:- 胃:98.20 腸:- 結腸:-     肝臓:27.20        肺:-    膀胱:- 腎臓:48.40 下垂体:- 甲状腺:112.50 副腎:- 膵臓:56.30 乳腺:49 唾液腺:108
GeneChip 子宮:4.80 胎盤:5.29 前立腺:5.57 卵巣:5.77 精巣:6.45 心臓:5.98 骨格筋:5.27 食道:- 胃:5.80 腸:5.27 結腸:- 肝臓:6.41 肺:5.16 膀胱:5.52 腎臓:5.35 下垂体:5.46 甲状腺:- 副腎:8.19 膵臓:7.11 乳腺:5.48 唾液腺:5.90
CAGE 子宮:0.83 胎盤:0.60 前立腺:1.41 卵巣:2.50 精巣:2.68 心臓:- 骨格筋:- 食道:- 胃:3.09 腸:0.95 結腸:1.11     肝臓:2.23    肺:0.98 膀胱:2.25 腎臓:- 下垂体:2.22 甲状腺:- 副腎:4.57 膵臓:2.97 乳腺:1.45 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.36 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001008533
Gene ID 11539
Unigene ID Mm.298908
Probe set ID 1427331_at  [Mouse430_2]
Ensembl ID ENSMUSG00000042429

オーソログ対応遺伝子

ヒト[4]  NM_000674, NM_001048230
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8157966
8734470
8889548
10318839
10349636
10487528
10536053
10549586
10922068
10993769
11009456
11042159
11076861
11217851
11448841
11470917
11504952
11641103
11704566
11834491
12063302
12193199
12443980
12466851
12475747
12477932
12637351
12793993
12843280
12975523
14529816
14600029
14633239
14744882
14760015
14767772
14960625
15033378
15081797
15272017
15283758
15341591
15343381
15539423
15630442
15637180
15653569
15661449
15772343
15784841
15837119
15858837
15965471
16121125
16141072
16141073
16150954
16172432
16177079
16263804
16299260
16299262
16303857
16343787
16357099
16418301
16517942
16602821
16626672
16679400
16728466
16750195
16788688
16807541
16951167
16987234
17088462
17126319
17353435
17360481
17396131
17428234
17428236
17428973
17438146
17522253
17581137
17728380
17869224
17920622
17921328
17928414
18032734
18056839
18098126
18157140
18178251
18181173
18199602
18256360
18322364
18324658
18340377
18445770
18490761
18562097
18578565
18787641
18789919
18809912
18824766
18838560
18940592
19036889
19066225
19092996
19158311
19190680
19193874
19218506
19221436
19249906
19249907
19276628
19338746
19552606
19592614
19682463
19707555
19741017
19756184
19950175
20065944
20112380
20121416
20132147
20137682
20147550
20176083
20181934
20230919
20363896
20400685
20576036
20598020
20685973
20729330
20810615
20828543
20876230
21170046
21270276
21291865
21460200
21544869
21546445
21557932
21615720
21622845
21677750
21685268
21701065
21743001
21831968
21907719
21917810
21975649
22039302
22160543
22164264
22215671
22269324
22311477
22389722
22449383
22457491
22550063
22695326
22862844
22864185
22874421
22896040
22899189
22956627
23018918
23119057
23613131
23682121
23692951
23812746
23825434
23969284
24043252
24264405

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000186  activation of MAPKK activity
GO:0001973  adenosine receptor signaling pathway
GO:0050890  cognition
GO:0050965  detection of temperature stimulus involved in sensory perception of pain
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0016042  lipid catabolic process
GO:0002674  negative regulation of acute inflammatory response
GO:0043066  negative regulation of apoptosis
GO:0045776  negative regulation of blood pressure
GO:0055118  negative regulation of cardiac muscle contraction
GO:0008285  negative regulation of cell proliferation
GO:0042323  negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0042321  negative regulation of circadian sleep/wake cycle, sleep
GO:0014050  negative regulation of glutamate secretion
GO:0045822  negative regulation of heart contraction
GO:0046888  negative regulation of hormone secretion
GO:0050728  negative regulation of inflammatory response
GO:0002686  negative regulation of leukocyte migration
GO:0050995  negative regulation of lipid catabolic process
GO:0070256  negative regulation of mucus secretion
GO:0032900  negative regulation of neurotrophin production
GO:0032229  negative regulation of synaptic transmission, GABAergic
GO:0051967  negative regulation of synaptic transmission, glutamatergic
GO:0045908  negative regulation of vasodilation
GO:0045777  positive regulation of blood pressure
GO:0045741  positive regulation of epidermal growth factor receptor activity
GO:0032244  positive regulation of nucleoside transport
GO:0002793  positive regulation of peptide secretion
GO:0043268  positive regulation of potassium ion transport
GO:0035307  positive regulation of protein amino acid dephosphorylation
GO:0006612  protein targeting to membrane
GO:0055117  regulation of cardiac muscle contraction
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0003093  regulation of glomerular filtration
GO:0002087  regulation of respiratory gaseous exchange by neurological system process
GO:0048167  regulation of synaptic plasticity
GO:0060087  relaxation of vascular smooth muscle
GO:0001666  response to hypoxia
GO:0007165  signal transduction
GO:0001659  temperature homeostasis

Cellular Component

GO:0032279  asymmetric synapse
GO:0030673  axolemma
GO:0016323  basolateral plasma membrane
GO:0043025  cell soma
GO:0030425  dendrite
GO:0012505  endomembrane system
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0048786  presynaptic active zone
GO:0042734  presynaptic membrane
GO:0043195  terminal button

Molecular Function

GO:0001609  adenosine receptor activity, G-protein coupled
GO:0031683  G-protein beta/gamma-subunit binding
GO:0004930  G-protein coupled receptor activity
GO:0001664  G-protein-coupled receptor binding
GO:0032795  heterotrimeric G-protein binding
GO:0004629  phospholipase C activity
GO:0046982  protein heterodimerization activity
GO:0001883  purine nucleoside binding
GO:0004871  signal transducer activity