adenosine A2a receptor

詳細情報を見る

同義遺伝子名

MGC118414, Adenosine A2a receptor, A2AAR, adenosine A2a receptor, Adora2a, A2aR

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:33 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:- 末梢血:28.80 脾臓:118.50 胸腺:19.80 骨髄:64.10 脂肪:- 骨:175.30 皮膚:-
GeneChip 大脳:7.65 小脳:7.07 脳幹:- 脳梁:- 松果体:- 末梢神経:7.15 脊柱:7.26 網膜:6.95 目:7.19 動脈:- 静脈:7.32 リンパ節:7.71 末梢血:- 脾臓:7.92 胸腺:- 骨髄:7.49 脂肪:7.69 骨:7.30 皮膚:7.31
CAGE 大脳:0.51 小脳:- 脳幹:1.22 脳梁:- 松果体:- 末梢神経:- 脊柱:0.55 網膜:- 目:- 動脈:1.20 静脈:- リンパ節:2.05 末梢血:- 脾臓:1.81 胸腺:1.99 骨髄:- 脂肪:- 骨:1.51 皮膚:0.40
RNA-seq 大脳:5.82 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:14.80 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:8.10 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:- 唾液腺:-
GeneChip 子宮:7.20 胎盤:7.49 前立腺:8.03 卵巣:7.24 精巣:7.12 心臓:7.57 骨格筋:7.36 食道:- 胃:7.26 腸:7.24 結腸:- 肝臓:7.78 肺:7.03 膀胱:7.31 腎臓:7.79 下垂体:7.26 甲状腺:- 副腎:7.44 膵臓:8.97 乳腺:7.28 唾液腺:7.26
CAGE 子宮:0.55 胎盤:0.88 前立腺:0.37 卵巣:0.45 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.58 結腸:0.82     肝臓:1.02    肺:1.62 膀胱:0.57 腎臓:- 下垂体:0.52 甲状腺:- 副腎:1.38 膵臓:1.30 乳腺:0.92 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.85 食道:- 胃:- 腸:- 結腸:-     肝臓:0.81        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009630
Gene ID 11540
Unigene ID Mm.333734
Probe set ID 1460710_at  [Mouse430_2]
Ensembl ID ENSMUSG00000020178

オーソログ対応遺伝子

ヒト[1]  NM_000675
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1438021
1584214
8157966
8738226
8875985
9262401
9269779
10069416
10081981
10349636
10501634
10531422
10536053
10677546
10704492
10771351
10845921
10908627
10934242
10986328
11042159
11076861
11166335
11172060
11217851
11404425
11432985
11719000
11780065
11788390
11826134
12003827
12057906
12057925
12223546
12417646
12451148
12466851
12477932
12538862
12538871
12542668
12624301
12700712
12817016
12832562
12875990
12900046
12947007
12958152
12975473
14573390
14636179
14715520
14720203
14756803
15053963
15161625
15197231
15210754
15450100
15561971
15602504
15634932
15637180
15746085
15769843
15782199
15814735
15827570
15965471
16012197
16012931
16022683
16046619
16123762
16129427
16141072
16141073
16143649
16177079
16280366
16280580
16470403
16476524
16519795
16519887
16539690
16602821
16617164
16622031
16673448
16679400
16728466
16777350
16788688
16916931
16920910
16962565
17007839
17060376
17079665
17088433
17134834
17192438
17293374
17353435
17371980
17396131
17442976
17502665
17505024
17525287
17548612
17601796
17617618
17675570
17720507
17909080
17921328
17940030
17974599
18005343
18025187
18045850
18056839
18163162
18181173
18206127
18300283
18310463
18340377
18354001
18423660
18465770
18536706
18578565
18586241
18625677
18655781
18703794
18709547
18757481
18787641
18800071
18805895
18809912
18849340
18938161
18950865
19036889
19056861
19097273
19158311
19218506
19221436
19234224
19249906
19249907
19262506
19299692
19338746
19342636
19342675
19356442
19395654
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19443488
19508875
19523941
19524941
19525944
19556359
19703429
19707555
19749167
19765599
19785999
19843934
19852993
19858092
19889728
19895201
19940169
19950175
19955361
20039304
20096683
20167656
20227500
20363887
20367749
20427718
20484596
20505145
20548026
20570301
20570711
20576036
20601948
20610844
20639202
20678550
20709859
20798237
20828543
20876230
20926384
20935155
20938208
20940302
21062422
21062644
21130984
21161333
21170046
21183557
21239713
21257926
21267068
21270276
21514428
21593380
21593381
21615720
21622845
21669258
21677750
21693634
21734299
21743001
21816123
21917810
21926236
21949117
22039302
22100661
22116822
22138579
22160543
22164264
22192288
22213208
22262774
22298379
22307907
22308372
22529293
22623741
22639925
22706302
22767233
22792196
22796382
22896040
22947264
23026406
23093781
23225885
23237743
23276608
23285090
23297214
23328845
23349051
23355189
23363775
23364452
23385980
23407968
23413358
23478188
23525711
23555007
23557694
23583933
23585831
23613131
23682121
23712033
23812746
23820821
23843511
23867769
23874883
23922379
23964122
23981568
24043252
24043903
24090652
24145516
24150242
24259572
24312250
24351932
24352507
24448964

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007205  activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
GO:0001973  adenosine receptor signaling pathway
GO:0048143  astrocyte activation
GO:0042755  eating behavior
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007626  locomotory behavior
GO:0051899  membrane depolarization
GO:0046636  negative regulation of alpha-beta T cell activation
GO:0043154  negative regulation of caspase activity
GO:0008285  negative regulation of cell proliferation
GO:0050728  negative regulation of inflammatory response
GO:0040013  negative regulation of locomotion
GO:0043524  negative regulation of neuron apoptosis
GO:0006469  negative regulation of protein kinase activity
GO:0043116  negative regulation of vascular permeability
GO:0048812  neuron projection morphogenesis
GO:0014057  positive regulation of acetylcholine secretion
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0045938  positive regulation of circadian sleep/wake cycle, sleep
GO:0014049  positive regulation of glutamate secretion
GO:0050714  positive regulation of protein secretion
GO:0032230  positive regulation of synaptic transmission, GABAergic
GO:0051968  positive regulation of synaptic transmission, glutamatergic
GO:0060134  prepulse inhibition
GO:0051924  regulation of calcium ion transport
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0060080  regulation of inhibitory postsynaptic membrane potential
GO:0051881  regulation of mitochondrial membrane potential
GO:0014061  regulation of norepinephrine secretion
GO:0048167  regulation of synaptic plasticity
GO:0006355  regulation of transcription, DNA-dependent
GO:0043279  response to alkaloid
GO:0001975  response to amphetamine
GO:0031000  response to caffeine
GO:0007165  signal transduction
GO:0007271  synaptic transmission, cholinergic
GO:0001963  synaptic transmission, dopaminergic
GO:0035249  synaptic transmission, glutamatergic
GO:0042311  vasodilation

Cellular Component

GO:0032279  asymmetric synapse
GO:0030673  axolemma
GO:0030424  axon
GO:0043025  cell soma
GO:0030425  dendrite
GO:0012505  endomembrane system
GO:0016021  integral to membrane
GO:0005882  intermediate filament
GO:0044446  intracellular organelle part
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0048786  presynaptic active zone
GO:0042734  presynaptic membrane

Molecular Function

GO:0001609  adenosine receptor activity, G-protein coupled
GO:0051393  alpha-actinin binding
GO:0019899  enzyme binding
GO:0004930  G-protein coupled receptor activity
GO:0046982  protein heterodimerization activity
GO:0004871  signal transducer activity
GO:0031802  type 5 metabotropic glutamate receptor binding