adrenergic receptor, beta 1

詳細情報を見る

同義遺伝子名

beta-AR, Beta-1 adrenoceptor, Beta-1 adrenergic receptor, beta 1-AR, Beta-1 adrenoreceptor, adrenergic receptor, beta 1, Adrb1, Adrb-1, Adrb1r

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:20.80 小脳:- 脳幹:31.80 脳梁:- 松果体:- 末梢神経:- 脊柱:189.10 網膜:64.30 目:7.60 動脈:253.20 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:19.80 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:6.54 小脳:4.60 脳幹:- 脳梁:- 松果体:- 末梢神経:4.23 脊柱:4.93 網膜:5.99 目:5.15 動脈:- 静脈:4.64 リンパ節:4.45 末梢血:- 脾臓:5.16 胸腺:- 骨髄:4.25 脂肪:5.60 骨:4.19 皮膚:4.19
CAGE 大脳:2.03 小脳:- 脳幹:2.37 脳梁:- 松果体:- 末梢神経:- 脊柱:1.73 網膜:- 目:- 動脈:3.44 静脈:- リンパ節:0.23 末梢血:- 脾臓:1.76 胸腺:0.95 骨髄:- 脂肪:- 骨:0 皮膚:1.20
RNA-seq 大脳:3.59 小脳:3.59 脳幹:3.59 脳梁:3.59 松果体:3.59 末梢神経:3.59 脊柱:3.59 網膜:3.59 目:3.59 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:- 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:-        肺:10    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:13.10 唾液腺:-
GeneChip 子宮:4.37 胎盤:6.36 前立腺:4.29 卵巣:4.24 精巣:4.47 心臓:6.91 骨格筋:4.31 食道:- 胃:4.31 腸:4.33 結腸:- 肝臓:4.31 肺:8.75 膀胱:4.27 腎臓:4.66 下垂体:4.34 甲状腺:- 副腎:4.60 膵臓:5.31 乳腺:4.80 唾液腺:10.31
CAGE 子宮:0.90 胎盤:2.38 前立腺:0.20 卵巣:0.82 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.58 結腸:1.03     肝臓:0.78    肺:4.19 膀胱:0.18 腎臓:- 下垂体:0.86 甲状腺:- 副腎:1.30 膵臓:2.19 乳腺:2.56 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007419
Gene ID 11554
Unigene ID Mm.46797
Probe set ID 1423420_at  [Mouse430_2]
Ensembl ID ENSMUSG00000035283

オーソログ対応遺伝子

ヒト[1]  NM_000684
ラット[1]  NM_012701

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0006915  apoptosis
GO:0050873  brown fat cell differentiation
GO:0002024  diet induced thermogenesis
GO:0042596  fear response
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0005980  glycogen catabolic process
GO:0031649  heat generation
GO:0055088  lipid homeostasis
GO:0007613  memory
GO:0040015  negative regulation of multicellular organism growth
GO:0045986  negative regulation of smooth muscle contraction
GO:0045762  positive regulation of adenylate cyclase activity
GO:0043065  positive regulation of apoptosis
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0045823  positive regulation of heart contraction
GO:0010460  positive regulation of heart rate
GO:0001996  positive regulation of heart rate by epinephrine-norepinephrine
GO:0046878  positive regulation of saliva secretion
GO:0003084  positive regulation of systemic arterial blood pressure
GO:0001997  positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0003061  positive regulation of the force of heart contraction by norepinephrine
GO:0033365  protein localization in organelle
GO:0051924  regulation of calcium ion transport
GO:0060080  regulation of inhibitory postsynaptic membrane potential
GO:0009409  response to cold
GO:0007266  Rho protein signal transduction
GO:0019233  sensory perception of pain
GO:0007165  signal transduction
GO:0002025  vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0042060  wound healing

Cellular Component

GO:0005737  cytoplasm
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0004935  adrenoceptor activity
GO:0031694  alpha-2A adrenergic receptor binding
GO:0004940  beta1-adrenergic receptor activity
GO:0035240  dopamine binding
GO:0008144  drug binding
GO:0051379  epinephrine binding
GO:0004930  G-protein coupled receptor activity
GO:0051380  norepinephrine binding
GO:0030165  PDZ domain binding
GO:0046982  protein heterodimerization activity
GO:0004871  signal transducer activity