advanced glycosylation end product-specific receptor

詳細情報を見る

同義遺伝子名

Rage, RAGE, Ager, Receptor for advanced glycosylation end products

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:19.10 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:94.60 網膜:96.40 目:15.20 動脈:- 静脈:- リンパ節:54 末梢血:- 脾臓:- 胸腺:59.30 骨髄:- 脂肪:- 骨:25 皮膚:15.80
GeneChip 大脳:6.08 小脳:6.03 脳幹:- 脳梁:- 松果体:- 末梢神経:6.09 脊柱:5.99 網膜:6.02 目:6.25 動脈:- 静脈:6.30 リンパ節:6.07 末梢血:- 脾臓:6.28 胸腺:- 骨髄:6.33 脂肪:6.08 骨:6.02 皮膚:6.12
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:- リンパ節:0.42 末梢血:- 脾臓:0.29 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0
RNA-seq 大脳:1.10 小脳:1.10 脳幹:1.10 脳梁:1.10 松果体:1.10 末梢神経:1.10 脊柱:1.10 網膜:1.10 目:1.10 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:- 前立腺:- 卵巣:149.40 精巣:103.50 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:20.10    膀胱:66.20 腎臓:16.10 下垂体:64.60 甲状腺:112.50 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:5.93 胎盤:6.53 前立腺:5.90 卵巣:5.61 精巣:6.11 心臓:6.23 骨格筋:6.19 食道:- 胃:6.12 腸:5.75 結腸:- 肝臓:6.13 肺:13.52 膀胱:6 腎臓:6.35 下垂体:6.28 甲状腺:- 副腎:5.65 膵臓:6.70 乳腺:5.82 唾液腺:6.34
CAGE 子宮:0.44 胎盤:0.77 前立腺:0.37 卵巣:0 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0    肺:6.93 膀胱:0.46 腎臓:- 下垂体:0 甲状腺:- 副腎:0 膵臓:1.30 乳腺:0.20 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007425
Gene ID 11596
Unigene ID Mm.33830
Probe set ID 1420428_at  [Mouse430_2]
Ensembl ID ENSMUSG00000015452

オーソログ対応遺伝子

ヒト[1]  NM_001136, NM_001206929, NM_001206932, NM_001206966, NM_172197
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9224812
10349636
10399917
11042159
11076861
11217851
11353516
11457879
12070776
12167613
12198705
12203917
12466851
12477932
12598893
12651605
12671045
12887690
14568011
14617629
14623906
14688303
14693711
14744997
14767995
15155381
15173891
15341523
15381690
15599399
15699076
15870382
15944249
16037279
16043866
16141072
16141073
16326806
16403440
16407300
16443768
16503878
16606672
16751175
16815028
16873687
16936199
17003481
17023559
17023736
17224333
17241110
17417641
17446934
17456738
17525257
17667983
17761193
17942394
17951314
17960513
18056345
18058943
18079965
18208974
18245563
18245812
18250435
18256352
18302939
18323529
18355449
18367618
18371970
18403730
18420491
18477705
18511846
18539754
18599158
18603587
18606705
18689872
18768885
18948101
18955497
19005067
19164451
19176597
19218854
19299735
19342682
19401390
19411309
19415676
19539695
19541845
19592063
19602045
19627249
19631738
19679874
19767511
19779136
19821765
19901339
19906677
19959710
20015941
20016851
20028966
20124731
20133903
20231695
20333255
20361273
20404919
20407037
20435311
20473308
20507991
20547845
20574008
20600932
20606421
20630999
20631980
20658520
20682624
20682692
20701913
20817881
20923549
20972729
21099228
21126167
21131443
21148126
21209080
21267068
21270403
21276777
21298413
21399623
21412218
21487520
21502377
21512281
21542009
21629785
21680901
21685154
21693575
21828158
21837459
21846974
21884699
21940783
21978883
21980055
21990362
22012330
22052106
22067944
22075646
22198954
22202666
22227007
22239894
22262795
22276098
22318783
22328527
22343220
22367054
22370717
22469986
22470535
22493510
22496883
22505673
22509024
22539295
22543586
22552116
22615109
22622498
22634181
22675199
22698798
22698914
22699121
22745485
22772444
22798221
22804476
22829582
22889845
22892029
22908267
23011593
23108227
23144333
23150674
23172920
23209312
23231807
23269246
23275625
23284645
23288172
23369670
23442498
23507144
23523633
23526218
23526992
23594597
23663738
23677242
23708564
23712426
23729438
23774862
23894348
23899512
23936343
23973487
23975852
23991045
23997170
24081950
24097189
24113348
24115907
24134692
24244627
24260107
24273313
24472555
24474694
24515114
24723555

遺伝子オントロジー  (GO ID)

Biological Process

GO:0055074  calcium ion homeostasis
GO:0050930  induction of positive chemotaxis
GO:0006954  inflammatory response
GO:0007259  JAK-STAT cascade
GO:0007162  negative regulation of cell adhesion
GO:0032966  negative regulation of collagen biosynthetic process
GO:0010596  negative regulation of endothelial cell migration
GO:0001937  negative regulation of endothelial cell proliferation
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0031175  neuron projection development
GO:0043065  positive regulation of apoptosis
GO:0010508  positive regulation of autophagy
GO:0030335  positive regulation of cell migration
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0010763  positive regulation of fibroblast migration
GO:0048146  positive regulation of fibroblast proliferation
GO:0010628  positive regulation of gene expression
GO:0050729  positive regulation of inflammatory response
GO:0043525  positive regulation of neuron apoptosis
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0050727  regulation of inflammatory response

Cellular Component

GO:0030424  axon
GO:0009925  basal plasma membrane
GO:0043025  cell soma
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0050785  advanced glycation end-product receptor activity
GO:0070379  high mobility group box 1 binding
GO:0005515  protein binding