angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

詳細情報を見る

同義遺伝子名

Aogen, Agt, Angiotensinogen precursor, AI265500, Serpina8

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:27.80

小脳:92.10

脳幹:63.60

脳梁:-

松果体:-

末梢神経:57.30

脊柱:94.60

網膜:-

目:-

動脈:-

静脈:-

リンパ節:21.60

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:8.13

小脳:9.38

脳幹:-

脳梁:-

松果体:-

末梢神経:6.81

脊柱:10.68

網膜:6.44

目:6.31

動脈:-

静脈:6.27

リンパ節:6.48

末梢血:-

脾臓:6.11

胸腺:-

骨髄:7.72

脂肪:9.84

骨:7.41

皮膚:6.47

CAGE

大脳:3.18

小脳:-

脳幹:4.73

脳梁:-

松果体:-

末梢神経:-

脊柱:5.02

網膜:-

目:-

動脈:1.06

静脈:-

リンパ節:0.23

末梢血:-

脾臓:0

胸腺:0.27

骨髄:-

脂肪:-

骨:1.97

皮膚:1.67

RNA-seq

大脳:25.79

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:-

卵巣:11.50

精巣:66.50

心臓:-

骨格筋:106.50

食道:-

胃:-

腸:-

結腸:123.40

肝臓:841.70

肺:-

膀胱:-

腎臓:24.20

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:49

唾液腺:324

GeneChip

子宮:6.36

胎盤:8.63

前立腺:6.52

卵巣:9.50

精巣:10.26

心臓:6.97

骨格筋:8.03

食道:-

胃:7.50

腸:7.39

結腸:-

肝臓:12.42

肺:7.17

膀胱:6.58

腎臓:9.15

下垂体:6.24

甲状腺:-

副腎:6.66

膵臓:7.01

乳腺:7.91

唾液腺:11.73

CAGE

子宮:0.74

胎盤:1.58

前立腺:0.63

卵巣:3.69

精巣:4.30

心臓:-

骨格筋:-

食道:-

胃:2.79

腸:2.06

結腸:1.81

肝臓:6.62

肺:0.44

膀胱:1.31

腎臓:-

下垂体:0.70

甲状腺:-

副腎:1.58

膵臓:1.61

乳腺:3.44

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.00

食道:-

胃:-

腸:-

結腸:-

肝臓:145.66

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007428
Gene ID	11606
Unigene ID	Mm.301626
Probe set ID	1423396_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031980

オーソログ対応遺伝子

ヒト[1]	NM_000029
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000227	Angiotensinogen
IPR000215	Protease inhibitor I4, serpin

遺伝子オントロジー (GO ID)

Biological Process

GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0007202	activation of phospholipase C activity
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0003051	angiotensin-mediated drinking behavior
GO:0014824	artery smooth muscle contraction
GO:0048143	astrocyte activation
GO:0001568	blood vessel development
GO:0002035	brain renin-angiotensin system
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0007166	cell surface receptor linked signal transduction
GO:0007160	cell-matrix adhesion
GO:0006883	cellular sodium ion homeostasis
GO:0050663	cytokine secretion
GO:0042756	drinking behavior
GO:0070371	ERK1 and ERK2 cascade
GO:0008065	establishment of blood-nerve barrier
GO:0007588	excretion
GO:0030198	extracellular matrix organization
GO:0048144	fibroblast proliferation
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0042445	hormone metabolic process
GO:0006917	induction of apoptosis
GO:0001822	kidney development
GO:0016525	negative regulation of angiogenesis
GO:0030308	negative regulation of cell growth
GO:0008285	negative regulation of cell proliferation
GO:0010951	negative regulation of endopeptidase activity
GO:0051387	negative regulation of nerve growth factor receptor signaling pathway
GO:0043524	negative regulation of neuron apoptosis
GO:0034104	negative regulation of tissue remodeling
GO:0001543	ovarian follicle rupture
GO:0030432	peristalsis
GO:0010535	positive regulation of activation of JAK2 kinase activity
GO:0045777	positive regulation of blood pressure
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
GO:0010613	positive regulation of cardiac muscle hypertrophy
GO:0043085	positive regulation of catalytic activity
GO:0032270	positive regulation of cellular protein metabolic process
GO:0010873	positive regulation of cholesterol esterification
GO:0010595	positive regulation of endothelial cell migration
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
GO:0003331	positive regulation of extracellular matrix constituent secretion
GO:0045723	positive regulation of fatty acid biosynthetic process
GO:0048146	positive regulation of fibroblast proliferation
GO:0010628	positive regulation of gene expression
GO:0043410	positive regulation of MAPKKK cascade
GO:0040018	positive regulation of multicellular organism growth
GO:0046622	positive regulation of organ growth
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0032930	positive regulation of superoxide release
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0042981	regulation of apoptosis
GO:0008217	regulation of blood pressure
GO:0051924	regulation of calcium ion transport
GO:0010468	regulation of gene expression
GO:0050727	regulation of inflammatory response
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0014061	regulation of norepinephrine secretion
GO:0030162	regulation of proteolysis
GO:0002019	regulation of renal output by angiotensin
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0001999	renal response to blood flow during renin-angiotensin regulation of systemic arterial blood pressure
GO:0002018	renin-angiotensin regulation of aldosterone production
GO:0009409	response to cold
GO:0014873	response to muscle activity involved in regulation of muscle adaptation
GO:0009651	response to salt stress
GO:0051145	smooth muscle cell differentiation
GO:0048659	smooth muscle cell proliferation
GO:0051403	stress-activated MAPK cascade
GO:0070471	uterine smooth muscle contraction
GO:0042310	vasoconstriction
GO:0042311	vasodilation

Cellular Component

GO:0044444	cytoplasmic part
GO:0005615	extracellular space

Molecular Function

GO:0010698	acetyltransferase activator activity
GO:0031701	angiotensin receptor binding
GO:0005179	hormone activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0031702	type 1 angiotensin receptor binding
GO:0031703	type 2 angiotensin receptor binding

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function