thymoma viral proto-oncogene 1

 詳細情報を見る

同義遺伝子名

Protein kinase B, Akt1, PKBalpha, thymoma viral proto-oncogene 1, Thymoma viral proto-oncogene, Rac, RAC-alpha serine/threonine-protein kinase, Akt, AKT1 kinase, C-AKT, RAC-PK-alpha, PKB/Akt

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:125 小脳:- 脳幹:31.80 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:32.10 目:76 動脈:168.80 静脈:- リンパ節:97.20 末梢血:100.60 脾臓:39.50 胸腺:69.20 骨髄:25.60 脂肪:- 骨:125.20 皮膚:71.30
GeneChip 大脳:9.30 小脳:8.93 脳幹:- 脳梁:- 松果体:- 末梢神経:9.76 脊柱:9.81 網膜:8.78 目:9.03 動脈:- 静脈:9.78 リンパ節:9.60 末梢血:- 脾臓:9.68 胸腺:- 骨髄:9.34 脂肪:8.88 骨:9.37 皮膚:8.73
CAGE 大脳:3.83 小脳:- 脳幹:4.06 脳梁:- 松果体:- 末梢神経:- 脊柱:4.14 網膜:- 目:- 動脈:3.76 静脈:- リンパ節:3.16 末梢血:- 脾臓:3.70 胸腺:3.80 骨髄:- 脂肪:- 骨:3.96 皮膚:3.72
RNA-seq 大脳:41.18 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:87.20 胎盤:41.40 前立腺:- 卵巣:11.50 精巣:7.40 心臓:93 骨格筋:35.50 食道:- 胃:32.70 腸:- 結腸:158.60     肝臓:36.20        肺:180.80    膀胱:66.20 腎臓:40.30 下垂体:374.60 甲状腺:224.90 副腎:- 膵臓:65.70 乳腺:215.50 唾液腺:108
GeneChip 子宮:9.96 胎盤:10.07 前立腺:9.67 卵巣:10.06 精巣:8.08 心臓:9.77 骨格筋:8.89 食道:- 胃:9.83 腸:9.58 結腸:- 肝臓:8.61 肺:9.81 膀胱:9.29 腎臓:8.68 下垂体:9.27 甲状腺:- 副腎:10.01 膵臓:10.17 乳腺:9.53 唾液腺:9.66
CAGE 子宮:4.14 胎盤:4.93 前立腺:4.36 卵巣:4.07 精巣:2.85 心臓:- 骨格筋:- 食道:- 胃:4.65 腸:3.60 結腸:4.01     肝臓:3.96    肺:4.26 膀胱:3.98 腎臓:- 下垂体:3.68 甲状腺:- 副腎:4.43 膵臓:5.20 乳腺:5.41 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:9.47 食道:- 胃:- 腸:- 結腸:-     肝臓:8.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_001165894
Gene ID 11651
Unigene ID Mm.6645
Probe set ID 1416657_at  [Mouse430_2]
Ensembl ID ENSMUSG00000001729

オーソログ対応遺伝子

ヒト[3]  NM_001014431, NM_001014432, NM_005163
ラット [0]  

染色体

12F1  [113,892,032  -  113,913,095]

遺伝子ファミリー (Interpro ID)

IPR000961  AGC-kinase, C-terminal
IPR001849  Pleckstrin homology
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

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23884910
23904165
23907468
23919516
23921086
23921150
23924632
23935948
23968884
23974039
23989801
24015256
24052256
24053326
24056770
24069385
24082083
24085786
24086577
24106278
24126057
24126911
24129178
24149576
24165986
24169049
24188879
24200692
24209762
24218567
24235146
24270425
24275666
24296716
24297901
24316214
24333429
24333443
24342610
24355921
24371503
24403577
24431450
24446434
24462873
24464560
24469394
24505141
24560271
24567360
24605828
24634221
24642468
24667640
24692549
24733849
24777252
24806753

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006924  activation-induced cell death of T cells
GO:0007568  aging
GO:0042640  anagen
GO:0006915  apoptosis
GO:0008637  apoptotic mitochondrial changes
GO:0005975  carbohydrate metabolic process
GO:0008643  carbohydrate transport
GO:0030030  cell projection organization
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071363  cellular response to growth factor stimulus
GO:0071456  cellular response to hypoxia
GO:0032869  cellular response to insulin stimulus
GO:0071260  cellular response to mechanical stimulus
GO:0007010  cytoskeleton organization
GO:0007281  germ cell development
GO:0042593  glucose homeostasis
GO:0006006  glucose metabolic process
GO:0015758  glucose transport
GO:0005978  glycogen biosynthetic process
GO:0060709  glycogen cell development involved in embryonic placenta development
GO:0005977  glycogen metabolic process
GO:0006954  inflammatory response
GO:0008286  insulin receptor signaling pathway
GO:0048009  insulin-like growth factor receptor signaling pathway
GO:0060716  labyrinthine layer blood vessel development
GO:0001893  maternal placenta development
GO:0007275  multicellular organismal development
GO:0032287  myelin maintenance in the peripheral nervous system
GO:0043066  negative regulation of apoptosis
GO:0010507  negative regulation of autophagy
GO:0043154  negative regulation of caspase activity
GO:0045792  negative regulation of cell size
GO:0010951  negative regulation of endopeptidase activity
GO:0031999  negative regulation of fatty acid beta-oxidation
GO:0046329  negative regulation of JNK cascade
GO:0010748  negative regulation of plasma membrane long-chain fatty acid transport
GO:0006469  negative regulation of protein kinase activity
GO:0045861  negative regulation of proteolysis
GO:0090201  negative regulation of release of cytochrome c from mitochondria
GO:0007399  nervous system development
GO:0001649  osteoblast differentiation
GO:0018105  peptidyl-serine phosphorylation
GO:0016310  phosphorylation
GO:0043065  positive regulation of apoptosis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0030307  positive regulation of cell growth
GO:0032270  positive regulation of cellular protein metabolic process
GO:0031659  positive regulation of cyclin-dependent protein kinase activity during G1/S
GO:0090004  positive regulation of establishment of protein localization in plasma membrane
GO:0045600  positive regulation of fat cell differentiation
GO:0046326  positive regulation of glucose import
GO:0010907  positive regulation of glucose metabolic process
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0046889  positive regulation of lipid biosynthetic process
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0051000  positive regulation of nitric-oxide synthase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0010765  positive regulation of sodium ion transport
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045907  positive regulation of vasoconstriction
GO:0006468  protein amino acid phosphorylation
GO:0030163  protein catabolic process
GO:0000060  protein import into nucleus, translocation
GO:0043491  protein kinase B signaling cascade
GO:0016567  protein ubiquitination
GO:0030334  regulation of cell migration
GO:0005979  regulation of glycogen biosynthetic process
GO:0010975  regulation of neuron projection development
GO:0032880  regulation of protein localization
GO:0006417  regulation of translation
GO:0034405  response to fluid shear stress
GO:0032094  response to food
GO:0009725  response to hormone stimulus
GO:0070141  response to UV-A
GO:0007165  signal transduction
GO:0051146  striated muscle cell differentiation
GO:0006412  translation
GO:0006810  transport

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0015630  microtubule cytoskeleton
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0005819  spindle

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0030235  nitric-oxide synthase regulator activity
GO:0000166  nucleotide binding
GO:0005547  phosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325  phosphatidylinositol-3,4-bisphosphate binding
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0005080  protein kinase C binding
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups