amyloid beta (A4) precursor protein

詳細情報を見る

同義遺伝子名

AG, ABPP, AL024401, protease nexin II, appican, Amyloid beta A4 protein precursor, E030013M08Rik, Alzheimer disease amyloid protein homolog, Cvap, Adap, APP, App, betaAPP, Amyloidogenic glycoprotein, Abeta, amyloid beta (A4) precursor protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:12.65 小脳:12.82 脳幹:- 脳梁:- 松果体:- 末梢神経:12.06 脊柱:12.88 網膜:9.71 目:10.70 動脈:- 静脈:11.76 リンパ節:11.04 末梢血:- 脾臓:9.90 胸腺:- 骨髄:9.54 脂肪:10.54 骨:9.98 皮膚:11.33
CAGE 大脳:5.98 小脳:- 脳幹:6.20 脳梁:- 松果体:- 末梢神経:- 脊柱:6.23 網膜:- 目:- 動脈:4.63 静脈:- リンパ節:4.44 末梢血:- 脾臓:3.77 胸腺:2.99 骨髄:- 脂肪:- 骨:3.97 皮膚:5.18
RNA-seq 大脳:288.53 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST nodata
GeneChip 子宮:11.61 胎盤:11.16 前立腺:10.35 卵巣:10.98 精巣:9.38 心臓:10.07 骨格筋:9.76 食道:- 胃:11.39 腸:11.21 結腸:- 肝臓:8.75 肺:12.53 膀胱:11.61 腎臓:12.37 下垂体:11.97 甲状腺:- 副腎:10.92 膵臓:10.28 乳腺:10.83 唾液腺:10.33
CAGE 子宮:5.04 胎盤:5.11 前立腺:5.29 卵巣:4.65 精巣:2.41 心臓:- 骨格筋:- 食道:- 胃:5.00 腸:4.33 結腸:5.09     肝臓:3.97    肺:5.80 膀胱:5.29 腎臓:- 下垂体:5.69 甲状腺:- 副腎:4.79 膵臓:4.75 乳腺:4.83 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:15.74 食道:- 胃:- 腸:- 結腸:-     肝臓:13.04        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007471
Gene ID 11820
Unigene ID -
Probe set ID 1420621_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022892

オーソログ対応遺伝子

ヒト[21]  NM_000484, NM_001136016, NM_001136129, NM_001136130, NM_001136131, NM_001204301, NM_001204302, NM_001204303, NM_201413, NM_201414
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0008344  adult locomotory behavior
GO:0006915  apoptosis
GO:0008088  axon cargo transport
GO:0016199  axon midline choice point recognition
GO:0007409  axonogenesis
GO:0007155  cell adhesion
GO:0006878  cellular copper ion homeostasis
GO:0008203  cholesterol metabolic process
GO:0048669  collateral sprouting in the absence of injury
GO:0016358  dendrite development
GO:0006897  endocytosis
GO:0030198  extracellular matrix organization
GO:0030900  forebrain development
GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0007626  locomotory behavior
GO:0007617  mating behavior
GO:0006378  mRNA polyadenylation
GO:0045665  negative regulation of neuron differentiation
GO:0010466  negative regulation of peptidase activity
GO:0050885  neuromuscular process controlling balance
GO:0051402  neuron apoptosis
GO:0031175  neuron projection development
GO:0016322  neuron remodeling
GO:0007219  Notch signaling pathway
GO:0010971  positive regulation of G2/M transition of mitotic cell cycle
GO:0045931  positive regulation of mitotic cell cycle
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0007176  regulation of epidermal growth factor receptor activity
GO:0010468  regulation of gene expression
GO:0040014  regulation of multicellular organism growth
GO:0043393  regulation of protein binding
GO:0050803  regulation of synapse structure and activity
GO:0006417  regulation of translation
GO:0006979  response to oxidative stress
GO:0051563  smooth endoplasmic reticulum calcium ion homeostasis
GO:0001967  suckling behavior
GO:0051124  synaptic growth at neuromuscular junction
GO:0008542  visual learning

Cellular Component

GO:0045177  apical part of cell
GO:0030424  axon
GO:0009986  cell surface
GO:0035253  ciliary rootlet
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0031594  neuromuscular junction
GO:0043005  neuron projection
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0051233  spindle midzone

Molecular Function

GO:0033130  acetylcholine receptor binding
GO:0003677  DNA binding
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0030414  peptidase inhibitor activity
GO:0005515  protein binding
GO:0051425  PTB domain binding
GO:0005102  receptor binding
GO:0004867  serine-type endopeptidase inhibitor activity
GO:0046914  transition metal ion binding