ataxia telangiectasia mutated homolog (human)

同義遺伝子名

Ataxia telangiectasia mutated homolog, C030026E19Rik, ataxia telangiectasia mutated homolog (human), A-T, mutated homolog, AI256621, Atm, Serine-protein kinase ATM

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:36.50

小脳:36.80

脳幹:-

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:38

動脈:-

静脈:-

リンパ節:21.60

末梢血:143.80

脾臓:171.20

胸腺:39.50

骨髄:-

脂肪:-

骨:-

皮膚:7.90

GeneChip

大脳:6.73

小脳:7.01

脳幹:-

脳梁:-

松果体:-

末梢神経:7.34

脊柱:6.49

網膜:6.34

目:6.20

動脈:-

静脈:6.81

リンパ節:8.55

末梢血:-

脾臓:8.65

胸腺:-

骨髄:7.41

脂肪:6.97

骨:7.22

皮膚:7.57

CAGE

大脳:2.92

小脳:-

脳幹:2.47

脳梁:-

松果体:-

末梢神経:-

脊柱:2.84

網膜:-

目:-

動脈:3.16

静脈:-

リンパ節:4.32

末梢血:-

脾臓:3.21

胸腺:3.40

骨髄:-

脂肪:-

骨:2.19

皮膚:2.74

RNA-seq

大脳:0.99

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:130.90

胎盤:-

前立腺:61.80

卵巣:46

精巣:66.50

心臓:-

骨格筋:142

食道:-

胃:-

腸:-

結腸:17.60

肝臓:9.10

肺:20.10

膀胱:-

腎臓:16.10

下垂体:103.30

甲状腺:-

副腎:-

膵臓:75.10

乳腺:19.60

唾液腺:-

GeneChip

子宮:7.98

胎盤:5.92

前立腺:8.22

卵巣:7.49

精巣:6.50

心臓:6.53

骨格筋:6.65

食道:-

胃:7.03

腸:7.49

結腸:-

肝臓:6.85

肺:6.67

膀胱:7.57

腎臓:6.86

下垂体:7.66

甲状腺:-

副腎:7.30

膵臓:6.73

乳腺:7.36

唾液腺:7.44

CAGE

子宮:3.13

胎盤:2.12

前立腺:2.94

卵巣:3.11

精巣:2.85

心臓:-

骨格筋:-

食道:-

胃:2.36

腸:2.33

結腸:2.50

肝臓:2.60

肺:2.99

膀胱:3.17

腎臓:-

下垂体:3.35

甲状腺:-

副腎:2.92

膵臓:3.27

乳腺:3.00

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.32

食道:-

胃:-

腸:-

結腸:-

肝臓:2.35

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007499
Gene ID	11920
Unigene ID	Mm.5088
Probe set ID	1421205_at [Mouse430_2]
Ensembl ID	ENSMUSG00000034218

オーソログ対応遺伝子

ヒト[3]	NM_000051
ラット[1]	NM_001106821

染色体

遺伝子ファミリー (Interpro ID)

IPR000403	Phosphatidylinositol 3-/4-kinase, catalytic
IPR014009	PIK-related kinase
IPR011009	Protein kinase-like domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0007420	brain development
GO:0007049	cell cycle
GO:0007050	cell cycle arrest
GO:0071480	cellular response to gamma radiation
GO:0000077	DNA damage checkpoint
GO:0006975	DNA damage induced protein phosphorylation
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0006281	DNA repair
GO:0007292	female gamete generation
GO:0031572	G2/M transition DNA damage checkpoint
GO:0007507	heart development
GO:0071044	histone mRNA catabolic process
GO:0016572	histone phosphorylation
GO:0042159	lipoprotein catabolic process
GO:0007094	mitotic cell cycle spindle assembly checkpoint
GO:0030889	negative regulation of B cell proliferation
GO:0051402	neuron apoptosis
GO:0048599	oocyte development
GO:0018105	peptidyl-serine phosphorylation
GO:0016310	phosphorylation
GO:0043065	positive regulation of apoptosis
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043525	positive regulation of neuron apoptosis
GO:0002331	pre-B cell allelic exclusion
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0051726	regulation of cell cycle
GO:0006974	response to DNA damage stimulus
GO:0001666	response to hypoxia
GO:0010212	response to ionizing radiation
GO:0001756	somitogenesis
GO:0000723	telomere maintenance

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0005634	nucleus
GO:0005819	spindle

Molecular Function

GO:0016303	1-phosphatidylinositol-3-kinase activity
GO:0005524	ATP binding
GO:0003677	DNA binding
GO:0004677	DNA-dependent protein kinase activity
GO:0035174	histone serine kinase activity
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0046983	protein dimerization activity
GO:0004672	protein kinase activity
GO:0047485	protein N-terminus binding
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

ataxia telangiectasia mutated homolog (human)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function