axin 1

詳細情報を見る

同義遺伝子名

Fused protein, Axin, Kb, knobbly, Fu, MGC132911, fused, kinky, Axis inhibition protein 1, Axin-1, Axin1, AI316800, axin 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:34.70 小脳:18.40 脳幹:127.10 脳梁:- 松果体:257.80 末梢神経:38.20 脊柱:47.30 網膜:96.40 目:76 動脈:- 静脈:- リンパ節:10.80 末梢血:28.80 脾臓:13.20 胸腺:79 骨髄:38.50 脂肪:212.70 骨:37.60 皮膚:71.30
GeneChip 大脳:6.52 小脳:6.84 脳幹:- 脳梁:- 松果体:- 末梢神経:6.64 脊柱:6.64 網膜:6.07 目:6.14 動脈:- 静脈:6.77 リンパ節:7.30 末梢血:- 脾臓:7.29 胸腺:- 骨髄:7.07 脂肪:6.63 骨:6.82 皮膚:6.68
CAGE 大脳:2.48 小脳:- 脳幹:1.93 脳梁:- 松果体:- 末梢神経:- 脊柱:2.35 網膜:- 目:- 動脈:2.31 静脈:- リンパ節:2.62 末梢血:- 脾臓:2.84 胸腺:3.14 骨髄:- 脂肪:- 骨:3.02 皮膚:2.98
RNA-seq 大脳:3.79 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:27.60 前立腺:- 卵巣:68.90 精巣:44.30 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:110.90 結腸:88.10     肝臓:-        肺:70.30    膀胱:- 腎臓:40.30 下垂体:490.90 甲状腺:112.50 副腎:- 膵臓:28.10 乳腺:71.80 唾液腺:54
GeneChip 子宮:7.20 胎盤:7 前立腺:6.79 卵巣:6.69 精巣:7.54 心臓:6.89 骨格筋:6.82 食道:- 胃:7.08 腸:7.21 結腸:- 肝臓:6.98 肺:6.79 膀胱:6.83 腎臓:7.05 下垂体:7.11 甲状腺:- 副腎:6.54 膵臓:6.78 乳腺:6.70 唾液腺:6.33
CAGE 子宮:2.84 胎盤:2.59 前立腺:2.57 卵巣:2.89 精巣:3.25 心臓:- 骨格筋:- 食道:- 胃:3.00 腸:2.56 結腸:2.88     肝臓:2.51    肺:2.52 膀胱:2.68 腎臓:- 下垂体:2.87 甲状腺:- 副腎:2.73 膵臓:2.75 乳腺:2.49 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.13 食道:- 胃:- 腸:- 結腸:-     肝臓:2.89        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001159598
Gene ID 12005
Unigene ID Mm.23684
Probe set ID 1426967_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024182

オーソログ対応遺伝子

ヒト[2]  NM_003502, NM_181050
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0032147  activation of protein kinase activity
GO:0007628  adult walking behavior
GO:0006915  apoptosis
GO:0048318  axial mesoderm development
GO:0048320  axial mesoderm formation
GO:0008219  cell death
GO:0043623  cellular protein complex assembly
GO:0071407  cellular response to organic cyclic substance
GO:0031122  cytoplasmic microtubule organization
GO:0007368  determination of left/right symmetry
GO:0009950  dorsal/ventral axis specification
GO:0009953  dorsal/ventral pattern formation
GO:0048048  embryonic eye morphogenesis
GO:0060272  embryonic skeletal joint morphogenesis
GO:0034101  erythrocyte homeostasis
GO:0021797  forebrain anterior/posterior pattern formation
GO:0020027  hemoglobin metabolic process
GO:0001701  in utero embryonic development
GO:0007275  multicellular organismal development
GO:0055001  muscle cell development
GO:0045599  negative regulation of fat cell differentiation
GO:0051248  negative regulation of protein metabolic process
GO:0034244  negative regulation of RNA elongation from RNA polymerase II promoter
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0050877  neurological system process
GO:0006913  nucleocytoplasmic transport
GO:0030910  olfactory placode formation
GO:0001743  optic placode formation
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045732  positive regulation of protein catabolic process
GO:0045860  positive regulation of protein kinase activity
GO:0031398  positive regulation of protein ubiquitination
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0051443  positive regulation of ubiquitin-protein ligase activity
GO:0030163  protein catabolic process
GO:0051260  protein homooligomerization
GO:0000209  protein polyubiquitination
GO:0001932  regulation of protein amino acid phosphorylation
GO:0007605  sensory perception of sound
GO:0016055  Wnt receptor signaling pathway
GO:0021881  Wnt receptor signaling pathway involved in forebrain neuron fate commitment
GO:0060070  Wnt receptor signaling pathway through beta-catenin
GO:0060823  Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005881  cytoplasmic microtubule
GO:0031410  cytoplasmic vesicle
GO:0005622  intracellular
GO:0016328  lateral plasma membrane
GO:0016020  membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0043234  protein complex

Molecular Function

GO:0070016  armadillo repeat domain binding
GO:0008013  beta-catenin binding
GO:0019899  enzyme binding
GO:0005096  GTPase activator activity
GO:0070411  I-SMAD binding
GO:0042802  identical protein binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0032947  protein complex scaffold
GO:0019904  protein domain specific binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0043621  protein self-association
GO:0070412  R-SMAD binding
GO:0004871  signal transducer activity
GO:0046332  SMAD binding
GO:0031625  ubiquitin protein ligase binding