axin2

詳細情報を見る

同義遺伝子名

Axil, Conductin, Axin-like protein, axin2, Axin2, Axin-2, Axis inhibition protein 2, Axi1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:69.50 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:47.30 網膜:32.10 目:7.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:29.60 骨髄:- 脂肪:- 骨:12.50 皮膚:39.60
GeneChip 大脳:4.46 小脳:4.53 脳幹:- 脳梁:- 松果体:- 末梢神経:4.46 脊柱:4.44 網膜:4.44 目:4.42 動脈:- 静脈:4.42 リンパ節:4.39 末梢血:- 脾臓:4.12 胸腺:- 骨髄:4.08 脂肪:4.65 骨:3.98 皮膚:4.48
CAGE 大脳:2.70 小脳:- 脳幹:2.08 脳梁:- 松果体:- 末梢神経:- 脊柱:2.04 網膜:- 目:- 動脈:2.60 静脈:- リンパ節:2.26 末梢血:- 脾臓:1.27 胸腺:2.15 骨髄:- 脂肪:- 骨:1.69 皮膚:3.27
RNA-seq 大脳:2.41 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:57.50 精巣:- 心臓:37.20 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:8.10 下垂体:258.30 甲状腺:- 副腎:- 膵臓:9.40 乳腺:6.50 唾液腺:-
GeneChip 子宮:4.62 胎盤:4.54 前立腺:4.38 卵巣:4.58 精巣:4.29 心臓:4.55 骨格筋:4.15 食道:- 胃:4.43 腸:4.85 結腸:- 肝臓:4.45 肺:4.37 膀胱:4.12 腎臓:4.22 下垂体:4.71 甲状腺:- 副腎:4.42 膵臓:4.30 乳腺:4.19 唾液腺:4.18
CAGE 子宮:3.53 胎盤:2.32 前立腺:2.35 卵巣:2.98 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:3.14 結腸:3.67     肝臓:2.26    肺:2.67 膀胱:2.40 腎臓:- 下垂体:2.77 甲状腺:- 副腎:3.48 膵臓:2.33 乳腺:1.34 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.19 食道:- 胃:- 腸:- 結腸:-     肝臓:1.98        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_015732
Gene ID 12006
Unigene ID Mm.71710
Probe set ID 1421341_at  [Mouse430_2]
Ensembl ID ENSMUSG00000000142

オーソログ対応遺伝子

ヒト[1]  NM_004655
ラット[1]  NM_024355

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9554852
10049590
10349636
11042159
11076861
11217851
11336703
11809808
11809809
11829488
12466851
12477932
12636920
12798297
12923052
14623818
15042511
15057752
15170214
15367660
15511637
15527894
15545629
15731404
15755804
15769945
15782199
15790973
15800025
15857914
15899843
16107537
16127714
16141072
16141073
16168404
16169491
16291790
16341242
16459298
16510873
16516838
16601693
16602821
16678101
16769906
16815967
17013874
17095659
17113065
17123792
17150208
17198701
17295603
17331723
17360769
17362910
17596282
17644613
17681174
17687036
17785439
17855428
17881490
17904116
17916349
17951031
18000065
18045842
18083923
18157121
18250098
18287559
18351662
18367164
18367557
18385740
18397997
18403408
18448089
18452912
18480159
18480165
18489003
18505822
18563716
18708576
18775421
18776145
18927154
18927156
18957545
19036983
19060336
19093031
19116665
19149881
19165927
19233133
19268448
19364920
19394326
19530172
19539783
19571879
19591821
19596317
19619491
19623616
19653310
19690384
19701191
19718259
19720827
19737815
19769959
19779553
19805295
19806668
19841259
19877272
19884258
19890917
19906857
19906864
19913006
19924825
19932774
19939939
20027618
20107508
20122913
20145239
20159597
20160075
20185815
20200943
20211162
20237272
20300119
20308569
20346939
20359476
20427820
20454682
20501936
20532162
20547147
20569694
20627076
20630950
20637749
20660756
20883686
20890044
20965161
20980404
20981831
21049041
21108844
21113151
21185284
21203428
21205789
21246660
21256124
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21303850
21375603
21384471
21402740
21452227
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21490069
21502507
21523854
21539826
21541292
21554866
21555575
21600200
21606200
21636786
21652647
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21654186
21664580
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21690300
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21706018
21750544
21752936
21757651
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21806977
21841791
21858009
21896628
21925491
21935430
21936019
21982234
21991325
22022457
22232070
22322943
22351753
22365545
22366192
22457761
22461561
22479388
22564414
22575959
22627288
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22745311
22753148
22766025
22771246
22819339
22863533
22939930
22960283
23085236
23095882
23123965
23190887
23260145
23275340
23293290
23300083
23302695
23334328
23341776
23354049
23364326
23396189
23431057
23444352
23449471
23454480
23469192
23475960
23487311
23523683
23562159
23589866
23606270
23614009
23616926
23637336
23645682
23648512
23671110
23727932
23760955
23863479
23863482
23871604
23884445
23936395
23940359
24012369
24045232
24055172
24055345
24139799
24151333
24161848
24191021
24204695
24251807
24260306
24311688
24315444
24394376
24463605
24553287

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030282  bone mineralization
GO:0008219  cell death
GO:0008283  cell proliferation
GO:0034613  cellular protein localization
GO:0071407  cellular response to organic cyclic substance
GO:0003413  chondrocyte differentiation involved in endochondral bone morphogenesis
GO:0009950  dorsal/ventral axis specification
GO:0001957  intramembranous ossification
GO:0043570  maintenance of DNA repeat elements
GO:0048255  mRNA stabilization
GO:0007275  multicellular organismal development
GO:0008285  negative regulation of cell proliferation
GO:0045668  negative regulation of osteoblast differentiation
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0042476  odontogenesis
GO:0010942  positive regulation of cell death
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0070602  regulation of centromeric sister chromatid cohesion
GO:0032423  regulation of mismatch repair
GO:0006355  regulation of transcription, DNA-dependent
GO:0030111  regulation of Wnt receptor signaling pathway
GO:0001756  somitogenesis
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0005938  cell cortex
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005881  cytoplasmic microtubule
GO:0005622  intracellular
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0043234  protein complex

Molecular Function

GO:0070016  armadillo repeat domain binding
GO:0008013  beta-catenin binding
GO:0019899  enzyme binding
GO:0005096  GTPase activator activity
GO:0070411  I-SMAD binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004871  signal transducer activity
GO:0031625  ubiquitin protein ligase binding