bone morphogenetic protein 2

詳細情報を見る

同義遺伝子名

Bmp2a, bone morphogenetic protein 2, Bmp-2, AI467020, BMP-2A, Bmp2, Bone morphogenetic protein 2 precursor, BMP-2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:158.90

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:32.10

目:15.20

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:39.50

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:39.60

GeneChip

大脳:5.69

小脳:4.45

脳幹:-

脳梁:-

松果体:-

末梢神経:4.57

脊柱:5.72

網膜:8.16

目:7.68

動脈:-

静脈:7.02

リンパ節:6.81

末梢血:-

脾臓:7.63

胸腺:-

骨髄:5.84

脂肪:5.41

骨:6.82

皮膚:9

CAGE

大脳:0.58

小脳:-

脳幹:0.59

脳梁:-

松果体:-

末梢神経:-

脊柱:1.17

網膜:-

目:-

動脈:1.53

静脈:-

リンパ節:1.64

末梢血:-

脾臓:1.66

胸腺:0.67

骨髄:-

脂肪:-

骨:1.97

皮膚:2.62

RNA-seq

大脳:0.92

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:30.90

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:35.20

肝臓:36.20

肺:-

膀胱:66.20

腎臓:8.10

下垂体:-

甲状腺:112.50

副腎:-

膵臓:-

乳腺:3.30

唾液腺:-

GeneChip

子宮:5.84

胎盤:5.86

前立腺:6.07

卵巣:7.49

精巣:4.44

心臓:5.67

骨格筋:5.74

食道:-

胃:8.96

腸:8.65

結腸:-

肝臓:8.05

肺:6.13

膀胱:9.81

腎臓:5.13

下垂体:5.68

甲状腺:-

副腎:6.95

膵臓:4.66

乳腺:5.41

唾液腺:5.05

CAGE

子宮:1.41

胎盤:2.08

前立腺:1.35

卵巣:2.34

精巣:0

心臓:-

骨格筋:-

食道:-

胃:3.57

腸:1.99

結腸:2.81

肝臓:2.78

肺:1.17

膀胱:3.70

腎臓:-

下垂体:0.99

甲状腺:-

副腎:1.87

膵臓:0

乳腺:0.32

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.36

食道:-

胃:-

腸:-

結腸:-

肝臓:4.50

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007553
Gene ID	12156
Unigene ID	Mm.103205
Probe set ID	1423635_at [Mouse430_2]
Ensembl ID	ENSMUSG00000027358

オーソログ対応遺伝子

ヒト[2]	NM_001200
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0060128	adrenocorticotropin hormone secreting cell differentiation
GO:0003181	atrioventricular valve morphogenesis
GO:0030509	BMP signaling pathway
GO:0003130	BMP signaling pathway involved in heart induction
GO:0030282	bone mineralization
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0035051	cardiac cell differentiation
GO:0060317	cardiac epithelial to mesenchymal transition
GO:0055007	cardiac muscle cell differentiation
GO:0055008	cardiac muscle tissue morphogenesis
GO:0051216	cartilage development
GO:0030154	cell differentiation
GO:0045165	cell fate commitment
GO:0071363	cellular response to growth factor stimulus
GO:0071407	cellular response to organic cyclic substance
GO:0002062	chondrocyte differentiation
GO:0009790	embryonic development
GO:0035054	embryonic heart tube anterior/posterior pattern formation
GO:0003203	endocardial cushion morphogenesis
GO:0001837	epithelial to mesenchymal transition
GO:0040007	growth
GO:0007507	heart development
GO:0001701	in utero embryonic development
GO:0048839	inner ear development
GO:0048762	mesenchymal cell differentiation
GO:0060485	mesenchyme development
GO:0007275	multicellular organismal development
GO:0032348	negative regulation of aldosterone biosynthetic process
GO:0051042	negative regulation of calcium-independent cell-cell adhesion
GO:0045786	negative regulation of cell cycle
GO:0008285	negative regulation of cell proliferation
GO:0010629	negative regulation of gene expression
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010894	negative regulation of steroid biosynthetic process
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development
GO:0007219	Notch signaling pathway
GO:0042475	odontogenesis of dentine-containing tooth
GO:0009887	organ morphogenesis
GO:0001503	ossification
GO:0001649	osteoblast differentiation
GO:0055114	oxidation reduction
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0060039	pericardium development
GO:0043065	positive regulation of apoptosis
GO:0048711	positive regulation of astrocyte differentiation
GO:0030501	positive regulation of bone mineralization
GO:0045597	positive regulation of cell differentiation
GO:0030335	positive regulation of cell migration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0045600	positive regulation of fat cell differentiation
GO:0010628	positive regulation of gene expression
GO:0043410	positive regulation of MAPKKK cascade
GO:0050769	positive regulation of neurogenesis
GO:0045666	positive regulation of neuron differentiation
GO:0042482	positive regulation of odontogenesis
GO:0045778	positive regulation of ossification
GO:0045669	positive regulation of osteoblast differentiation
GO:0033690	positive regulation of osteoblast proliferation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010922	positive regulation of phosphatase activity
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0060804	positive regulation of WNT receptor signaling pathway by BMP signaling pathway
GO:0006468	protein amino acid phosphorylation
GO:0031648	protein destabilization
GO:0006029	proteoglycan metabolic process
GO:0042487	regulation of odontogenesis of dentine-containing tooth
GO:0006355	regulation of transcription, DNA-dependent
GO:0001666	response to hypoxia
GO:0060395	SMAD protein signal transduction
GO:0021537	telencephalon development
GO:0021978	telencephalon regionalization
GO:0060129	thyroid stimulating hormone secreting cell differentiation
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0031988	membrane-bounded vesicle
GO:0043234	protein complex

Molecular Function

GO:0070700	BMP receptor binding
GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0019211	phosphatase activator activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0005102	receptor binding
GO:0004745	retinol dehydrogenase activity
GO:0046332	SMAD binding

bone morphogenetic protein 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function