complement component 3

 詳細情報を見る

同義遺伝子名

complement factor 3, acylation stimulating protein, C3, HSE-MSF, AI255234, complement component 3, Complement C3 precursor

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:5.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:75.60 末梢血:100.60 脾臓:184.30 胸腺:98.80 骨髄:179.50 脂肪:- 骨:964.40 皮膚:126.70
GeneChip 大脳:5.47 小脳:4.33 脳幹:- 脳梁:- 松果体:- 末梢神経:6.24 脊柱:8.29 網膜:4.34 目:5.04 動脈:- 静脈:7.74 リンパ節:13.51 末梢血:- 脾臓:12.45 胸腺:- 骨髄:11.38 脂肪:12.10 骨:11.02 皮膚:8.47
CAGE nodata
RNA-seq 大脳:43.67 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:305.40 胎盤:41.40 前立腺:- 卵巣:11.50 精巣:7.40 心臓:18.60 骨格筋:745.70 食道:- 胃:- 腸:- 結腸:35.20     肝臓:2506.90        肺:271.10    膀胱:330.90 腎臓:8.10 下垂体:- 甲状腺:112.50 副腎:- 膵臓:75.10 乳腺:81.60 唾液腺:432
GeneChip 子宮:13.90 胎盤:7.86 前立腺:9.22 卵巣:12.80 精巣:7.33 心臓:10.41 骨格筋:10.40 食道:- 胃:9.29 腸:8.50 結腸:- 肝臓:14.35 肺:12.65 膀胱:11.50 腎臓:7.87 下垂体:5.58 甲状腺:- 副腎:10.52 膵臓:10.21 乳腺:12.46 唾液腺:8.87
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:8.80 食道:- 胃:- 腸:- 結腸:-     肝臓:1092.25        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_009778
Gene ID 12266
Unigene ID Mm.19131
Probe set ID 1423954_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024164

オーソログ対応遺伝子

ヒト[1]  NM_000064
ラット[1]  NM_000064

染色体

-

遺伝子ファミリー (Interpro ID)

IPR018081  Anaphylatoxin
IPR000020  Anaphylatoxin/fibulin
IPR001840  Complement C3a/C4a/C5a anaphylatoxin
IPR001134  Netrin domain
IPR018933  Netrin module, non-TIMP type
IPR008993  TIMP-like, OB-fold

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0006956  complement activation
GO:0006957  complement activation, alternative pathway
GO:0006958  complement activation, classical pathway
GO:0006631  fatty acid metabolic process
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0006629  lipid metabolic process
GO:0001970  positive regulation of activation of membrane attack complex
GO:0045766  positive regulation of angiogenesis
GO:0048639  positive regulation of developmental growth
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0045745  positive regulation of G-protein coupled receptor protein signaling pathway
GO:0010828  positive regulation of glucose transport
GO:0010884  positive regulation of lipid storage
GO:0050766  positive regulation of phagocytosis
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0001798  positive regulation of type IIa hypersensitivity
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0010866  regulation of triglyceride biosynthetic process

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0070062  extracellular vesicular exosome

Molecular Function

GO:0031715  C5L2 anaphylatoxin chemotactic receptor binding
GO:0048037  cofactor binding
GO:0004866  endopeptidase inhibitor activity
GO:0008289  lipid binding
GO:0005515  protein binding