caspase 8

詳細情報を見る

同義遺伝子名

caspase 8, Casp8, MACH, CASP-8, Caspase-8 precursor, FLICE, Caspase-8, Mch5

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:133.80 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:518.50 末梢血:100.60 脾臓:539.80 胸腺:- 骨髄:282.10 脂肪:- 骨:75.10 皮膚:39.60
GeneChip 大脳:5.40 小脳:5.42 脳幹:- 脳梁:- 松果体:- 末梢神経:5.09 脊柱:5.61 網膜:5.54 目:6.20 動脈:- 静脈:8.65 リンパ節:10.92 末梢血:- 脾臓:10.07 胸腺:- 骨髄:9.82 脂肪:8.99 骨:9.29 皮膚:8.30
CAGE 大脳:1.49 小脳:- 脳幹:1.62 脳梁:- 松果体:- 末梢神経:- 脊柱:1.94 網膜:- 目:- 動脈:3.84 静脈:- リンパ節:5.71 末梢血:- 脾臓:4.01 胸腺:4.11 骨髄:- 脂肪:- 骨:4.21 皮膚:3.92
RNA-seq 大脳:1.15 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:37 結腸:17.60     肝臓:45.30        肺:10    膀胱:- 腎臓:80.60 下垂体:- 甲状腺:112.50 副腎:- 膵臓:9.40 乳腺:16.30 唾液腺:-
GeneChip 子宮:9.54 胎盤:7.72 前立腺:8.80 卵巣:8.71 精巣:5.62 心臓:6.83 骨格筋:7.56 食道:- 胃:9.64 腸:10.70 結腸:- 肝臓:9.37 肺:8.91 膀胱:8.30 腎臓:8.57 下垂体:6.83 甲状腺:- 副腎:8.66 膵臓:7.54 乳腺:9 唾液腺:8.71
CAGE 子宮:4.20 胎盤:2.94 前立腺:3.50 卵巣:3.50 精巣:1.97 心臓:- 骨格筋:- 食道:- 胃:4.14 腸:4.80 結腸:4.78     肝臓:3.92    肺:4.06 膀胱:3.58 腎臓:- 下垂体:3.06 甲状腺:- 副腎:3.54 膵臓:2.45 乳腺:3.84 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.21 食道:- 胃:- 腸:- 結腸:-     肝臓:3.93        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001080126
Gene ID 12370
Unigene ID Mm.336851
Probe set ID 1424552_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026029

オーソログ対応遺伝子

ヒト[11]  NM_001080124, NM_001080125, NM_001228, NM_033355, NM_033356, NM_033358
ラット[1]  NM_022277, NM_001080125, NM_001228, NM_033355, NM_033356, NM_033358

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9654089
9729047
9763668
9837723
9988219
10087912
10101687
10349636
10403638
10433968
10442092
10578172
10588860
10618441
10671365
10739648
10739653
10955330
11016460
11042159
11076861
11217851
11241200
11247636
11369777
11526440
11684016
11707574
11716543
11739563
12011074
12065591
12389034
12393559
12404118
12441076
12466851
12477932
12480175
12581736
12614028
12616497
12654726
12724324
12754217
14551216
14560027
14657025
14688275
14748698
14993216
15017386
15131264
15163747
15214581
15262979
15322156
15337828
15355863
15383280
15389560
15456877
15489334
15746428
15778357
15782199
15879131
15941915
15972663
15987939
16096375
16141072
16141073
16148088
16157684
16183742
16245150
16263940
16285959
16314469
16330535
16362053
16397188
16397500
16436380
16469705
16585540
16602821
16888816
16964442
17108969
17159908
17170703
17213198
17218430
17276340
17297564
17385212
17462996
17488888
17563067
17601517
17624595
17699753
17911615
17947688
18191273
18288386
18299403
18309324
18455983
18467326
18555200
18566604
18614015
18636075
18684943
18725521
18802959
18927586
18946037
19029301
19119023
19122169
19194987
19204729
19325570
19420112
19605759
19621384
19644511
19671668
19682497
19720838
19801895
19924290
19933859
20077182
20103947
20336607
20353946
20372860
20478530
20523353
20671745
20961848
21135236
21153328
21221781
21267068
21339290
21368762
21368763
21382479
21389984
21402742
21419663
21444671
21517838
21576355
21628531
21677750
21746883
21791606
21880664
21921917
21938487
21954216
21957448
21984154
22006951
22037414
22089168
22095280
22193709
22266786
22343728
22362782
22555457
22675671
22815944
22819539
23071110
23144495
23159925
23209324
23239879
23260196
23264463
23339067
23487422
23509366
23519075
23536557
23645208
23728913
23828572
23850678
23898178
23922164
23972991
23982205
24019532
24072877
24078693
24095739
24113711
24123685
24244021
24275659
24391214
24453255
24489101
24632563
24799678
24799700

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0007507  heart development
GO:0008625  induction of apoptosis via death domain receptors
GO:0030225  macrophage differentiation
GO:0008152  metabolic process
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0001841  neural tube formation
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045651  positive regulation of macrophage differentiation
GO:0045862  positive regulation of proteolysis
GO:0051291  protein heterooligomerization
GO:0006508  proteolysis
GO:0051603  proteolysis involved in cellular protein catabolic process
GO:0042981  regulation of apoptosis
GO:0070243  regulation of thymocyte apoptosis
GO:0045471  response to ethanol
GO:0034612  response to tumor necrosis factor

Cellular Component

GO:0031265  CD95 death-inducing signaling complex
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0031264  death-inducing signaling complex
GO:0045121  membrane raft
GO:0005739  mitochondrion
GO:0043005  neuron projection
GO:0030690  Noc1p-Noc2p complex
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0008234  cysteine-type peptidase activity
GO:0016787  hydrolase activity
GO:0042802  identical protein binding
GO:0008233  peptidase activity
GO:0002020  protease binding
GO:0005515  protein binding
GO:0005164  tumor necrosis factor receptor binding