runt related transcription factor 2

 詳細情報を見る

同義遺伝子名

SL3-3 enhancer factor 1 alpha A subunit, Runt-related transcription factor 2, Oncogene AML-3, PEBP2 alpha A, SL3/AKV core-binding factor alpha A subunit, Cbfa-1, Pebpa2a, LS3, Osf2, PEA2-alpha A, Osteoblast-specific transcription factor 2, Pebp2a, Acute myeloid leukemia 3 protein, SL3-3 enhancer factor 1, AML3, CBF-alpha 1, polyomavirus enhancer binding factor 2 (PEBP2), Aml3, PEBP2-alpha A, Runx2, PEBP2aA, Cbf, Core-binding factor, alpha 1 subunit, OSF-2, Cbfa1, Pebp2a1, runt related transcription factor 2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:4.95 小脳:4.16 脳幹:- 脳梁:- 松果体:- 末梢神経:5.13 脊柱:4.21 網膜:4.06 目:4.70 動脈:- 静脈:6.36 リンパ節:7.54 末梢血:- 脾臓:6.85 胸腺:- 骨髄:8.55 脂肪:6.13 骨:9.43 皮膚:5.36
CAGE 大脳:1.32 小脳:- 脳幹:0.83 脳梁:- 松果体:- 末梢神経:- 脊柱:0.91 網膜:- 目:- 動脈:0.83 静脈:- リンパ節:3.74 末梢血:- 脾臓:2.20 胸腺:1.69 骨髄:- 脂肪:- 骨:3.87 皮膚:2.66
RNA-seq 大脳:1.47 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:6.66 胎盤:5.07 前立腺:6.35 卵巣:10.13 精巣:4.30 心臓:4.45 骨格筋:4.61 食道:- 胃:5.05 腸:5.72 結腸:- 肝臓:3.89 肺:5.60 膀胱:5.66 腎臓:4.67 下垂体:4.30 甲状腺:- 副腎:8.97 膵臓:4.43 乳腺:5.57 唾液腺:9.84
CAGE 子宮:1.78 胎盤:1.97 前立腺:0.63 卵巣:4.06 精巣:2.64 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:1.60 結腸:2.39     肝臓:0.47    肺:2.55 膀胱:1.54 腎臓:- 下垂体:0.52 甲状腺:- 副腎:2.52 膵臓:0 乳腺:1.08 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.26 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_001145920
Gene ID 12393
Unigene ID Mm.391017
Probe set ID 1424704_at  [Mouse430_2]
Ensembl ID ENSMUSG00000039153

オーソログ対応遺伝子

ヒト [0]  
ラット [0]  

染色体

17B3  [44,632,936  -  44,951,746]
17B3  [44,744,480  -  44,951,746]

遺伝子ファミリー (Interpro ID)

IPR013524  Acute myeloid leukemia 1 (AML 1)/Runt
IPR000040  Acute myeloid leukemia 1 protein (AML 1)/Runt
IPR008967  p53-like transcription factor, DNA-binding
IPR012346  p53/RUNT-type transcription factor, DNA-binding domain
IPR016554  Transcription factor, Runt-related, RUNX

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0030509  BMP signaling pathway
GO:0048469  cell maturation
GO:0002063  chondrocyte development
GO:0002062  chondrocyte differentiation
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0001958  endochondral ossification
GO:0045879  negative regulation of smoothened signaling pathway
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0042475  odontogenesis of dentine-containing tooth
GO:0002076  osteoblast development
GO:0001649  osteoblast differentiation
GO:0002051  osteoblast fate commitment
GO:0008284  positive regulation of cell proliferation
GO:0032332  positive regulation of chondrocyte differentiation
GO:0045778  positive regulation of ossification
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0040036  regulation of fibroblast growth factor receptor signaling pathway
GO:0042487  regulation of odontogenesis of dentine-containing tooth
GO:0030278  regulation of ossification
GO:0045667  regulation of osteoblast differentiation
GO:0006355  regulation of transcription, DNA-dependent
GO:0001501  skeletal system development
GO:0048705  skeletal system morphogenesis
GO:0048863  stem cell differentiation
GO:0030217  T cell differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0005524  ATP binding
GO:0043425  bHLH transcription factor binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding