runt related transcription factor 1

詳細情報を見る

同義遺伝子名

Runx1, Pebpa2b, PEA2-alpha B, AI462102, runt domain, alpha subunit 2, Acute myeloid leukemia 1 protein, PEBP2-alpha B, SL3/AKV core-binding factor alpha B subunit, Aml1, Pebp2a2, runt related transcription factor 1, Core-binding factor, alpha 2 subunit, Runt-related transcription factor 1, SL3-3 enhancer factor 1 alpha B subunit, Pebp2ab, Cbfa2, CBF-alpha 2, AML1, Oncogene AML-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:10.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:22.80 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:19.80 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.35 小脳:4.79 脳幹:- 脳梁:- 松果体:- 末梢神経:9.18 脊柱:4.70 網膜:4.67 目:6.04 動脈:- 静脈:7.89 リンパ節:7.21 末梢血:- 脾臓:7.78 胸腺:- 骨髄:7.94 脂肪:6.04 骨:8.11 皮膚:7.18
CAGE 大脳:0.49 小脳:- 脳幹:0.93 脳梁:- 松果体:- 末梢神経:- 脊柱:1.17 網膜:- 目:- 動脈:2.37 静脈:- リンパ節:4.93 末梢血:- 脾臓:4.08 胸腺:4.90 骨髄:- 脂肪:- 骨:4.29 皮膚:3.98
RNA-seq 大脳:0.64 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:65.50 腸:- 結腸:-     肝臓:9.10        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:5.75 胎盤:7.33 前立腺:6.82 卵巣:7.69 精巣:4.44 心臓:5.34 骨格筋:5.50 食道:- 胃:6.21 腸:6.12 結腸:- 肝臓:4.77 肺:8.23 膀胱:7.87 腎臓:4.92 下垂体:4.99 甲状腺:- 副腎:5.32 膵臓:4.86 乳腺:7.17 唾液腺:6.84
CAGE 子宮:2.75 胎盤:4.23 前立腺:2.11 卵巣:3.88 精巣:0 心臓:- 骨格筋:- 食道:- 胃:3.36 腸:1.65 結腸:2.22     肝臓:1.12    肺:4.04 膀胱:3.72 腎臓:- 下垂体:1.81 甲状腺:- 副腎:1.89 膵臓:1.84 乳腺:3.35 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.04 食道:- 胃:- 腸:- 結腸:-     肝臓:0.51        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001111021
Gene ID 12394
Unigene ID Mm.408150
Probe set ID 1422864_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022952

オーソログ対応遺伝子

ヒト[40]  NM_001001890, NM_001122607, NM_001754
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1720541
2249771
7607689
7609063
7647375
7774816
7835892
7862157
8035830
8164679
8384306
8395054
8437866
8537354
8565077
8575770
8622955
8929538
9054947
9159135
9199349
9233771
9234595
9558367
9590173
9794229
9811459
10075931
10207087
10207104
10219254
10226014
10340392
10349636
10610183
10720428
10903914
10943840
10979955
11042159
11070161
11076861
11120804
11168593
11179217
11180952
11203699
11217851
11243869
11257229
11265752
11375505
11483356
11673502
11731260
12049718
12086889
12091336
12093746
12217689
12218099
12376107
12417632
12464175
12466851
12466854
12466855
12477932
12495904
12499254
12509458
12551949
12617847
12665593
12732184
12794114
12796513
12807882
12807883
12811823
12835475
12917624
12946863
14504086
14507780
14516670
14525762
14630789
14681479
14747476
14752096
14966519
15030765
15034051
15070703
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15136142
15155459
15156179
15240886
15253936
15271791
15297309
15355562
15361869
15389629
15514019
15592512
15618518
15713794
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15737933
15749889
15778374
15780989
15784726
15828028
15856017
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15882575
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16007221
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19570513
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19703295
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19800266
19801444
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19917773
20007544
20008790
20035012
20059953
20096094
20102410
20139099
20152828
20181744
20187849
20194037
20195544
20206228
20308320
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20430957
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20534675
20554972
20628604
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20660741
20673362
20699440
20711984
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20876651
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21170035
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23979164
24030384
24037986
24058535
24095735
24098673
24310293
24316076
24462289
24582971
24677539

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048266  behavioral response to pain
GO:0007417  central nervous system development
GO:0060216  definitive hemopoiesis
GO:0035162  embryonic hemopoiesis
GO:0031069  hair follicle morphogenesis
GO:0030097  hemopoiesis
GO:0001701  in utero embryonic development
GO:0001889  liver development
GO:0030099  myeloid cell differentiation
GO:0002318  myeloid progenitor cell differentiation
GO:0030853  negative regulation of granulocyte differentiation
GO:0048666  neuron development
GO:0030182  neuron differentiation
GO:0045766  positive regulation of angiogenesis
GO:0030854  positive regulation of granulocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0071336  regulation of hair follicle cell proliferation
GO:0009966  regulation of signal transduction
GO:0006355  regulation of transcription, DNA-dependent
GO:0032526  response to retinoic acid
GO:0001501  skeletal system development
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005604  basement membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0005509  calcium ion binding
GO:0003677  DNA binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding