cyclin-dependent kinase 5

同義遺伝子名

Tau protein kinase II catalytic subunit, Crk6, Cell division protein kinase 5, cyclin-dependent kinase 5, CRK6, TPKII catalytic subunit, Cdk5, Serine/threonine-protein kinase PSSALRE, AW048668

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:166.70

小脳:18.40

脳幹:31.80

脳梁:-

松果体:515.60

末梢神経:95.50

脊柱:-

網膜:96.40

目:7.60

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:52.70

胸腺:69.20

骨髄:-

脂肪:212.70

骨:50.10

皮膚:7.90

GeneChip

大脳:9.78

小脳:9.32

脳幹:-

脳梁:-

松果体:-

末梢神経:10.13

脊柱:10

網膜:7.28

目:6.59

動脈:-

静脈:8.18

リンパ節:8.16

末梢血:-

脾臓:8.03

胸腺:-

骨髄:7.74

脂肪:8.91

骨:7.52

皮膚:7.65

CAGE

大脳:4.50

小脳:-

脳幹:4.77

脳梁:-

松果体:-

末梢神経:-

脊柱:4.57

網膜:-

目:-

動脈:3.55

静脈:-

リンパ節:3.42

末梢血:-

脾臓:2.99

胸腺:3.38

骨髄:-

脂肪:-

骨:3.14

皮膚:3.41

RNA-seq

大脳:17.48

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:55.20

前立腺:-

卵巣:-

精巣:-

心臓:74.40

骨格筋:-

食道:-

胃:-

腸:-

結腸:35.20

肝臓:-

肺:10

膀胱:-

腎臓:-

下垂体:51.70

甲状腺:-

副腎:-

膵臓:197

乳腺:35.90

唾液腺:-

GeneChip

子宮:8.50

胎盤:8.38

前立腺:8.33

卵巣:8.63

精巣:8.44

心臓:7.64

骨格筋:7.82

食道:-

胃:8.34

腸:8.17

結腸:-

肝臓:8.29

肺:7.88

膀胱:8.14

腎臓:8.51

下垂体:9.12

甲状腺:-

副腎:8.70

膵臓:8.12

乳腺:8.05

唾液腺:8.36

CAGE

子宮:3.48

胎盤:3.56

前立腺:3.64

卵巣:3.65

精巣:3.67

心臓:-

骨格筋:-

食道:-

胃:3.69

腸:3.41

結腸:3.63

肝臓:3.56

肺:3.43

膀胱:3.65

腎臓:-

下垂体:4.13

甲状腺:-

副腎:3.72

膵臓:3.53

乳腺:3.21

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.46

食道:-

胃:-

腸:-

結腸:-

肝臓:4.08

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007668
Gene ID	12568
Unigene ID	Mm.298798
Probe set ID	1450674_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028969

オーソログ対応遺伝子

ヒト[2]	NM_001164410, NM_004935
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0008306	associative learning
GO:0007409	axonogenesis
GO:0048148	behavioral response to cocaine
GO:0070509	calcium ion import
GO:0007049	cell cycle
GO:0008219	cell death
GO:0051301	cell division
GO:0016477	cell migration
GO:0007160	cell-matrix adhesion
GO:0021954	central nervous system neuron development
GO:0021695	cerebellar cortex development
GO:0021697	cerebellar cortex formation
GO:0021549	cerebellum development
GO:0021987	cerebral cortex development
GO:0022038	corpus callosum development
GO:0030866	cortical actin cytoskeleton organization
GO:0048813	dendrite morphogenesis
GO:0009790	embryonic development
GO:0006887	exocytosis
GO:0030900	forebrain development
GO:0021766	hippocampus development
GO:0006886	intracellular protein transport
GO:0021819	layer formation in the cerebral cortex
GO:0008045	motor axon guidance
GO:0030517	negative regulation of axon extension
GO:0045786	negative regulation of cell cycle
GO:0046826	negative regulation of protein export from nucleus
GO:0031397	negative regulation of protein ubiquitination
GO:0031914	negative regulation of synaptic plasticity
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0007399	nervous system development
GO:0051402	neuron apoptosis
GO:0030182	neuron differentiation
GO:0001764	neuron migration
GO:0031175	neuron projection development
GO:0048812	neuron projection morphogenesis
GO:0006913	nucleocytoplasmic transport
GO:0048709	oligodendrocyte differentiation
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0016310	phosphorylation
GO:0045956	positive regulation of calcium ion-dependent exocytosis
GO:0043525	positive regulation of neuron apoptosis
GO:0032092	positive regulation of protein binding
GO:0045860	positive regulation of protein kinase activity
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0032801	receptor catabolic process
GO:0043113	receptor clustering
GO:0045055	regulated secretory pathway
GO:0030334	regulation of cell migration
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0060078	regulation of postsynaptic membrane potential
GO:0048167	regulation of synaptic plasticity
GO:0042220	response to cocaine
GO:0009611	response to wounding
GO:0014044	Schwann cell development
GO:0019233	sensory perception of pain
GO:0033136	serine phosphorylation of STAT3 protein
GO:0007519	skeletal muscle tissue development
GO:0007416	synapse assembly
GO:0001963	synaptic transmission, dopaminergic
GO:0035249	synaptic transmission, glutamatergic
GO:0048488	synaptic vesicle endocytosis
GO:0021537	telencephalon development
GO:0008542	visual learning

Cellular Component

GO:0030424	axon
GO:0030054	cell junction
GO:0042995	cell projection
GO:0043025	cell soma
GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0030425	dendrite
GO:0030175	filopodium
GO:0030426	growth cone
GO:0030027	lamellipodium
GO:0016020	membrane
GO:0031594	neuromuscular junction
GO:0044428	nuclear part
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0045202	synapse

Molecular Function

GO:0030549	acetylcholine receptor activator activity
GO:0005524	ATP binding
GO:0004693	cyclin-dependent protein kinase activity
GO:0046875	ephrin receptor binding
GO:0005176	ErbB-2 class receptor binding
GO:0043125	ErbB-3 class receptor binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0002039	p53 binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0050321	tau-protein kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

cyclin-dependent kinase 5

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function